PANTHER Gene Information   
Gene Symbol(s): Sod2
Organism: Mus musculus
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Gene Name: Superoxide dismutase [Mn], mitochondrial
Gene ID: MGI:98352
Protein ID: P09671
Persistent Id: PTN000150095
Alternate Ids:
ENSMUSG00000006818(Ensembl) 17390379(GI)
Q64670(AltAccession) BAB28183(EMBL-CDS)
MGI:98352(MGI) SODM_MOUSE(UniProtKB-ID)
Sod-2(Synonym) X04972(EMBL)
20656(GeneID) ENSMUST00000007012(Ensembl_TRS)
Sod2(Symbol) ENSMUSP00000007012(Ensembl_PRO)
NM_013671(refSeq) 1.15.1.1(EC)
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PANTHER Classification
PANTHER Family: SUPEROXIDE DISMUTASE 2 (PTHR11404)
PANTHER Subfamily: SUPEROXIDE DISMUTASE [MN], MITOCHONDRIAL (PTHR11404:SF6)  
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class: oxidoreductase
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: oxygen binding, DNA binding, identical protein binding, protein binding, oxidoreductase activity, manganese ion binding, superoxide dismutase activity, enzyme binding
GO BP Complete: response to hyperoxia, positive regulation of vascular associated smooth muscle cell apoptotic process, post-embryonic development, response to axon injury, negative regulation of membrane hyperpolarization, response to hypoxia, protein homotetramerization, regulation of mitochondrial membrane potential, regulation of catalytic activity, intracellular oxygen homeostasis, response to gamma radiation, response to electrical stimulus, response to silicon dioxide, intrinsic apoptotic signaling pathway in response to oxidative stress, intrinsic apoptotic signaling pathway in response to DNA damage, response to superoxide, response to hydrogen peroxide, response to reactive oxygen species, negative regulation of vascular associated smooth muscle cell proliferation, acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure, hydrogen peroxide metabolic process, cellular response to ethanol, superoxide metabolic process, removal of superoxide radicals, erythrophore differentiation, response to magnetism, release of cytochrome c from mitochondria, response to selenium ion, response to isolation stress, response to activity, response to immobilization stress, response to nutrient levels, positive regulation of cell migration, response to manganese ion, positive regulation of nitric oxide biosynthetic process, response to zinc ion, multicellular organismal-level iron ion homeostasis, negative regulation of cell population proliferation, hemopoiesis, negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway, respiratory electron transport chain, detection of oxygen, response to xenobiotic stimulus, vasodilation, superoxide anion generation, negative regulation of neuron apoptotic process, response to oxidative stress, heart development, locomotory behavior, apoptotic mitochondrial changes, negative regulation of fibroblast proliferation, liver development, response to L-ascorbic acid, negative regulation of fat cell differentiation, response to cadmium ion, positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching, neuron development, regulation of blood pressure, mitochondrion organization, regulation of transcription by RNA polymerase II, positive regulation of hydrogen peroxide biosynthetic process, glutathione metabolic process, negative regulation of apoptotic process, cellular response to oxidative stress, response to lipopolysaccharide, hydrogen peroxide biosynthetic process
GO CC Complete: myelin sheath, mitochondrial matrix, mitochondrion, mitochondrial inner membrane, mitochondrial nucleoid
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Cellular responses to stimuli, Transcriptional activation of mitochondrial biogenesis, Mitochondrial biogenesis, Cellular response to chemical stress, Organelle biogenesis and maintenance, Cellular responses to stress, Detoxification of Reactive Oxygen Species

Orthologs