PANTHER Gene Information

Gene Symbol(s):

Oas1b

Organism:

Mus musculus

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Gene Name:

Inactive 2'-5'-oligoadenylate synthase 1B

Gene ID:

MGI:97430

Protein ID:

Q60856

Persistent Id:

PTN001679813

Alternate Ids:

NM_001083925(refSeq)	A8YPE9(AltAccession)
AF418004(EMBL)	159031205(GI)
23961(GeneID)	OAS1B(Synonym)
MGI:97430(MGI)	AAM47542(EMBL-CDS)
OAS1B_MOUSE(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	2-5 OLIGOADENYLATE SYNTHETASE (PTHR11258)
PANTHER Subfamily:	INACTIVE 2'-5'-OLIGOADENYLATE SYNTHASE 1B (PTHR11258:SF19)
PANTHER GO-slim Molecular Function:	double-stranded RNA binding adenylyltransferase activity
PANTHER GO-slim Biological Process:	negative regulation of biological process defense response to virus regulation of RNA metabolic process regulation of hydrolase activity
PANTHER GO-slim Cellular Component:	cytosol membrane nucleoplasm
PANTHER protein class:	nucleotidyltransferase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	2'-5'-oligoadenylate synthetase activity, protein binding, double-stranded RNA binding
GO BP Complete:	positive regulation of monocyte chemotactic protein-1 production, toll-like receptor 4 signaling pathway, negative regulation of type I interferon-mediated signaling pathway, glucose metabolic process, response to virus, defense response to bacterium, surfactant homeostasis, positive regulation of cellular respiration, type I interferon-mediated signaling pathway, regulation of ribonuclease activity, positive regulation of interferon-beta production, innate immune response, glucose homeostasis, toll-like receptor 3 signaling pathway, defense response to virus, positive regulation of tumor necrosis factor production, negative regulation of chemokine (C-X-C motif) ligand 2 production, negative regulation of IP-10 production, negative regulation of viral genome replication, antiviral innate immune response, cellular response to interferon-alpha, protein complex oligomerization, interleukin-27-mediated signaling pathway, cellular response to interferon-beta
GO CC Complete:	endoplasmic reticulum membrane, nucleus, cytoplasm, mitochondrion, membrane, cytosol, ribosome, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=8086\|UniProtKB=P00973	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000005477.6\|UniProtKB=H2R747	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000008132.3\|UniProtKB=G3SFB1	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000012782.4\|UniProtKB=F7EI59	Macaca mulatta	O
RAT\|RGD=708393\|UniProtKB=Q5BKD0	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000037527.3\|UniProtKB=F1N009	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000053807.1\|UniProtKB=F1N6E0	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000039861.3\|UniProtKB=F1MV66	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000046640.1\|UniProtKB=A0A5G2QIL7	Sus scrofa	O
PIG\|Gene=OAS1\|UniProtKB=Q29599	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000013435.4\|UniProtKB=A0A9L0SI36	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000000318.6\|UniProtKB=M3VUI8	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845021979.1\|UniProtKB=A0A8I3P9W9	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000037008.1\|UniProtKB=A0A5F8GBC6	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000003252.4\|UniProtKB=F6T1N6	Monodelphis domestica	O
CHICK\|Ensembl=ENSGALG00010027634.1\|UniProtKB=A0A8V1A4X0	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000044707.1\|UniProtKB=A0A803TUZ1	Anolis carolinensis	O
CIOIN\|Ensembl=ENSCING00000024111.1\|UniProtKB=H2XUV5	Ciona intestinalis	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_121175\|UniProtKB=C3YPK4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421966\|UniProtKB=A0A9J7LLY4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421963\|UniProtKB=A0A9J7LLZ3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421967\|UniProtKB=A0A9J7LMK7	Branchiostoma floridae	O
BRAFL\|Gene=LOC118432796\|UniProtKB=A0A9J7MGA8	Branchiostoma floridae	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g241602\|UniProtKB=A7RYP1	Nematostella vectensis	O
MONBE\|EnsemblGenome=MONBRDRAFT_39312\|UniProtKB=A9VDN9	Monosiga brevicollis	O
CHLRE\|EnsemblGenome=CHLRE_05g234666v5\|UniProtKB=A0A2K3DSP1	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_13g605386v5\|UniProtKB=A0A2K3D1F3	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_13g605500v5\|UniProtKB=A0A2K3D1F2	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_15g641050v5\|UniProtKB=A0A2K3CWU6	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_13g605600v5\|UniProtKB=A0A2K3D1I0	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_13g605350v5\|UniProtKB=A0A2K3D1D9	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_13g605550v5\|UniProtKB=A0A2K3D1H7	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_06g307700v5\|UniProtKB=A0A2K3DRJ2	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_13g606300v5\|UniProtKB=A0A2K3D1H2	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_13g581700v5\|UniProtKB=A0A2K3D0G1	Chlamydomonas reinhardtii	O