PANTHER Gene Information

Gene Symbol(s):

Rap2a

Organism:

Mus musculus

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Gene Name:

Ras-related protein Rap-2a

Gene ID:

MGI:97855

Protein ID:

Q80ZJ1

Persistent Id:

PTN000631660

Alternate Ids:

BC049084(EMBL)	AAH53003(EMBL-CDS)
Rap2a(Symbol)	RAP2A(Synonym)
MGI:97855(MGI)	76108(GeneID)
RAP2A_MOUSE(UniProtKB-ID)	55777982(GI)
Q810A2(AltAccession)	ENSMUSG00000051615(Ensembl)
3.6.5.2 {ECO:0000250\|UniProtKB:P10114}(EC)
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PANTHER Classification

PANTHER Family:	RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY (PTHR24070)
PANTHER Subfamily:	RAS-RELATED PROTEIN RAP-2A (PTHR24070:SF221)
PANTHER GO-slim Molecular Function:	carbohydrate derivative binding anion binding GTPase activity nucleotide binding
PANTHER GO-slim Biological Process:	negative regulation of cell migration small GTPase-mediated signal transduction
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	small GTPase

Pathway Categories:

Integrin signalling pathway

Ras associated protein 1

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	magnesium ion binding, GTP binding, protein binding, GTPase activity, G protein activity, GDP binding
GO BP Complete:	protein localization, regulation of postsynaptic membrane neurotransmitter receptor levels, regulation of dendrite morphogenesis, regulation of JNK cascade, establishment of protein localization, positive regulation of protein autophosphorylation, positive regulation of protein phosphorylation, microvillus assembly, cellular response to xenobiotic stimulus, Rap protein signal transduction, actin cytoskeleton organization, negative regulation of cell migration, regulation of synapse assembly, protein localization to plasma membrane
GO CC Complete:	Schaffer collateral - CA1 synapse, membrane, cytosol, recycling endosome, midbody, synapse, recycling endosome membrane, synaptic membrane, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9861\|UniProtKB=P10114	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000005983.6\|UniProtKB=H2Q7Q7	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000039196.1\|UniProtKB=A0A2I2YVG8	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000062318.1\|UniProtKB=F7GCR4	Macaca mulatta	LDO
RAT\|RGD=620590\|UniProtKB=A0A0G2JTW1	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000020412.3\|UniProtKB=E1BNQ3	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000039812.3\|UniProtKB=A0A286ZUT3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000033905.2\|UniProtKB=A0A9L0SXX7	Equus caballus	LDO
HORSE\|Ensembl=ENSECAG00000051427.1\|UniProtKB=A0A9L0TCN0	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000044348.2\|UniProtKB=A0A2I2UK19	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845019567.1\|UniProtKB=A0A8I3NYQ1	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000043319.1\|UniProtKB=A0A5F8G1X1	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000047686.1\|UniProtKB=A0A5F8G780	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000042125.1\|UniProtKB=A0A6I8PC07	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010017228.1\|UniProtKB=A0A8V0Z084	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010005237.1\|UniProtKB=E1BQI2	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000041592.1\|UniProtKB=A0A803TZK0	Anolis carolinensis	LDO
XENLA\|Gene=LOC100505442\|UniProtKB=Q6NRU1	Xenopus laevis	O
XENLA\|Gene=rap2a.S\|UniProtKB=Q7ZX67	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-479951\|UniProtKB=Q28GA4	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000005426.2\|UniProtKB=H2LLC1	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000023558.1\|UniProtKB=A0A3B3I3L6	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-090312-116\|UniProtKB=B8JIV0	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-121018-1\|UniProtKB=E7F144	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000003615.1\|UniProtKB=W5M7C9	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000016915.2\|UniProtKB=F6Q349	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000001232.3\|UniProtKB=F6SBR0	Ciona intestinalis	O
BRAFL\|Gene=LOC118417903\|UniProtKB=A0A9J7LB66	Branchiostoma floridae	O
BRAFL\|Gene=LOC118426848\|UniProtKB=A0A9J7N403	Branchiostoma floridae	O
BRAFL\|Gene=LOC118426813\|UniProtKB=A0A9J7M0R3	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC753090\|UniProtKB=A0A7M7HKA0	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00008382\|UniProtKB=Q18957	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG12536\|UniProtKB=A8XG01	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00004309\|UniProtKB=O01312	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00004308\|UniProtKB=O17599	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00032680\|UniProtKB=A8XDJ3	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00096817\|UniProtKB=A0A2A6CB88	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00102177\|UniProtKB=A0A2A6CSY2	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0283666\|UniProtKB=O96692	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP004769\|UniProtKB=Q7PMT0	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC001713\|UniProtKB=D6W8A5	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_318262\|UniProtKB=E9GIA3	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG156884\|UniProtKB=T1EM26	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG154062\|UniProtKB=T1ELD6	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g16994\|UniProtKB=A7SI57	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g204358\|UniProtKB=A7RZ86	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g83753\|UniProtKB=A7RJN8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g119290\|UniProtKB=A7SI58	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g69635\|UniProtKB=A8DW02	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g195002\|UniProtKB=A7SZN4	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g139295\|UniProtKB=A7SZM4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g72442\|UniProtKB=A7S8C2	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g151852\|UniProtKB=A7T9Z6	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG56973\|UniProtKB=B3RX28	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG49712\|UniProtKB=B3RLY8	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_2929\|UniProtKB=A9UPR8	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_37080\|UniProtKB=A9UZG5	Monosiga brevicollis	O
YEAST\|SGD=S000003384\|UniProtKB=P13856	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ACR066C\|UniProtKB=Q75C51	Eremothecium gossypii	O
EREGS\|EnsemblGenome=AGOS_AFR464W\|UniProtKB=Q752V9	Eremothecium gossypii	O
CANAL\|CGD=CAL0000199219\|UniProtKB=A0A1D8PS50	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_F23177g\|UniProtKB=Q6C0N5	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_04685\|UniProtKB=C8VAZ3	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_5G08950\|UniProtKB=Q4WUM2	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU02167\|UniProtKB=Q7SEQ0	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_03294\|UniProtKB=A7EDA4	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_09547\|UniProtKB=Q0UFB7	Phaeosphaeria nodorum	O
USTMA\|EnsemblGenome=UMAG_11909\|UniProtKB=A0A0D1C7L9	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_12740\|UniProtKB=E3KRS4	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_23334\|UniProtKB=F4NYQ1	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_004860\|UniProtKB=C4M081	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_058090\|UniProtKB=C4M8B0	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_109840\|UniProtKB=C4M3K3	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=EHI_049030\|UniProtKB=B1N4V4	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0272857\|UniProtKB=Q86L51	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_26434\|UniProtKB=F0Z8S2	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0270340\|UniProtKB=Q55BW0	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_74092\|UniProtKB=F0Z6W4	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0291237\|UniProtKB=P18613	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_59134\|UniProtKB=F1A4I5	Dictyostelium purpureum	O
TRYB2\|Gene_ORFName=Tb11.02.3850\|UniProtKB=Q385G5	Trypanosoma brucei	O
TRIV3\|Gene_ORFName=TVAG_121390\|UniProtKB=A2G0V9	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_202040\|UniProtKB=A2DWM5	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_404090\|UniProtKB=A2EGF8	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_580280\|UniProtKB=A2G856	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_533910\|UniProtKB=A2G1N8	Trichomonas vaginalis	O
PARTE\|EnsemblGenome=GSPATT00027953001\|UniProtKB=A0BEF3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00014016001\|UniProtKB=A0D7N2	Paramecium tetraurelia	O
PHYRM\|Gene=H3GA69_PHYRM\|UniProtKB=H3GA69	Phytophthora ramorum	O