PANTHER Gene Information

Gene Symbol(s):

Wdr1

Organism:

Rattus norvegicus

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Gene Name:

WD repeat-containing protein 1

Gene ID:

1305789

Protein ID:

Q5RKI0

Persistent Id:

PTN000458128

Alternate Ids:

360950(GeneID)	AAH85864(EMBL-CDS)
WDR1(Synonym)	BC085864(EMBL)
Wdr1(Symbol)	ENSRNOT00000024012(Ensembl_TRS)
ENSRNOG00000028498(Ensembl)	1305789(RGD)
ENSRNOP00000024012(Ensembl_PRO)	81910041(GI)
WDR1_RAT(UniProtKB-ID)	NM_001014135(refSeq)
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PANTHER Classification

PANTHER Family:	WD-REPEATCONTAINING PROTEIN WDR1 (PTHR19856)
PANTHER Subfamily:	WD REPEAT-CONTAINING PROTEIN 1 (PTHR19856:SF0)
PANTHER GO-slim Molecular Function:	actin filament binding
PANTHER GO-slim Biological Process:	actin filament depolymerization
PANTHER GO-slim Cellular Component:	cortical actin cytoskeleton
PANTHER protein class:	non-motor actin binding protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	actin filament binding
GO BP Complete:	regulation of cell shape, locomotion, actin filament depolymerization, sarcomere organization, regulation of oligodendrocyte differentiation, regulation of ventricular cardiac muscle cell membrane repolarization, establishment of planar polarity of follicular epithelium, cortical cytoskeleton organization, neutrophil migration, neutrophil mediated immunity, regulation of actin filament depolymerization, maintenance of epithelial cell apical/basal polarity, positive regulation of actin filament depolymerization, apical junction assembly, platelet formation, actin filament fragmentation, actin cytoskeleton organization
GO CC Complete:	cell-cell junction, actin cytoskeleton, cytosol, cell junction, synapse, glutamatergic synapse, cell projection, plasma membrane, cortical actin cytoskeleton, podosome

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Hemostasis, Platelet activation, signaling and aggregation, Platelet degranulation , Response to elevated platelet cytosolic Ca2+

Orthologs

ID	Organism	Type
HUMAN\|HGNC=12754\|UniProtKB=O75083	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000015916.6\|UniProtKB=A0A2J8NWJ5	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000015364.3\|UniProtKB=G3RYA3	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000000960.4\|UniProtKB=A0A5K1VT58	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1337100\|UniProtKB=O88342	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000013607.6\|UniProtKB=F1MTP5	Bos taurus	O
BOVIN\|Gene=WDR1\|UniProtKB=Q2KJH4	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000036501.3\|UniProtKB=K9IVR7	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000018435.4\|UniProtKB=F6Z8W0	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000011317.6\|UniProtKB=M3WEW2	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845002747.1\|UniProtKB=A0A8I3MN98	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000001392.4\|UniProtKB=F7F5P3	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000012065.3\|UniProtKB=F7FW87	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010009542.1\|UniProtKB=A0A8V0Y2I4	Gallus gallus	O
CHICK\|Gene=WDR1\|UniProtKB=O93277	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000010583.3\|UniProtKB=H9GGR3	Anolis carolinensis	LDO
XENLA\|Gene=wdr1-a\|UniProtKB=Q9W7F2	Xenopus laevis	O
XENLA\|Gene=wdr1-b\|UniProtKB=Q6PAX7	Xenopus laevis	LDO
ORYLA\|Ensembl=ENSORLG00000008386.2\|UniProtKB=H2LWP5	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-804\|UniProtKB=Q7ZVQ3	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000009921.1\|UniProtKB=W5MUS3	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118414610\|UniProtKB=A0A9J7L3E4	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC587013\|UniProtKB=A0A7M7SZ73	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00010685\|UniProtKB=O17939	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00041133\|UniProtKB=A8Y2N7	Caenorhabditis briggsae	LDO
CAEEL\|WormBase=WBGene00006810\|UniProtKB=Q11176	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00034778\|UniProtKB=A8XJI3	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00304898\|UniProtKB=A0A8R1V6D2	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00280701\|UniProtKB=A0A454Y7G1	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0260049\|UniProtKB=Q9VU68	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP002509\|UniProtKB=Q7PRC8	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC005722\|UniProtKB=D6WWM4	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_330309\|UniProtKB=E9HJ64	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG156976\|UniProtKB=T1EM43	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g247604\|UniProtKB=A7SV89	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g164461\|UniProtKB=A7RZB4	Nematostella vectensis	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_35227\|UniProtKB=A9V547	Monosiga brevicollis	LDO
YEAST\|SGD=S000004698\|UniProtKB=P46680	Saccharomyces cerevisiae	LDO
EREGS\|Gene_OrderedLocusName=ADL054W\|UniProtKB=Q75AI1	Eremothecium gossypii	O
EREGS\|EnsemblGenome=AGOS_ABL043W\|UniProtKB=Q75DR0	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000188252\|UniProtKB=A0A1D8PSI3	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_E01870g\|UniProtKB=Q6C7C8	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_10942\|UniProtKB=C8VBC3	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_2G06040\|UniProtKB=Q4WHB0	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU03944\|UniProtKB=Q7RZB7	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_05236\|UniProtKB=A7EIU3	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_03264\|UniProtKB=Q0UYA0	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC9G1.05\|UniProtKB=O14301	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_03380\|UniProtKB=B6K431	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNC06370\|UniProtKB=Q5KJJ1	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_05949\|UniProtKB=A0A0D1DP36	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_18895\|UniProtKB=E3L8F6	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_14760\|UniProtKB=E3KW80	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_37053\|UniProtKB=F4P4V9	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_118160\|UniProtKB=C4LZ00	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=EHI_142190\|UniProtKB=B1N2S4	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0278733\|UniProtKB=P54686	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_51240\|UniProtKB=F1A2T1	Dictyostelium purpureum	LDO
TRYB2\|Gene_ORFName=Tb927.3.4660\|UniProtKB=Q582R9	Trypanosoma brucei	LDO
TRIV3\|Gene_ORFName=TVAG_018920\|UniProtKB=A2G492	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_333620\|UniProtKB=A2F8R8	Trichomonas vaginalis	LDO
PARTE\|EnsemblGenome=GSPATT00003940001\|UniProtKB=A0ECQ4	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_23728\|UniProtKB=B8C6R4	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GIL8_PHYRM\|UniProtKB=H3GIL8	Phytophthora ramorum	LDO
AMBTC\|EnsemblGenome=AMTR_s00005p00267370\|UniProtKB=W1PG68	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_226G00120\|UniProtKB=A0A0K9PKY0	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma03_g21900\|UniProtKB=A0A804IEV6	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma10_g19980\|UniProtKB=A0A804KY83	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_000728mg\|UniProtKB=K3XFQ9	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3003G089100\|UniProtKB=A0A1B6Q258	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb125700\|UniProtKB=B6UDC2	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb369430\|UniProtKB=A0A804R0X5	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb334960\|UniProtKB=C0P7E7	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os01g0125800\|UniProtKB=Q9AWU6	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_2g01827v3\|UniProtKB=A0A0Q3IQF5	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0222780\|UniProtKB=A0A8I6WMT9	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS3A02G047800\|UniProtKB=A0A3B6EAV0	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3D02G031900\|UniProtKB=A0A3B6GK82	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3B02G034400\|UniProtKB=A0A077RU32	Triticum aestivum	LDO
NELNU\|Gene=LOC104587785\|UniProtKB=A0A1U7Z856	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110788425\|UniProtKB=A0A9R0JVL7	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr10g0461081\|UniProtKB=A0A251TP50	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C500261600\|UniProtKB=A0A9R1XBE9	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a003089mg\|UniProtKB=A0A022RJP1	Erythranthe guttata	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400005655\|UniProtKB=M1A466	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc03g119080.3\|UniProtKB=A0A3Q7FW21	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107797995\|UniProtKB=A0A1S4AI79	Nicotiana tabacum	O
TOBAC\|Gene=LOC107811990\|UniProtKB=A0A1S4BUC4	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi17g00233\|UniProtKB=D7SJ83	Vitis vinifera	LDO
BRANA\|Gene_ORFName=DARMORV10_C09P30050.1\|UniProtKB=A0A078GL10	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A09P23310.1\|UniProtKB=A0A078HTA4	Brassica napus	O
BRACM\|EnsemblGenome=Bra017456\|UniProtKB=M4DLS5	Brassica campestris	O
ARATH\|TAIR=locus=2038761\|UniProtKB=Q9ZU34	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107921291\|UniProtKB=A0A1U8KW55	Gossypium hirsutum	O
GOSHI\|Gene=LOC107916902\|UniProtKB=A0A1U8KH44	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_010832\|UniProtKB=A0A061E7G8	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g007229mg\|UniProtKB=A0A067FMS6	Citrus sinensis	O
MANES\|EnsemblGenome=MANES_15G126700\|UniProtKB=A0A2C9UFF3	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_1289050\|UniProtKB=B9SYJ9	Ricinus communis	O
EUCGR\|EnsemblGenome=EUGRSUZ_K02263\|UniProtKB=A0A059A4C5	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00093466001\|UniProtKB=A0A078II14	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra022278\|UniProtKB=M4E0I1	Brassica campestris	LDO
ARATH\|TAIR=locus=2092742\|UniProtKB=Q9LV35	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107904673\|UniProtKB=A0A1U8J8E6	Gossypium hirsutum	O
GOSHI\|Gene=LOC107923817\|UniProtKB=A0A1U8L7U3	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_012627\|UniProtKB=A0A061FVZ2	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g007283mg\|UniProtKB=A0A067F6B2	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_015G041200v3\|UniProtKB=B9IE99	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_012G049200v3\|UniProtKB=B9I2G7	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_06G008300\|UniProtKB=A0A2C9VLU3	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1072140\|UniProtKB=B9T4F8	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_10G263900\|UniProtKB=K7LLJ5	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_20G126400\|UniProtKB=I1NFV4	Glycine max	O
MEDTR\|EnsemblGenome=MTR_1g107560\|UniProtKB=A0A072W1G5	Medicago truncatula	O
SOYBN\|EnsemblGenome=GLYMA_05G243900\|UniProtKB=I1K5E5	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_08G051900\|UniProtKB=I1KQI6	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_8g106820\|UniProtKB=Q1SN19	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr06_15220\|UniProtKB=A0A2I4E0S4	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_1G024940\|UniProtKB=A0A0A0LST9	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_5G230600\|UniProtKB=M5WDW0	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_182691\|UniProtKB=D8SU47	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_160579\|UniProtKB=D8T381	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c3_9960\|UniProtKB=F5CC80	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0025s0096\|UniProtKB=A0A2R6XBG0	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_001200140\|UniProtKB=A0A1Y1HVN4	Klebsormidium nitens	LDO