PANTHER Gene Information   
Gene Symbol(s): Xrcc1
Organism: Mus musculus
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Gene Name: DNA repair protein XRCC1
Gene ID: MGI:99137
Protein ID: Q60596
Persistent Id: PTN000146451
Alternate Ids:
XRCC1(Synonym) 84028280(GI)
22594(GeneID) ENSMUSP00000146105(Ensembl_PRO)
BAE40272(EMBL-CDS) U02887(EMBL)
Q3THC5(AltAccession) NP_033558(refSeq)
MGI:99137(MGI) ENSMUSG00000051768(Ensembl)
ENSMUST00000205573(Ensembl_TRS) XRCC1_MOUSE(UniProtKB-ID)
Xrcc1(Symbol)
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PANTHER Classification
PANTHER Family: DNA-REPAIR PROTEIN XRCC1 (PTHR11370)
PANTHER Subfamily: DNA REPAIR PROTEIN XRCC1 (PTHR11370:SF5)  
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class: DNA metabolism protein
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: poly-ADP-D-ribose binding, 3' overhang single-stranded DNA endodeoxyribonuclease activity, oxidized DNA binding, ADP-D-ribose modification-dependent protein binding, enzyme binding
GO BP Complete: DNA repair, response to hydroperoxide, base-excision repair, negative regulation of protection from non-homologous end joining at telomere, hippocampus development, response to xenobiotic stimulus, double-strand break repair via nonhomologous end joining, positive regulation of single strand break repair, single strand break repair, response to hypoxia, voluntary musculoskeletal movement, replication-born double-strand break repair via sister chromatid exchange, negative regulation of protein ADP-ribosylation, telomeric DNA-containing double minutes formation
GO CC Complete: chromosome, telomeric region, nucleus, site of DNA damage, ERCC4-ERCC1 complex, nucleolus, chromatin, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: HDR through MMEJ (alt-NHEJ), DNA Repair, Base Excision Repair, Resolution of AP sites via the single-nucleotide replacement pathway, Homology Directed Repair, Transcription-Coupled Nucleotide Excision Repair (TC-NER), APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway, Gap-filling DNA repair synthesis and ligation in TC-NER, Nucleotide Excision Repair, DNA Double-Strand Break Repair, Resolution of Abasic Sites (AP sites)

Orthologs