PANTHER Gene Information   
Gene Symbol(s): Il12a
Organism: Mus musculus
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Gene Name: Interleukin-12 subunit alpha
Gene ID: MGI:96539
Protein ID: P43431
Persistent Id: PTN009232591
Alternate Ids:
ENSMUSP00000103446(Ensembl_PRO) Il12a(Symbol)
1170458(GI) Cytotoxic lymphocyte maturation factor 35 kDa subunit(Synonym)
NP_001152896(refSeq) 16159(GeneID)
MGI:96539(MGI) IL12A_MOUSE(UniProtKB-ID)
ENSMUSG00000027776(Ensembl) S82417(EMBL)
ENSMUST00000107816(Ensembl_TRS) BAA09647(EMBL-CDS)
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PANTHER Classification
PANTHER Family: INTERLEUKIN-12 SUBUNIT BETA-RELATED (PTHR48485)
PANTHER Subfamily: INTERLEUKIN-12 SUBUNIT ALPHA (PTHR48485:SF1)  
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:
Pathway Categories: Inflammation mediated by chemokine and cytokine signaling pathway
   Interleukin 2
Interleukin signaling pathway
   Interleukin receptor beta subunit

GO MF Complete: growth factor activity, protein binding, protein heterodimerization activity, interleukin-12 beta subunit binding, interleukin-12 receptor binding, cytokine activity, interleukin-27 binding
GO BP Complete: cell population proliferation, positive regulation of smooth muscle cell apoptotic process, extrinsic apoptotic signaling pathway, negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis, positive regulation of tyrosine phosphorylation of STAT protein, positive regulation of cell adhesion, positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, defense response to protozoan, positive regulation of mononuclear cell proliferation, negative regulation of vascular endothelial growth factor signaling pathway, immune response, type II interferon production, positive regulation of lymphocyte proliferation, positive regulation of type II interferon production, negative regulation of smooth muscle cell proliferation, positive regulation of dendritic cell chemotaxis, negative regulation of interleukin-17 production, cell migration, T-helper 1 cell activation, signal transduction, negative regulation of protein secretion, positive regulation of T cell proliferation, positive regulation of natural killer cell mediated cytotoxicity, cellular response to virus, positive regulation of NK T cell activation, cellular response to lipopolysaccharide, positive regulation of natural killer cell activation, positive regulation of T cell differentiation, T cell proliferation, response to lipopolysaccharide, positive regulation of T cell mediated cytotoxicity, response to UV-B, interleukin-12-mediated signaling pathway, T-helper 1 cell cytokine production
GO CC Complete: endoplasmic reticulum lumen, extracellular space, cytoplasm, endosome lumen, extracellular region, Golgi lumen, interleukin-12 complex, cell surface
Reactome Pathways: Immune System, Interleukin-12 family signaling, Interleukin-12 signaling, Signaling by Interleukins, Interleukin-35 Signalling, Cytokine Signaling in Immune system