PANTHER Gene Information   
Gene Symbol(s): Hsf1
Organism: Mus musculus
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Gene Name: Heat shock factor protein 1
Gene ID: MGI:96238
Protein ID: P38532
Persistent Id: PTN000001079
Alternate Ids:
15499(GeneID) AAH13716(EMBL-CDS)
O70462(AltAccession) 22654251(GI)
MGI:96238(MGI) HSF1_MOUSE(UniProtKB-ID)
Hsf1{ECO:0000312|MGI:MGI:96238}(Symbol) AF059275(EMBL)
CHEMBL5313(ChEMBL) HSF1(Synonym)
ENSMUSG00000022556(Ensembl)
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PANTHER Classification
PANTHER Family: HEAT SHOCK TRANSCRIPTION FACTOR (PTHR10015)
PANTHER Subfamily: HEAT SHOCK FACTOR PROTEIN 1 (PTHR10015:SF274)  
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class: winged helix/forkhead transcription factor
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: protein kinase binding, heat shock protein binding, chromatin DNA binding, identical protein binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, translation elongation factor binding, transcription cis-regulatory region binding, DNA-binding transcription activator activity, RNA polymerase II-specific, sequence-specific DNA binding, DNA-binding transcription repressor activity, RNA polymerase II-specific, chromatin binding, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA binding, promoter-specific chromatin binding, RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding, protein heterodimerization activity, STAT family protein binding, sequence-specific single stranded DNA binding, Hsp90 protein binding, sequence-specific double-stranded DNA binding, general transcription initiation factor binding
GO BP Complete: DNA repair, positive regulation of apoptotic DNA fragmentation, positive regulation of tyrosine phosphorylation of STAT protein, positive regulation of DNA-binding transcription factor activity, positive regulation of stress granule assembly, epithelial cell proliferation, in utero embryonic development, positive regulation of macrophage differentiation, cellular response to unfolded protein, tumor necrosis factor production, response to testosterone, positive regulation of cold-induced thermogenesis, negative regulation of tumor necrosis factor production, cellular response to angiotensin, protein-containing complex assembly, female meiotic nuclear division, positive regulation of inclusion body assembly, cellular response to sodium arsenite, positive regulation of mitotic cell cycle, negative regulation of gene expression, cellular response to gamma radiation, positive regulation of gene expression, negative regulation of epithelial cell proliferation, response to estradiol, negative regulation of cardiac muscle cell apoptotic process, cellular response to diamide, cell population proliferation, negative regulation of double-strand break repair via nonhomologous end joining, regulation of cellular response to heat, regulation of spindle checkpoint, protein phosphorylation, positive regulation of transcription by RNA polymerase II, cellular response to copper ion, embryonic placenta development, positive regulation of multicellular organism growth, negative regulation of transcription by RNA polymerase II, MAPK cascade, cellular response to amino acid stimulus, response to heat, cellular response to estradiol stimulus, cellular response to heat, cellular response to cadmium ion, negative regulation of protein-containing complex assembly, cellular response to hydrogen peroxide, cellular response to radiation, mRNA transport, spermatogenesis, mRNA processing, defense response, embryonic process involved in female pregnancy, negative regulation of inclusion body assembly, regulation of transcription by RNA polymerase II, response to lipopolysaccharide
GO CC Complete: PML body, kinetochore, nucleoplasm, heterochromatin, nucleus, nuclear stress granule, euchromatin, centrosome, perinuclear region of cytoplasm, mitotic spindle pole, cytoplasm, pronucleus, cytosol, protein-containing complex, ribonucleoprotein complex, protein folding chaperone complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Cellular responses to stimuli, HSF1-dependent transactivation, Regulation of HSF1-mediated heat shock response, Attenuation phase, Cellular response to heat stress, HSF1 activation, Cellular responses to stress

Orthologs