PANTHER Gene Information

Gene Symbol(s):

Ak1

Organism:

Mus musculus

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Gene Name:

Adenylate kinase isoenzyme 1

Gene ID:

MGI:87977

Protein ID:

Q9R0Y5

Persistent Id:

PTN000599808

Alternate Ids:

MGI:87977(MGI)	568912818(GI)
Q9R0Y4(AltAccession)	KAD1_MOUSE(UniProtKB-ID)
CAM16613(EMBL-CDS)	ENSMUSG00000026817(Ensembl)
AJ010108(EMBL)	2.7.4.6 {ECO:0000255\|HAMAP-Rule:MF_03171}(EC)
11636(GeneID)	XM_006497624(refSeq)
Ak1(Symbol)	Myokinase {ECO:0000255\|HAMAP-Rule:MF_03171}(Synonym)
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PANTHER Classification

PANTHER Family:	NUCLEOTIDE KINASE (PTHR23359)
PANTHER Subfamily:	ADENYLATE KINASE ISOENZYME 1 (PTHR23359:SF59)
PANTHER GO-slim Molecular Function:	kinase activity phosphotransferase activity, phosphate group as acceptor
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	cytosol
PANTHER protein class:	nucleotide kinase

Pathway Categories:

De novo purine biosynthesis

Adenylate kinase

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	adenylate kinase activity, ATP binding, nucleoside diphosphate kinase activity, deoxyadenylate kinase activity, phosphotransferase activity, phosphate group as acceptor
GO BP Complete:	positive regulation of D-glucose transmembrane transport, ADP biosynthetic process, AMP metabolic process, nucleoside triphosphate biosynthetic process, ATP metabolic process, inosine biosynthetic process, nucleoside monophosphate phosphorylation
GO CC Complete:	outer dense fiber, perinuclear region of cytoplasm, cytoplasm, cytosol, sperm flagellum, sarcomere

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Metabolism of nucleotides, Metabolism, Interconversion of nucleotide di- and triphosphates

Orthologs

ID	Organism	Type
HUMAN\|HGNC=361\|UniProtKB=P00568	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000021402.7\|UniProtKB=K7AP41	Pan troglodytes	LDO
MACMU\|Ensembl=ENSMMUG00000060702.1\|UniProtKB=F6TT84	Macaca mulatta	LDO
RAT\|RGD=2076\|UniProtKB=P39069	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000006305\|UniProtKB=P00570	Bos taurus	LDO
HORSE\|Ensembl=ENSECAG00000055943.1\|UniProtKB=F6TL52	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000023313.4\|UniProtKB=M3WX07	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845005295.1\|UniProtKB=A0A8I3MQJ7	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000005639.4\|UniProtKB=A0A5F8HBA4	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000038287.1\|UniProtKB=A0A6I8PBR1	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010028082\|UniProtKB=P05081	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000017753.4\|UniProtKB=H9GPM1	Anolis carolinensis	LDO
XENLA\|Gene=ak1.L\|UniProtKB=Q66J33	Xenopus laevis	O
XENLA\|Gene=ak1.S\|UniProtKB=A0A1L8F1P8	Xenopus laevis	LDO
XENTR\|Gene=ak1\|UniProtKB=A0A8J1IL77	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000006708.2\|UniProtKB=A0A3B3IL06	Oryzias latipes	LDO
DANRE\|Gene=ak1\|UniProtKB=A0A8M2BGJ7	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000003793.1\|UniProtKB=W5M820	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000006951.3\|UniProtKB=F6VN10	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118416321\|UniProtKB=A0A9J7L6M4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118415962\|UniProtKB=A0A9J7L6B8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118420803\|UniProtKB=A0A9J7LIQ4	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC115929143\|UniProtKB=A0A7M7PLP8	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC588348\|UniProtKB=A2T1M5	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00009531\|UniProtKB=Q20140	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00037023\|UniProtKB=A8XQX9	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00089619\|UniProtKB=A0A2A6BF48	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0022709\|UniProtKB=Q8IQG9	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP009317\|UniProtKB=A0A1S4H0S9	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC014052\|UniProtKB=D6WJX8	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC008108\|UniProtKB=D1ZZU3	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC014051\|UniProtKB=D6WJX7	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_108672\|UniProtKB=E9H0V6	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_307177\|UniProtKB=E9H0V7	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW000200\|UniProtKB=B7P6S7	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG62268\|UniProtKB=T1FWY1	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG172327\|UniProtKB=T1F574	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG186024\|UniProtKB=T1FNK1	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g16747\|UniProtKB=A7SBK9	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG21322\|UniProtKB=B3RP24	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_19069\|UniProtKB=A9UP78	Monosiga brevicollis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_28095\|UniProtKB=F4PCT8	Batrachochytrium dendrobatidis	LDO
TRIV3\|Gene_ORFName=TVAG_273750\|UniProtKB=A2EI52	Trichomonas vaginalis	LDO
TRIV3\|Gene_ORFName=TVAG_179660\|UniProtKB=A2F448	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_130730\|UniProtKB=A2FTA8	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_493000\|UniProtKB=A2FUU3	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_070830\|UniProtKB=A2D7Y6	Trichomonas vaginalis	O
PLAF7\|EnsemblGenome=PF3D7_0305800\|UniProtKB=O97242	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00001523001\|UniProtKB=A0CX03	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00002534001\|UniProtKB=A0DQ17	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00006874001\|UniProtKB=A0C9V0	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00002419001\|UniProtKB=A0DGX3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00021699001\|UniProtKB=A0DZR4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00023382001\|UniProtKB=A0E4J0	Paramecium tetraurelia	LDO
CHLRE\|EnsemblGenome=CHLRE_08g377350v5\|UniProtKB=A0A2K3DHS7	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_01g029750v5\|UniProtKB=A0A2K3E6L7	Chlamydomonas reinhardtii	LDO
SELML\|EnsemblGenome=SELMODRAFT_5337\|UniProtKB=D8S4F6	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_85389\|UniProtKB=D8R6J3	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c25_7600\|UniProtKB=A9S600	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c4_19940\|UniProtKB=A0A2K1KP61	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0153s0020\|UniProtKB=A0A2R6W4X6	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_006740070\|UniProtKB=A0A1Y1IJ11	Klebsormidium nitens	LDO
KORCO\|EnsemblGenome=Kcr_1559\|UniProtKB=B1L775	Korarchaeum cryptofilum	O
HALSA\|EnsemblGenome=VNG_1724G\|UniProtKB=Q9HPA7	Halobacterium salinarum	O
THEKO\|EnsemblGenome=TK0812\|UniProtKB=Q5JH68	Thermococcus kodakaraensis	O
CHLAA\|EnsemblGenome=Caur_2957\|UniProtKB=A9WG02	Chloroflexus aurantiacus	O
CHLAA\|EnsemblGenome=Caur_2390\|UniProtKB=A9WH87	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO4723\|UniProtKB=P43414	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=Rv0733\|UniProtKB=P9WKF5	Mycobacterium tuberculosis	O
CLOBH\|Gene_OrderedLocusName=CBO3460\|UniProtKB=A5I7I5	Clostridium botulinum	O
STRR6\|EnsemblGenome=spr0210\|UniProtKB=Q8DRD4	Streptococcus pneumoniae	O
STAA8\|EnsemblGenome=SAOUHSC_02490\|UniProtKB=Q2FW27	Staphylococcus aureus	O
LISMO\|EnsemblGenome=CAD00689\|UniProtKB=Q8Y449	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_01370\|UniProtKB=P16304	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_0152\|UniProtKB=Q81J22	Bacillus cereus	O
THEMA\|EnsemblGenome=TM_1479\|UniProtKB=Q9X1I8	Thermotoga maritima	O
GLOVI\|EnsemblGenome=BAC89333\|UniProtKB=Q7NKT5	Gloeobacter violaceus	O
SYNY3\|EnsemblGenome=BAA16643\|UniProtKB=P72641	Synechocystis	O
SYNY3\|EnsemblGenome=BAA17330\|UniProtKB=P73302	Synechocystis	O
LEPIN\|EnsemblGenome=LA_0760\|UniProtKB=Q9XD15	Leptospira interrogans	O
BACTN\|EnsemblGenome=BT_4387\|UniProtKB=Q89ZJ0	Bacteroides thetaiotaomicron	O
CHLTR\|EnsemblGenome=CT_128\|UniProtKB=O84130	Chlamydia trachomatis	O
RHOBA\|EnsemblGenome=RB7867\|UniProtKB=Q7UN00	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_078\|UniProtKB=O66490	Aquifex aeolicus	O
THEYD\|EnsemblGenome=THEYE_A1836\|UniProtKB=B5YHP1	Thermodesulfovibrio yellowstonii	O
DICTD\|EnsemblGenome=Dtur_1001\|UniProtKB=B8E1F3	Dictyoglomus turgidum	O
FUSNN\|EnsemblGenome=FN1298\|UniProtKB=Q8RE31	Fusobacterium nucleatum	O
HELPY\|EnsemblGenome=HP_0618\|UniProtKB=P56104	Helicobacter pylori	O
NEIMB\|EnsemblGenome=NMB0823\|UniProtKB=P0A0U7	Neisseria meningitidis serogroup b	O
GEOSL\|EnsemblGenome=GSU2836\|UniProtKB=Q749A8	Geobacter sulfurreducens	O
BRADU\|Gene=adk\|UniProtKB=Q89JA5	Bradyrhizobium diazoefficiens	O
COXBU\|EnsemblGenome=CBU_0454\|UniProtKB=Q83E75	Coxiella burnetii	O
HAEIN\|EnsemblGenome=HI_0349\|UniProtKB=P24323	Haemophilus influenzae	O
SHEON\|Gene_OrderedLocusName=SO_2018\|UniProtKB=Q8EFF5	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_0986\|UniProtKB=Q9KTB7	Vibrio cholerae	O
PSEAE\|EnsemblGenome=PA3686\|UniProtKB=Q9HXV4	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM0488\|UniProtKB=P0A1V4	Salmonella typhimurium	O
YERPE\|EnsemblGenome=YP_0812\|UniProtKB=O69172	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAE76253\|UniProtKB=P69441	Escherichia coli	O