PANTHER Gene Information   
Gene Symbol(s): Abcb1a
Organism: Mus musculus
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Gene Name: ATP-dependent translocase ABCB1
Gene ID: MGI:97570
Protein ID: P21447
Persistent Id: PTN000657251
Alternate Ids:
18671(GeneID) M33581(EMBL)
CHEMBL2573(ChEMBL) ENSMUSP00000041204(Ensembl_PRO)
Abcb1a{ECO:0000312|MGI:MGI:97570}(Symbol) Phospholipid transporter ABCB1 {ECO:0000305}(Synonym)
AAA03243(EMBL-CDS) ENSMUST00000047753(Ensembl_TRS)
148682730(GI) ENSMUSG00000040584(Ensembl)
NP_035206(refSeq) 7.6.2.2 {ECO:0000250|UniProtKB:P08183}(EC)
MDR1A_MOUSE(UniProtKB-ID) Q5I1Y5(AltAccession)
MGI:97570(MGI)
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PANTHER Classification
PANTHER Family: ATP-BINDING CASSETTE SUB-FAMILY B (PTHR24221)
PANTHER Subfamily: ATP-DEPENDENT TRANSLOCASE ABCB1 (PTHR24221:SF251)  
PANTHER GO-slim Molecular Function: ATPase-coupled transmembrane transporter activity
PANTHER GO-slim Biological Process: transmembrane transport
PANTHER GO-slim Cellular Component: apical plasma membrane
PANTHER protein class: ATP-binding cassette (ABC) transporter
Pathway Categories: No pathway information available
GO MF Complete: ATP hydrolysis activity, xenobiotic transmembrane transporter activity, ATPase-coupled transmembrane transporter activity, phosphatidylethanolamine flippase activity, efflux transmembrane transporter activity, transmembrane transporter activity, phosphatidylcholine floppase activity, ABC-type xenobiotic transporter activity, carboxylic acid transmembrane transporter activity, ATP binding, ceramide floppase activity, ubiquitin protein ligase binding, floppase activity
GO BP Complete: protein localization to bicellular tight junction, response to progesterone, negative regulation of sensory perception of pain, response to hypoxia, xenobiotic detoxification by transmembrane export across the plasma membrane, xenobiotic transport across blood-brain barrier, phospholipid translocation, establishment of blood-retinal barrier, response to antineoplastic agent, export across plasma membrane, maintenance of blood-brain barrier, cellular response to external biotic stimulus, response to codeine, cellular response to L-glutamate, cellular response to borneol, cellular response to nonylphenol, carboxylic acid transmembrane transport, response to cyclosporin A, response to quercetin, ceramide translocation, terpenoid transport, circadian rhythm, response to glycoside, regulation of response to osmotic stress, hormone transport, gene expression, transepithelial transport, response to glucagon, response to vitamin D, regulation of intestinal absorption, lactation, response to xenobiotic stimulus, placenta development, intestinal absorption, cellular response to estradiol stimulus, G2/M transition of mitotic cell cycle, response to thyroxine, cellular hyperosmotic salinity response, stem cell proliferation, regulation of chloride transport, response to alcohol, cellular response to alkaloid, cellular response to tumor necrosis factor, cellular response to antibiotic, positive regulation of response to drug, cellular response to mycotoxin, female pregnancy, establishment of blood-brain barrier, response to cadmium ion, positive regulation of establishment of Sertoli cell barrier, daunorubicin transport, positive regulation of anion channel activity, cellular response to lipopolysaccharide, response to vitamin A, cellular response to dexamethasone stimulus
GO CC Complete: intercellular canaliculus, brush border membrane, cytoplasm, membrane, plasma membrane, apical plasma membrane, cell surface
Reactome Pathways: Transport of small molecules, ABC-family proteins mediated transport, Drug ADME, Atorvastatin ADME, Prednisone ADME