PANTHER Gene Information   
Gene Symbol(s): Ccl5
Organism: Mus musculus
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Gene Name: C-C motif chemokine 5
Gene ID: MGI:98262
Protein ID: P30882
Persistent Id: PTN000245838
Alternate Ids:
U02298(EMBL) 548926(GI)
CCL5_MOUSE(UniProtKB-ID) NP_038681(refSeq)
AAC17511(EMBL-CDS) MGI:98262(MGI)
Scya5(Synonym) Ccl5(Symbol)
20304(GeneID) ENSMUSP00000039600(Ensembl_PRO)
ENSMUSG00000035042(Ensembl) ENSMUST00000035938(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: SMALL INDUCIBLE CYTOKINE A (PTHR12015)
PANTHER Subfamily: C-C MOTIF CHEMOKINE 5 (PTHR12015:SF170)  
PANTHER GO-slim Molecular Function: cytokine activity
chemokine receptor binding
PANTHER GO-slim Biological Process: granulocyte migration
positive regulation of GTPase activity
inflammatory response
G protein-coupled receptor signaling pathway
antimicrobial humoral immune response mediated by antimicrobial peptide
positive regulation of cell migration
leukocyte chemotaxis
cytokine-mediated signaling pathway
PANTHER GO-slim Cellular Component: extracellular space
PANTHER protein class: cytokine
Pathway Categories: Inflammation mediated by chemokine and cytokine signaling pathway
   Chemokine

GO MF Complete: chemokine receptor antagonist activity, identical protein binding, protein homodimerization activity, chemoattractant activity, protein kinase activity, heparin binding, chemokine activity, chemokine receptor binding, phosphatidylinositol-4,5-bisphosphate phospholipase C activity, CCR1 chemokine receptor binding, CCR chemokine receptor binding, receptor signaling protein tyrosine kinase activator activity, phospholipase activator activity, CCR5 chemokine receptor binding
GO BP Complete: positive regulation of homotypic cell-cell adhesion, positive chemotaxis, positive regulation of receptor signaling pathway via STAT, positive regulation of calcium ion transport, regulation of programmed cell death, positive regulation of tyrosine phosphorylation of STAT protein, exocytosis, response to toxic substance, positive regulation of angiogenesis, regulation of insulin secretion, inflammatory response, epithelial cell proliferation, lymphocyte chemotaxis, eosinophil chemotaxis, negative regulation of macrophage apoptotic process, positive regulation of TOR signaling, positive regulation of epithelial cell proliferation, G protein-coupled receptor signaling pathway, positive regulation of monocyte chemotaxis, response to type II interferon, cell-cell signaling, positive regulation of T cell proliferation, positive regulation of mast cell chemotaxis, antimicrobial humoral immune response mediated by antimicrobial peptide, cellular response to virus, positive regulation of T cell migration, negative regulation of T cell apoptotic process, positive regulation of gene expression, positive regulation of T cell chemotaxis, positive regulation of T cell apoptotic process, activation of phospholipase D activity, positive regulation of fever generation, positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction, positive regulation of cell migration, pseudopodium assembly, response to tumor necrosis factor, response to cytokine, neutrophil activation, negative regulation by host of viral transcription, positive regulation of biosynthetic process, positive regulation of neuron differentiation, positive regulation of cell adhesion, leukocyte cell-cell adhesion, negative regulation of G protein-coupled receptor signaling pathway, positive regulation of G protein-coupled receptor signaling pathway, positive regulation of smooth muscle cell proliferation, positive regulation of osteoclast differentiation, negative regulation of chemokine-mediated signaling pathway, calcium ion transport, positive regulation of macrophage chemotaxis, cellular response to tumor necrosis factor, positive regulation of smooth muscle cell migration, negative regulation of viral genome replication, positive regulation of cell-cell adhesion mediated by integrin, positive regulation of phosphorylation, cellular response to fibroblast growth factor stimulus, positive regulation of defense response to virus by host, intracellular calcium ion homeostasis, positive regulation of natural killer cell chemotaxis, chemokine-mediated signaling pathway, cellular response to interleukin-1, positive regulation of chemokine (C-X-C motif) ligand 2 production, cellular response to type II interferon, T-helper 1 cell diapedesis, regulation of T cell activation, chemokine (C-C motif) ligand 5 signaling pathway
GO CC Complete: extracellular space, cytoplasm
Reactome Pathways: GPCR ligand binding, G alpha (i) signalling events, Chemokine receptors bind chemokines, Signal Transduction, Peptide ligand-binding receptors, GPCR downstream signalling, Class A/1 (Rhodopsin-like receptors), Signaling by GPCR