PANTHER Gene Information   
Gene Symbol(s): Smarca2
Organism: Mus musculus
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Gene Name: Probable global transcription activator SNF2L2
Gene ID: MGI:99603
Protein ID: Q6DIC0
Persistent Id: PTN000084836
Alternate Ids:
NP_035546(refSeq) ATP-dependent helicase SMARCA2(Synonym)
MGI:99603(MGI) SMCA2_MOUSE(UniProtKB-ID)
3.6.4.-(EC) 67155(GeneID)
AAH75641(EMBL-CDS) 49523317(GI)
Smarca2{ECO:0000312|MGI:MGI:99603}(Symbol) BC075641(EMBL)
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PANTHER Classification
PANTHER Family: SNF2/RAD54 HELICASE FAMILY (PTHR10799)
PANTHER Subfamily: GLOBAL TRANSCRIPTION ACTIVATOR SNF2L2-RELATED (PTHR10799:SF541)  
PANTHER GO-slim Molecular Function: ATP-dependent activity, acting on DNA
DNA binding
transcription factor binding
PANTHER GO-slim Biological Process: positive regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component: chromatin
nucleus
PANTHER protein class: DNA helicase
Pathway Categories: Wnt signaling pathway
   Switched/Sucrose Non Fermentation

GO MF Complete: DNA binding, ATP binding, protein binding, transcription coactivator activity, histone binding, transcription cis-regulatory region binding, helicase activity, chromatin binding, hydrolase activity, nucleosome array spacer activity
GO BP Complete: cell population proliferation, regulation of mitotic metaphase/anaphase transition, negative regulation of cell population proliferation, positive regulation of cell population proliferation, nervous system development, positive regulation of myoblast differentiation, chromatin organization, positive regulation of transcription by RNA polymerase II, regulation of nucleotide-excision repair, positive regulation of stem cell population maintenance, fibroblast proliferation, chromatin remodeling, negative regulation of DNA-templated transcription, negative regulation of cell growth, negative regulation of cell differentiation, positive regulation of DNA-templated transcription, negative regulation of fibroblast proliferation, hematopoietic stem cell homeostasis, positive regulation of cell differentiation, nucleosome assembly, regulation of transcription by RNA polymerase II, heterochromatin formation, positive regulation of T cell differentiation, regulation of G1/S transition of mitotic cell cycle, positive regulation of double-strand break repair, aortic smooth muscle cell differentiation, regulation of G0 to G1 transition
GO CC Complete: nucleus, SWI/SNF complex, intermediate filament cytoskeleton, npBAF complex, intracellular membrane-bounded organelle, bBAF complex, brahma complex, nBAF complex, SWI/SNF superfamily-type complex, chromatin, nucleoplasm, GBAF complex
Reactome Pathways: Chromatin organization, Generic Transcription Pathway, Transcriptional regulation by RUNX1, RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known, RMTs methylate histone arginines, Chromatin modifying enzymes, Gene expression (Transcription), RNA Polymerase II Transcription