PANTHER Gene Information   
Gene Symbol(s): Sox4
Organism: Mus musculus
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Gene Name: Transcription factor SOX-4
Gene ID: MGI:98366
Protein ID: Q06831
Persistent Id: PTN000030598
Alternate Ids:
SOX4_MOUSE(UniProtKB-ID) NP_033264(refSeq)
MGI:98366(MGI) 341942057(GI)
ENSMUSP00000100013(Ensembl_PRO) 20677(GeneID)
SOX4(Synonym) Sox4{ECO:0000303|PubMed:23562159,ECO:0000312|MGI:MGI:98366}(Symbol)
X70298(EMBL) ENSMUST00000067230(Ensembl_TRS)
ENSMUSG00000076431(Ensembl) AAC52858(EMBL-CDS)
Q5SW95(AltAccession)
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PANTHER Classification
PANTHER Family: SOX TRANSCRIPTION FACTOR (PTHR10270)
PANTHER Subfamily: TRANSCRIPTION FACTOR SOX-4 (PTHR10270:SF27)  
PANTHER GO-slim Molecular Function: DNA-binding transcription activator activity, RNA polymerase II-specific
RNA polymerase II cis-regulatory region sequence-specific DNA binding
PANTHER GO-slim Biological Process: brain development
camera-type eye morphogenesis
negative regulation of transcription by RNA polymerase II
neuron differentiation
positive regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component: nucleus
PANTHER protein class: HMG box transcription factor
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: miRNA binding, DNA binding, DNA-binding transcription factor activity, protein binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, transcription cis-regulatory region binding, DNA-binding transcription activator activity, RNA polymerase II-specific, sequence-specific double-stranded DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete: mesenchyme development, neuroepithelial cell differentiation, positive regulation of translation, negative regulation of cell population proliferation, positive regulation of cell population proliferation, nervous system development, positive regulation of gamma-delta T cell differentiation, positive regulation of myoblast differentiation, positive regulation of transcription by RNA polymerase II, spinal cord development, negative regulation of transcription by RNA polymerase II, sympathetic nervous system development, heart development, response to hypoxia, positive regulation of DNA-templated transcription, cellular response to glucose stimulus, somatic stem cell population maintenance, ascending aorta morphogenesis, negative regulation of protein ubiquitination, positive regulation of insulin secretion, endocrine pancreas development, regulation of DNA damage response, signal transduction by p53 class mediator, kidney morphogenesis, neuron differentiation, mitral valve morphogenesis, hematopoietic stem cell homeostasis, positive regulation of canonical Wnt signaling pathway, regulation of DNA-templated transcription, brain development, glial cell development, ventricular septum morphogenesis, atrial septum primum morphogenesis, noradrenergic neuron differentiation, T cell differentiation, cardiac right ventricle morphogenesis, camera-type eye morphogenesis, regulation of protein stability, pro-B cell differentiation, negative regulation of myoblast differentiation, glucose homeostasis, positive regulation of apoptotic process, gene expression, glial cell proliferation, protein stabilization, positive regulation of N-terminal peptidyl-lysine acetylation
GO CC Complete: nucleus, transcription regulator complex, cytoplasm, mitochondrion, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Signaling by WNT, Deactivation of the beta-catenin transactivating complex, Signal Transduction, TCF dependent signaling in response to WNT

Orthologs