PANTHER Gene Information

Gene Symbol(s):

Pola2

Organism:

Mus musculus

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Gene Name:

DNA polymerase alpha subunit B

Gene ID:

MGI:99690

Protein ID:

P33611

Persistent Id:

PTN000551750

Alternate Ids:

BC064795(EMBL)	ENSMUSG00000024833(Ensembl)
DNA polymerase alpha 70 kDa subunit(Synonym)	AAH21424(EMBL-CDS)
ENSMUSP00000025752(Ensembl_PRO)	341940457(GI)
NP_032919(refSeq)	18969(GeneID)
DPOA2_MOUSE(UniProtKB-ID)	Q8VDR3(AltAccession)
ENSMUST00000025752(Ensembl_TRS)	Pola2(Symbol)
MGI:99690(MGI)
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PANTHER Classification

PANTHER Family:	DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT (PTHR23061)
PANTHER Subfamily:	DNA POLYMERASE ALPHA SUBUNIT B (PTHR23061:SF12)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	DNA replication initiation
PANTHER GO-slim Cellular Component:	nuclear DNA-directed RNA polymerase complex DNA polymerase complex replisome nuclear replication fork
PANTHER protein class:	DNA-directed DNA polymerase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	DNA binding, DNA-directed DNA polymerase activity, protein binding
GO BP Complete:	DNA replication initiation, DNA replication, protein import into nucleus, DNA replication, synthesis of primer
GO CC Complete:	nucleus, alpha DNA polymerase:primase complex, ciliary basal body, cytosol, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Orthologs

ID	Organism	Type
HUMAN\|HGNC=30073\|UniProtKB=Q14181	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000003870.3\|UniProtKB=H2Q426	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000003056.3\|UniProtKB=G3QKN0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000022031.4\|UniProtKB=F7HTD4	Macaca mulatta	LDO
RAT\|RGD=621817\|UniProtKB=O89043	Rattus norvegicus	LDO
BOVIN\|Gene=POLA2\|UniProtKB=Q58D13	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000011455.5\|UniProtKB=F1MXS4	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000012997.5\|UniProtKB=A0A287AFT6	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000024194.4\|UniProtKB=F6X9Q1	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000001440.5\|UniProtKB=M3VWM7	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845025031.1\|UniProtKB=A0A8I3PT48	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000009836.4\|UniProtKB=F6WAX6	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000014222.3\|UniProtKB=A0A6I8NN61	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010001378.1\|UniProtKB=A0A8V0XAW7	Gallus gallus	LDO
XENLA\|Gene=pola2.L\|UniProtKB=A0A1L8GJG1	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5916783\|UniProtKB=Q6DEY9	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000002903.2\|UniProtKB=H2LCJ1	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-778\|UniProtKB=B0S687	Danio rerio	LDO
BRAFL\|Gene=LOC118421393\|UniProtKB=A0A9J7LL66	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC574732\|UniProtKB=A0A7M7PT99	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00001002\|UniProtKB=Q21625	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00042057\|UniProtKB=A8WJB1	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00101672\|UniProtKB=A0A2A6CD40	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0005696\|UniProtKB=Q9VB62	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP004392\|UniProtKB=Q7PQA8	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC005585\|UniProtKB=D6WXD7	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_321802\|UniProtKB=E9GTY7	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG185050\|UniProtKB=T1FMB9	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g166478\|UniProtKB=A7S4W9	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG57222\|UniProtKB=B3RYU8	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_29731\|UniProtKB=A9VBY8	Monosiga brevicollis	LDO
YEAST\|SGD=S000000131\|UniProtKB=P38121	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_ADL299C\|UniProtKB=Q75B71	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000183205\|UniProtKB=A0A1D8PE62	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_E18832g\|UniProtKB=Q6C5E1	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_10855\|UniProtKB=C8V2N1	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_5G13020\|UniProtKB=Q4WVR2	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU03597\|UniProtKB=Q1K7S4	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_03587\|UniProtKB=A7EE47	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_10351\|UniProtKB=Q0UD13	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPCC553.09c\|UniProtKB=O74946	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_02172\|UniProtKB=B6K1R0	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNM01440\|UniProtKB=Q5K7S4	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_02557\|UniProtKB=A0A0D1DYS5	Ustilago maydis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_12741\|UniProtKB=F4P6Q4	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0282731\|UniProtKB=Q54S08	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_96307\|UniProtKB=F0Z768	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_32_1720\|UniProtKB=Q4Q5A8	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb11.01.6520\|UniProtKB=Q381U6	Trypanosoma brucei	LDO
TRIV3\|Gene_ORFName=TVAG_292080\|UniProtKB=A2DQY8	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_233230\|UniProtKB=A2ERZ2	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_1463300\|UniProtKB=Q8IKK3	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00006247001\|UniProtKB=A0C4N1	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_3787\|UniProtKB=B8BYS5	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GCG0_PHYRM\|UniProtKB=H3GCG0	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_01g017450v5\|UniProtKB=A0A2K3E5U8	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00066p00201540\|UniProtKB=U5DDP3	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_15G01010\|UniProtKB=A0A0K9PWZ1	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma03_g17950\|UniProtKB=A0A804IDC4	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_021465mg\|UniProtKB=K3Z4J7	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3010G103700\|UniProtKB=A0A1W0VSD3	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb409930\|UniProtKB=B4F916	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os12g0242900\|UniProtKB=Q0IP63	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_4g39480v3\|UniProtKB=I1ITD1	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.7HG0732610\|UniProtKB=F2EDP4	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS7A02G452800\|UniProtKB=A0A3B6RQ21	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7D02G442100\|UniProtKB=A0A3B6TQJ9	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7B02G352800\|UniProtKB=A0A3B6SRY9	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_004958\|UniProtKB=A0A1U7ZRK7	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110793923\|UniProtKB=A0A9R0IS32	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr06g0253781\|UniProtKB=A0A251UHD8	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C300113190\|UniProtKB=A0A9R1W5K8	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a003284mg\|UniProtKB=A0A022QDF6	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_27908\|UniProtKB=A0A2G2YFR2	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400017439\|UniProtKB=M1BGW7	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc05g014540.3\|UniProtKB=A0A3Q7GGU4	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107831849\|UniProtKB=A0A1S4DNX9	Nicotiana tabacum	O
TOBAC\|Gene=LOC107823792\|UniProtKB=A0A1S4CXX4	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi01g01559\|UniProtKB=D7TAP9	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_B03458\|UniProtKB=A0A059D816	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_C02P23270.1\|UniProtKB=A0A078H435	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A02P14390.1\|UniProtKB=A0A078FE60	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra033987\|UniProtKB=M4EYU5	Brassica campestris	LDO
ARATH\|TAIR=locus=2008580\|UniProtKB=F4HTP2	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107903900\|UniProtKB=A0A1U8JA97	Gossypium hirsutum	O
GOSHI\|Gene=LOC107898021\|UniProtKB=A0A1U8IRL7	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_010761\|UniProtKB=A0A061E859	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g0069761mg\|UniProtKB=A0A067GTK0	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_010G055900v3\|UniProtKB=U5G160	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_12G015200\|UniProtKB=A0A2C9UTS3	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1081910\|UniProtKB=B9RMM9	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_18G009300\|UniProtKB=I1MYI4	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_11G247900\|UniProtKB=I1LNB2	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_3g085750\|UniProtKB=G7JC29	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr16_13690\|UniProtKB=A0A2I4HMF5	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_1G039840\|UniProtKB=A0A0A0LQA4	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_1G233700\|UniProtKB=A0A251R294	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_138015\|UniProtKB=D8TEH5	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_110038\|UniProtKB=D8S6E2	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_23326\|UniProtKB=D8TEH3	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c10_15960\|UniProtKB=A0A2K1JZ79	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0035s0099\|UniProtKB=A0A2R6X5E4	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_004220150\|UniProtKB=A0A1Y1II98	Klebsormidium nitens	LDO