PANTHER Gene Information   
Gene Symbol(s): Mmp9
Organism: Mus musculus
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Gene Name: Matrix metalloproteinase-9
Gene ID: MGI:97011
Protein ID: P41245
Persistent Id: PTN000024263
Alternate Ids:
MGI:97011(MGI) MMP9_MOUSE(UniProtKB-ID)
ENSMUST00000017881(Ensembl_TRS) S67830(EMBL)
Clg4b(Synonym) Mmp9(Symbol)
17395(GeneID) BAA02208(EMBL-CDS)
NM_013599(refSeq) 7305277(GI)
Q06788(AltAccession) ENSMUSP00000017881(Ensembl_PRO)
CHEMBL2214(ChEMBL) 3.4.24.35 {ECO:0000250|UniProtKB:P14780}(EC)
ENSMUSG00000017737(Ensembl)
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PANTHER Classification
PANTHER Family: MATRIX METALLOPROTEINASE (PTHR10201)
PANTHER Subfamily: MATRIX METALLOPROTEINASE-9 (PTHR10201:SF30)  
PANTHER GO-slim Molecular Function: metalloendopeptidase activity
PANTHER GO-slim Biological Process: catabolic process
extracellular matrix organization
PANTHER GO-slim Cellular Component: extracellular space
PANTHER protein class: metalloprotease
Pathway Categories: CCKR signaling map
   MMP9
Alzheimer disease-presenilin pathway
   Matrix metalloprotease
Plasminogen activating cascade
   pro-matrix metalloprotease 9
CCKR signaling map
   MMP9
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: zinc ion binding, identical protein binding, fibronectin binding, endopeptidase activity, serine-type endopeptidase activity, peptidase activity, metalloendopeptidase activity, metallopeptidase activity, protein-containing complex binding
GO BP Complete: positive regulation of epidermal growth factor receptor signaling pathway, response to xenobiotic stimulus, positive regulation of DNA binding, positive regulation of angiogenesis, response to oxidative stress, heart development, skeletal system development, cellular response to UV-A, positive regulation of vascular associated smooth muscle cell proliferation, negative regulation of fibroblast proliferation, macrophage chemotaxis, apoptotic process, positive regulation of synaptic plasticity, cellular response to cadmium ion, negative regulation of epithelial cell differentiation involved in kidney development, positive regulation of keratinocyte migration, negative regulation of intrinsic apoptotic signaling pathway, cell migration, protein catabolic process, positive regulation of receptor binding, positive regulation of release of cytochrome c from mitochondria, response to amyloid-beta, embryo implantation, tissue remodeling, cellular response to cell-matrix adhesion, positive regulation of leukocyte migration, negative regulation of apoptotic process, positive regulation of protein phosphorylation, proteolysis, positive regulation of apoptotic process, extracellular matrix organization, endodermal cell differentiation, negative regulation of cation channel activity, collagen catabolic process, cellular response to reactive oxygen species
GO CC Complete: extracellular space, collagen-containing extracellular matrix, protein-containing complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Immune System, Signaling by Receptor Tyrosine Kinases, Nervous system development, Innate Immune System, Signal Transduction, Axon guidance, Degradation of the extracellular matrix, EPH-Ephrin signaling, EPH-ephrin mediated repulsion of cells, Signaling by Nuclear Receptors, Assembly of collagen fibrils and other multimeric structures, Extracellular matrix organization, ESR-mediated signaling, Extra-nuclear estrogen signaling, Collagen degradation, Signaling by SCF-KIT, Neutrophil degranulation, Activation of Matrix Metalloproteinases, Collagen formation, Developmental Biology

Orthologs