PANTHER Gene Information

Gene Symbol(s):

Gdf6

Organism:

Mus musculus

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Gene Name:

Growth_differentiation factor 6

Gene ID:

MGI:95689

Protein ID:

P43028

Persistent Id:

PTN000218425

Alternate Ids:

AJ537425(EMBL)	ENSMUSG00000051279(Ensembl)
GDF6_MOUSE(UniProtKB-ID)	242316(GeneID)
ENSMUST00000057613(Ensembl_TRS)	MGI:95689(MGI)
Gdf6(Symbol)	41529818(GI)
ENSMUSP00000062884(Ensembl_PRO)	Gdf-6(Synonym)
CAD60935(EMBL-CDS)	NP_038554(refSeq)
Q70UT4(AltAccession)
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PANTHER Classification

PANTHER Family:	TGF-BETA FAMILY (PTHR11848)
PANTHER Subfamily:	GROWTH_DIFFERENTIATION FACTOR 6 (PTHR11848:SF43)
PANTHER GO-slim Molecular Function:	cytokine activity
PANTHER GO-slim Biological Process:	BMP signaling pathway
PANTHER GO-slim Cellular Component:	extracellular space
PANTHER protein class:	growth factor

Pathway Categories:

TGF-beta signaling pathway

Transforming growth factor beta

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	growth factor activity, identical protein binding, receptor ligand activity, cytokine activity
GO BP Complete:	positive regulation of neuron differentiation, fat cell differentiation, metanephric tubule development, positive regulation of p38MAPK cascade, activin receptor signaling pathway, metanephros development, positive regulation of DNA-templated transcription, BMP signaling pathway, apoptotic process, retinal cell apoptotic process, positive regulation of chondrocyte differentiation, positive regulation of SMAD protein signal transduction, epithelial cell migration, cell migration involved in metanephros development
GO CC Complete:	extracellular space

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=4221\|UniProtKB=Q6KF10	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000020439.7\|UniProtKB=K7A0F7	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000023170.2\|UniProtKB=G3RVU6	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000065198.1\|UniProtKB=A0A5F7ZJV3	Macaca mulatta	LDO
RAT\|RGD=620104\|UniProtKB=Q6HA10	Rattus norvegicus	LDO
BOVIN\|Gene=GDF6\|UniProtKB=P55106	Bos taurus	LDO
BOVIN\|Ensembl=ENSBTAG00000007687.6\|UniProtKB=A0A452DKC3	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000034943.2\|UniProtKB=A0A287BJW9	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000006902.3\|UniProtKB=F7BWB4	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000042626.2\|UniProtKB=M3XCZ1	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845016606.1\|UniProtKB=A0A8I3NQZ9	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000006980.5\|UniProtKB=A0A5F8HDS8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000049934.1\|UniProtKB=A0A6I8NKE9	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010011423.1\|UniProtKB=A0A1D5P0D7	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000028474.2\|UniProtKB=R4GCR5	Anolis carolinensis	LDO
XENLA\|Gene=gdf6.S\|UniProtKB=Q9W753	Xenopus laevis	O
XENLA\|Gene=LOC108719358\|UniProtKB=A0A1L8FZP6	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-6454242\|UniProtKB=A0A6I8S6B0	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000007867.2\|UniProtKB=H2LUS7	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-980526-442\|UniProtKB=A8E7N9	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000025052.1\|UniProtKB=A0A3B3I4I5	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-980526-373\|UniProtKB=P85857	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000002936.1\|UniProtKB=W5M4Z8	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118417252\|UniProtKB=A0A9J7LB27	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC373488\|UniProtKB=P48970	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=GeneID_373196\|UniProtKB=A0A7M7PRU9	Strongylocentrotus purpuratus	O
DROME\|FlyBase=FBgn0000490\|UniProtKB=P07713	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP007987\|UniProtKB=A0A1S4GXL4	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC008466\|UniProtKB=D2A252	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_347232\|UniProtKB=E9FTU5	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW021631\|UniProtKB=B7Q502	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW023553\|UniProtKB=B7QHX4	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG154960\|UniProtKB=T1ELG7	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g194892\|UniProtKB=A7SZ10	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g168498\|UniProtKB=A7SAY4	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG57057\|UniProtKB=B3S0I2	Trichoplax adhaerens	O