PANTHER Gene Information   
Gene Symbol(s): Ercc1
Organism: Mus musculus
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Gene Name: DNA excision repair protein ERCC-1
Gene ID: MGI:95412
Protein ID: P07903
Persistent Id: PTN000297537
Alternate Ids:
187960071(GI) X07413(EMBL)
ENSMUSP00000003645(Ensembl_PRO) 13870(GeneID)
Q91VP3(AltAccession) NP_001120796(refSeq)
MGI:95412(MGI) ERCC1_MOUSE(UniProtKB-ID)
EDL23137(EMBL-CDS) ENSMUSG00000003549(Ensembl)
ERCC1(Synonym) ENSMUST00000003645(Ensembl_TRS)
Ercc1(Symbol)
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PANTHER Classification
PANTHER Family: EXCISION REPAIR CROSS-COMPLEMENTING 1 ERCC1 (PTHR12749)
PANTHER Subfamily: DNA EXCISION REPAIR PROTEIN ERCC-1 (PTHR12749:SF0)  
PANTHER GO-slim Molecular Function: damaged DNA binding
single-stranded DNA binding
PANTHER GO-slim Biological Process: mitotic recombination
response to UV
cellular response to light stimulus
DNA repair
PANTHER GO-slim Cellular Component: nucleotide-excision repair complex
PANTHER protein class: endodeoxyribonuclease
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: DNA binding, protein binding, 3' overhang single-stranded DNA endodeoxyribonuclease activity, promoter-specific chromatin binding, TFIID-class transcription factor complex binding, damaged DNA binding, single-stranded DNA endodeoxyribonuclease activity, single-stranded DNA binding
GO BP Complete: cell population proliferation, multicellular organism growth, t-circle formation, DNA repair, post-embryonic hemopoiesis, response to X-ray, male gonad development, replicative senescence, negative regulation of protection from non-homologous end joining at telomere, UV protection, positive regulation of transcription initiation by RNA polymerase II, determination of adult lifespan, interstrand cross-link repair, positive regulation of t-circle formation, nucleotide-excision repair, double-strand break repair via nonhomologous end joining, double-strand break repair, response to oxidative stress, telomeric DNA-containing double minutes formation, negative regulation of telomere maintenance, isotype switching, germ cell development, UV-damage excision repair, spermatogenesis, DNA recombination, insulin-like growth factor receptor signaling pathway, response to nutrient, response to cadmium ion, embryonic organ development, cell development, pyrimidine dimer repair by nucleotide-excision repair, DNA damage response, mitotic recombination, response to sucrose, syncytium formation, oogenesis, chromosome organization, response to immobilization stress
GO CC Complete: nucleotide-excision repair factor 1 complex, chromosome, telomeric region, nucleus, nucleotide-excision repair complex, ERCC4-ERCC1 complex, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: DNA Repair, Formation of Incision Complex in GG-NER, HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA), HDR through Single Strand Annealing (SSA), Homology Directed Repair, Transcription-Coupled Nucleotide Excision Repair (TC-NER), Fanconi Anemia Pathway, Nucleotide Excision Repair, DNA Double-Strand Break Repair, Dual incision in TC-NER, Dual Incision in GG-NER, Global Genome Nucleotide Excision Repair (GG-NER)

Orthologs