PANTHER Gene Information

Gene Symbol(s):

Prodh

Organism:

Mus musculus

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Gene Name:

Proline dehydrogenase 1, mitochondrial

Gene ID:

MGI:97770

Protein ID:

Q9WU79

Persistent Id:

PTN000357797

Alternate Ids:

19125(GeneID)	NM_011172(refSeq)
Pro1(Synonym)	ENSMUSP00000003620(Ensembl_PRO)
ENSMUST00000003620(Ensembl_TRS)	Prodh(Symbol)
AAI25328(EMBL-CDS)	AC087064(EMBL)
6685799(GI)	ENSMUSG00000003526(Ensembl)
A0JLW6(AltAccession)	1.5.5.2(EC)
MGI:97770(MGI)	PROD_MOUSE(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	PROLINE OXIDASE (PTHR13914)
PANTHER Subfamily:	PROLINE DEHYDROGENASE 1, MITOCHONDRIAL (PTHR13914:SF0)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	oxidase

Pathway Categories:

Huntington disease

Proline oxidase

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	FAD binding, proline dehydrogenase activity, amino acid binding
GO BP Complete:	regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway, proline catabolic process to glutamate
GO CC Complete:	mitochondrial matrix, intracellular membrane-bounded organelle, mitochondrion, mitochondrial inner membrane, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Metabolism, Proline catabolism, Metabolism of amino acids and derivatives

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9453\|UniProtKB=O43272	Homo sapiens	LDO
RAT\|RGD=1590932\|UniProtKB=F1MAR6	Rattus norvegicus	LDO
BOVIN\|Gene=PRODH\|UniProtKB=Q148G5	Bos taurus	LDO
BOVIN\|Ensembl=ENSBTAG00000047676.2\|UniProtKB=G3N3Y2	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000033787.2\|UniProtKB=M3V806	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000026825.4\|UniProtKB=H9H021	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000028790.4\|UniProtKB=M3XDZ0	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845026581.1\|UniProtKB=A0A8I3PZC0	Canis lupus familiaris	LDO
ORNAN\|Ensembl=ENSOANG00000008974.3\|UniProtKB=F7G2D5	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010000145.1\|UniProtKB=F1NRZ9	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000010604.4\|UniProtKB=H9GGM4	Anolis carolinensis	LDO
XENLA\|Gene=prodh.L\|UniProtKB=Q4V7V6	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5866533\|UniProtKB=A0A6I8SWR5	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000000830.2\|UniProtKB=H2L5F0	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000008119.2\|UniProtKB=H2LVQ3	Oryzias latipes	LDO
DANRE\|Gene=prodhb\|UniProtKB=A0A8M6Z0Q4	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-041008-73\|UniProtKB=E7FFM5	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000003730.1\|UniProtKB=W5M7T8	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118426273\|UniProtKB=A0A9J7LZS0	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC583929\|UniProtKB=A0A7M7PAG3	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00007197\|UniProtKB=O45228	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00040963\|UniProtKB=A8Y253	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00277116\|UniProtKB=A0A2A6CBI3	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0003423\|UniProtKB=Q04499	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP003860\|UniProtKB=Q7QFT0	Anopheles gambiae	LDO
ANOGA\|EnsemblGenome=AGAP012718\|UniProtKB=Q7QL50	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC006024\|UniProtKB=D6WUI6	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_204241\|UniProtKB=E9HR55	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_207386\|UniProtKB=E9FYN6	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW000787\|UniProtKB=B7P4N1	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG108980\|UniProtKB=T1EEP6	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG82857\|UniProtKB=T1G4X5	helobdella robusta	LDO
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g109074\|UniProtKB=A7S8U9	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g115782\|UniProtKB=A7SEU7	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG1010\|UniProtKB=B3S1L1	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_14774\|UniProtKB=A9UR51	Monosiga brevicollis	LDO
YEAST\|SGD=S000004132\|UniProtKB=P09368	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AGL165W\|UniProtKB=Q750V4	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000197353\|UniProtKB=A0A1D8PNH4	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_B09625g\|UniProtKB=Q6CF75	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_11221\|UniProtKB=C8VR43	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_3G02300\|UniProtKB=Q4WFG2	Neosartorya fumigata	O
SCLS1\|EnsemblGenome=SS1G_03682\|UniProtKB=A7EEE2	Sclerotinia sclerotiorum	O
EMENI\|EnsemblGenome=ANIA_01731\|UniProtKB=Q5BCJ9	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_6G08760\|UniProtKB=Q4WMT7	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU02936\|UniProtKB=Q7SHG8	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_12075\|UniProtKB=A7F2C8	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_00048\|UniProtKB=Q0V7G6	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_09277\|UniProtKB=Q5AR03	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_06026\|UniProtKB=Q5B0A4	Emericella nidulans	LDO
PHANO\|EnsemblGenome=SNOG_07578\|UniProtKB=Q0UKY6	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPCC70.03c\|UniProtKB=O74524	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_01903\|UniProtKB=B6JZ77	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNE04860\|UniProtKB=Q5KG50	Cryptococcus neoformans	O
CRYNJ\|EnsemblGenome=CNE04870\|UniProtKB=Q5KG49	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_00030\|UniProtKB=A0A0D1CF11	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_08459\|UniProtKB=E3KDR7	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_2340\|UniProtKB=F4P3L2	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0275669\|UniProtKB=Q86H28	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_37322\|UniProtKB=F0ZSP4	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_26_1610\|UniProtKB=Q4Q933	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb927.7.210\|UniProtKB=Q57U33	Trypanosoma brucei	LDO
PARTE\|EnsemblGenome=GSPATT00025595001\|UniProtKB=A0EC42	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00030829001\|UniProtKB=A0BNS3	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_32485\|UniProtKB=B8BVL5	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3G771_PHYRM\|UniProtKB=H3G771	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_01g036850v5\|UniProtKB=A0A2K3E796	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_16g648350v5\|UniProtKB=A0A2K3CSN7	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00006p00263490\|UniProtKB=W1PD27	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_25G00170\|UniProtKB=A0A0K9PHF5	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_16G00580\|UniProtKB=A0A0K9PSQ0	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma11_g19620\|UniProtKB=A0A804L9N7	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma11_g19610\|UniProtKB=A0A804L9N6	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma05_g23060\|UniProtKB=A0A804J7L1	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_035342mg\|UniProtKB=K4A8Y6	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3001G304700\|UniProtKB=A0A1B6QM18	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb391720\|UniProtKB=B6STU5	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb022980\|UniProtKB=A0A1D6K864	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os10g0550900\|UniProtKB=Q336U3	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g32880v3\|UniProtKB=I1I600	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0055890\|UniProtKB=F2E6C0	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS1D02G212400\|UniProtKB=A0A3B5ZW43	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1A02G209100\|UniProtKB=A0A3B5XZX9	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1B02G223300\|UniProtKB=A0A3B5YXP0	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_005815\|UniProtKB=A0A1U8A9R3	Nelumbo nucifera	O
NELNU\|Gene=LOC104597806\|UniProtKB=A0A1U7ZTZ2	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110786840\|UniProtKB=A0A9R0ID75	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr09g0399631\|UniProtKB=A0A251TX37	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr15g0712341\|UniProtKB=A0A251SK67	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C400223920\|UniProtKB=A0A9R1VVC8	Lactuca sativa	O
HELAN\|EnsemblGenome=HanXRQr2_Chr14g0652341\|UniProtKB=A0A251SMD9	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C200081960\|UniProtKB=A0A9R1XR85	Lactuca sativa	O
HELAN\|EnsemblGenome=HanXRQr2_Chr12g0559381\|UniProtKB=A0A251T832	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C300136850\|UniProtKB=A0A9R1W583	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a004942mg\|UniProtKB=A0A022RW45	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a003788mg\|UniProtKB=A0A022RKE0	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_06801\|UniProtKB=A0A1U8FBD0	Capsicum annuum	O
SOLLC\|EnsemblGenome=Solyc02g089630.3\|UniProtKB=A0A3Q7FBC8	Solanum lycopersicum	O
TOBAC\|Gene=cig1\|UniProtKB=Q8W415	Nicotiana tabacum	O
TOBAC\|Gene=LOC107764952\|UniProtKB=A0A1S3XGE9	Nicotiana tabacum	O
CAPAN\|EnsemblGenome=T459_06800\|UniProtKB=A0A2G3ABS3	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400010050\|UniProtKB=M1AMK2	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc02g089620.3\|UniProtKB=A0A3Q7F9T1	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107790219\|UniProtKB=A0A1S3ZT73	Nicotiana tabacum	O
TOBAC\|Gene=LOC107783527\|UniProtKB=A0A1S3Z6G9	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi14g01283\|UniProtKB=D7SMI9	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_J01449\|UniProtKB=A0A059AE59	Eucalyptus grandis	LDO
BRACM\|EnsemblGenome=Bra028202\|UniProtKB=M4EHD7	Brassica campestris	O
ARATH\|TAIR=locus=2166645\|UniProtKB=Q6NKX1	Arabidopsis thaliana	O
BRANA\|Gene_ORFName=GSBRNA2T00009793001\|UniProtKB=A0A078G092	Brassica napus	O
BRACM\|EnsemblGenome=Bra036196\|UniProtKB=M4F540	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_C02P56110.1\|UniProtKB=A0A078HDI3	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A02P37110.1\|UniProtKB=A0A078I4V0	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra025421\|UniProtKB=A0A3P5YMJ7	Brassica campestris	O
BRACM\|EnsemblGenome=Bra020731\|UniProtKB=M4DW37	Brassica campestris	LDO
ARATH\|TAIR=locus=2089706\|UniProtKB=P92983	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107962246\|UniProtKB=A0A1U8PUL3	Gossypium hirsutum	O
GOSHI\|Gene=LOC107954821\|UniProtKB=A0A1U8P4G9	Gossypium hirsutum	O
GOSHI\|Gene=LOC107912896\|UniProtKB=V9LU17	Gossypium hirsutum	O
GOSHI\|Gene=LOC107916714\|UniProtKB=A0A1U8KG93	Gossypium hirsutum	O
GOSHI\|Gene=LOC107895437\|UniProtKB=A0A1U8IK14	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_019628\|UniProtKB=A0A061EI66	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g042033mg\|UniProtKB=A0A067EUQ2	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_017G109300v3\|UniProtKB=U5FM30	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_004G106400v3\|UniProtKB=A0A2K2AST5	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_02G063900\|UniProtKB=V9M5A2	Manihot esculenta	LDO
SOYBN\|EnsemblGenome=GLYMA_19G043000\|UniProtKB=K7MWG9	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_19G042900\|UniProtKB=I1N6L0	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_13G049700\|UniProtKB=K7LXR0	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_6g016635\|UniProtKB=A0A072U662	Medicago truncatula	LDO
MEDTR\|EnsemblGenome=MTR_6g016650\|UniProtKB=A0A072U7A1	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_6g016640\|UniProtKB=A0A072UHG7	Medicago truncatula	LDO
SOYBN\|EnsemblGenome=GLYMA_08G255900\|UniProtKB=I1KWN9	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_18G278900\|UniProtKB=I1N4V3	Glycine max	O
MEDTR\|EnsemblGenome=MTR_7g020820\|UniProtKB=G7KSV1	Medicago truncatula	O
JUGRE\|Gene=LOC109001827\|UniProtKB=A0A6P9F2R9	Juglans regia	O
JUGRE\|EnsemblGenome=Jr01_01510\|UniProtKB=A0A2I4FR57	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_5G643300\|UniProtKB=A0A0A0KXN4	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_3G243500\|UniProtKB=M5X4N6	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_100996\|UniProtKB=D8RTS4	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_236139\|UniProtKB=D8T5D6	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c5_9640\|UniProtKB=A0A7I4DW07	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c17_4560\|UniProtKB=A0A2K1J2N1	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c16_2800\|UniProtKB=A0A2K1J6X0	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0001s0130\|UniProtKB=A0A2R6XVE3	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_003580130\|UniProtKB=A0A1Y1I9A2	Klebsormidium nitens	LDO
HALSA\|EnsemblGenome=VNG_2120G\|UniProtKB=Q9HNG0	Halobacterium salinarum	LDO
STRCO\|Gene_OrderedLocusName=SCO5519\|UniProtKB=Q9Z560	Streptomyces coelicolor	LDO
MYCTU\|Gene_OrderedLocusName=Rv1188\|UniProtKB=O50444	Mycobacterium tuberculosis	LDO
STAA8\|EnsemblGenome=SAOUHSC_01884\|UniProtKB=Q2FXG3	Staphylococcus aureus	LDO
BACSU\|EnsemblGenome=BSU_03200\|UniProtKB=P94390	Bacillus subtilis	O
BACSU\|EnsemblGenome=BSU_32850\|UniProtKB=O32179	Bacillus subtilis	LDO
BACCR\|EnsemblGenome=BC_5006\|UniProtKB=Q815W8	Bacillus cereus	LDO
DEIRA\|EnsemblGenome=DR_0814\|UniProtKB=Q9RW55	Deinococcus radiodurans	LDO