PANTHER Gene Information   
Gene Symbol(s): MC1R
Organism: Homo sapiens
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Gene Name: Melanocyte-stimulating hormone receptor
Gene ID: HGNC:6929
Protein ID: Q01726
Enhancers: View enhancers for HUMAN|HGNC=6929|UniProtKB=Q01726
Genetic Variant Annotation: Annoq
Persistent Id: PTN002503561
Alternate Ids:
613098(MIM) CHEMBL3795(ChEMBL)
NP_002377(refSeq) Q8WWX6(AltAccession)
MSHR_HUMAN(UniProtKB-ID) 18138240(GI)
HGNC:6929(HGNC) AAD41351(EMBL-CDS)
ENSG00000258839(Ensembl) ENSP00000451605(Ensembl_PRO)
4157(GeneID) X65634(EMBL)
ENST00000555147(Ensembl_TRS) MSHR(Synonym)
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PANTHER Classification
PANTHER Family: G-PROTEIN COUPLED RECEPTOR (PTHR22750)
PANTHER Subfamily: MELANOCYTE-STIMULATING HORMONE RECEPTOR (PTHR22750:SF2)  
PANTHER GO-slim Molecular Function: G protein-coupled peptide receptor activity
PANTHER GO-slim Biological Process: regulation of metabolic process
adenylate cyclase-activating G protein-coupled receptor signaling pathway
PANTHER GO-slim Cellular Component: plasma membrane
cytoplasm
PANTHER protein class: G-protein coupled receptor
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: G protein-coupled receptor activity, melanocortin receptor activity, G protein-coupled peptide receptor activity, protein binding, ubiquitin protein ligase binding, hormone binding, melanocyte-stimulating hormone receptor activity
GO BP Complete: melanin biosynthetic process, UV-damage excision repair, positive regulation of cAMP/PKA signal transduction, G protein-coupled receptor signaling pathway, signal transduction, G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, UV protection, adenylate cyclase-activating G protein-coupled receptor signaling pathway, phospholipase C-activating G protein-coupled receptor signaling pathway, positive regulation of transcription by RNA polymerase II, regulation of feeding behavior, pigmentation, regulation of metabolic process, sensory perception of pain, positive regulation of feeding behavior, negative regulation of tumor necrosis factor production, intracellular signal transduction
GO CC Complete: cytoplasm, membrane, plasma membrane
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Signal Transduction, GPCR downstream signalling, G alpha (s) signalling events, Peptide ligand-binding receptors, Signaling by GPCR, GPCR ligand binding, Class A/1 (Rhodopsin-like receptors)

Orthologs