PANTHER Gene Information   
Gene Symbol(s): Xrcc6
Organism: Mus musculus
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Gene Name: X-ray repair cross-complementing protein 6
Gene ID: MGI:95606
Protein ID: P23475
Persistent Id: PTN000288310
Alternate Ids:
14375(GeneID) CTC75(Synonym)
U34878(EMBL) Xrcc6(Symbol)
568991364(GI) BAE27135(EMBL-CDS)
XP_011243758(refSeq) 3.6.4.-(EC)
XRCC6_MOUSE(UniProtKB-ID) Q62382(AltAccession)
MGI:95606(MGI)
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PANTHER Classification
PANTHER Family: KU AUTOANTIGEN DNA HELICASE (PTHR12604)
PANTHER Subfamily: X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 6 (PTHR12604:SF2)  
PANTHER GO-slim Molecular Function: telomeric DNA binding
double-stranded DNA binding
PANTHER GO-slim Biological Process: telomere maintenance
double-strand break repair via nonhomologous end joining
PANTHER GO-slim Cellular Component: nuclear protein-containing complex
PANTHER protein class: DNA helicase
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: ATP hydrolysis activity, ATP-dependent activity, acting on DNA, double-stranded DNA binding, DNA end binding, transcription cis-regulatory region binding, double-stranded telomeric DNA binding, damaged DNA binding, protein-containing complex binding, ATP binding, scaffold protein binding, DNA helicase activity, protein binding, 5'-deoxyribose-5-phosphate lyase activity, telomeric DNA binding, cyclin binding, hydrolase activity
GO BP Complete: V(D)J recombination, recombinational repair, positive regulation of lymphocyte differentiation, telomere maintenance, neurogenesis, double-strand break repair via nonhomologous end joining, DNA damage response, positive regulation of transcription by RNA polymerase II, double-strand break repair, double-strand break repair via classical nonhomologous end joining, regulation of smooth muscle cell proliferation, cellular response to gamma radiation, cellular response to X-ray, negative regulation of DNA-templated transcription, cellular hyperosmotic salinity response, activation of innate immune response, positive regulation of protein kinase activity, positive regulation of DNA-templated transcription, innate immune response, positive regulation of neurogenesis, response to ionizing radiation
GO CC Complete: nucleus, transcription regulator complex, DNA-dependent protein kinase complex, nonhomologous end joining complex, DNA-dependent protein kinase-DNA ligase 4 complex, cytoplasm, protein-DNA complex, protein-containing complex, chromosome, Ku70:Ku80 complex, nucleolus, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Immune System, DNA Repair, Innate Immune System, Neutrophil degranulation, Nonhomologous End-Joining (NHEJ), DNA Double-Strand Break Repair

Orthologs