PANTHER Gene Information

Gene Symbol(s):

Tbxa2r

Organism:

Mus musculus

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Gene Name:

Thromboxane A2 receptor

Gene ID:

MGI:98496

Protein ID:

P30987

Persistent Id:

PTN000221628

Alternate Ids:

ENSMUST00000105325(Ensembl_TRS)	MGI:98496(MGI)
ENSMUSP00000100962(Ensembl_PRO)	NM_001277265(refSeq)
CHEMBL1795181(ChEMBL)	21390(GeneID)
TA2R_MOUSE(UniProtKB-ID)	401152(GI)
BAA01622(EMBL-CDS)	Prostanoid TP receptor(Synonym)
Tbxa2r(Symbol)	D10849(EMBL)
ENSMUSG00000034881(Ensembl)
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PANTHER Classification

PANTHER Family:	G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER (PTHR11866)
PANTHER Subfamily:	THROMBOXANE A2 RECEPTOR (PTHR11866:SF5)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	regulation of anatomical structure size inflammatory response positive regulation of cytosolic calcium ion concentration positive regulation of multicellular organismal process regulation of blood pressure regulation of system process adenylate cyclase-activating G protein-coupled receptor signaling pathway
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	G-protein coupled receptor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	thromboxane receptor activity
GO BP Complete:	G protein-coupled receptor signaling pathway, positive regulation of blood coagulation, positive regulation of vasoconstriction, response to nutrient, adenylate cyclase-activating G protein-coupled receptor signaling pathway, response to xenobiotic stimulus, negative regulation of cell migration involved in sprouting angiogenesis, positive regulation of angiogenesis, positive regulation of blood pressure, positive regulation of cytosolic calcium ion concentration, positive regulation of smooth muscle contraction, response to ethanol, inflammatory response, cellular response to lipopolysaccharide, smooth muscle contraction, response to lipopolysaccharide, response to testosterone, regulation of vasoconstriction
GO CC Complete:	acrosomal vesicle, nuclear speck, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Eicosanoid ligand-binding receptors, GPCR ligand binding, G alpha (12/13) signalling events, Signal Transduction, Signal amplification, G alpha (q) signalling events, GPCR downstream signalling, Prostanoid ligand receptors, Thromboxane signalling through TP receptor, Platelet activation, signaling and aggregation, Hemostasis, Class A/1 (Rhodopsin-like receptors), Signaling by GPCR

Orthologs

ID	Organism	Type
HUMAN\|HGNC=11608\|UniProtKB=P21731	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000050832.1\|UniProtKB=K7BJ86	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000013761.3\|UniProtKB=G3S6J9	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000011403.4\|UniProtKB=F6VZF4	Macaca mulatta	LDO
RAT\|RGD=3825\|UniProtKB=P34978	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000014944\|UniProtKB=Q95125	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000033759.2\|UniProtKB=A0A287A102	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000038039.3\|UniProtKB=A0A9L0TVK7	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000012120.6\|UniProtKB=M3WGD1	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845008905.1\|UniProtKB=A0A8I3NCM2	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000006844.4\|UniProtKB=F6W8V3	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000037569.1\|UniProtKB=A0A6I8NK78	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010028120.1\|UniProtKB=A0A1D5P7R6	Gallus gallus	LDO
XENLA\|Gene=tbxa2r.S\|UniProtKB=A0A1L8HMZ3	Xenopus laevis	O
XENLA\|Gene=tbxa2r.L\|UniProtKB=Q6DCT4	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-996433\|UniProtKB=F7CRB6	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000006800.2\|UniProtKB=H2LR43	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-131016-6\|UniProtKB=T2HVK6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000000178.1\|UniProtKB=W5LVP1	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000006628.3\|UniProtKB=F6QP05	Ciona intestinalis	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_81312\|UniProtKB=C3YQU3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421591\|UniProtKB=A0A9J7LN18	Branchiostoma floridae	O
BRAFL\|Gene=LOC118428868\|UniProtKB=A0A9J7N8E2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421480\|UniProtKB=A0A9J7LKQ1	Branchiostoma floridae	O
BRAFL\|Gene=LOC118422573\|UniProtKB=A0A9J7LND4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118431987\|UniProtKB=A0A9J7MDP2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118422784\|UniProtKB=A0A9J7LQ10	Branchiostoma floridae	O
BRAFL\|Gene=LOC118410777\|UniProtKB=A0A9J7KQP6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118422170\|UniProtKB=A0A9J7N0F2	Branchiostoma floridae	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_126346\|UniProtKB=C3Y9X7	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC100893379\|UniProtKB=A0A7M7PG24	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105441389\|UniProtKB=A0A7M7HJN2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115918068\|UniProtKB=A0A7M7RJ18	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105442196\|UniProtKB=A0A7M7HM10	Strongylocentrotus purpuratus	O
DROME\|FlyBase=FBgn0036742\|UniProtKB=Q9VVJ1	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP001561\|UniProtKB=Q7PXU3	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC013650\|UniProtKB=D6WKK3	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_262904\|UniProtKB=E9HNW7	Daphnia pulex	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g205619\|UniProtKB=A7S259	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g91884\|UniProtKB=A7RSI2	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG53369\|UniProtKB=B3RP17	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG52708\|UniProtKB=B3RJX1	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG51529\|UniProtKB=B3RJN5	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG54207\|UniProtKB=B3RRE5	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG57256\|UniProtKB=B3RYY1	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG53885\|UniProtKB=B3RMB2	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG58786\|UniProtKB=B3S3N4	Trichoplax adhaerens	O