PANTHER Gene Information

Gene Symbol(s):

Anpep

Organism:

Mus musculus

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Gene Name:

Aminopeptidase N

Gene ID:

MGI:5000466

Protein ID:

P97449

Persistent Id:

PTN000164435

Alternate Ids:

16790(GeneID)	26252164(GI)
CHEMBL2189140(ChEMBL)	ENSMUSP00000035943(Ensembl_PRO)
Anpep(Symbol)	AP-N(Synonym)
U77083(EMBL)	ENSMUST00000107392(Ensembl_TRS)
ENSMUSG00000039062(Ensembl)	AAH17011(EMBL-CDS)
NM_008486(refSeq)	3.4.11.2 {ECO:0000269\|PubMed:8691132}(EC)
AMPN_MOUSE(UniProtKB-ID)	Q91YH8(AltAccession)
MGI:5000466(MGI)
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PANTHER Classification

PANTHER Family:	PROTEASE M1 ZINC METALLOPROTEASE (PTHR11533)
PANTHER Subfamily:	AMINOPEPTIDASE N (PTHR11533:SF172)
PANTHER GO-slim Molecular Function:	metalloaminopeptidase activity peptide binding zinc ion binding
PANTHER GO-slim Biological Process:	peptide catabolic process proteolysis
PANTHER GO-slim Cellular Component:	extracellular space plasma membrane cytoplasm
PANTHER protein class:	metalloprotease

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	zinc ion binding, alanyl aminopeptidase activity, metalloaminopeptidase activity, aminopeptidase activity, peptide binding, metallopeptidase activity
GO BP Complete:	peptide catabolic process, angiogenesis, proteolysis, cell differentiation, protein processing, angiotensin maturation
GO CC Complete:	extracellular space, brush border membrane, extracellular exosome, cytoplasm, external side of plasma membrane, endoplasmic reticulum-Golgi intermediate compartment, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Immune System, Innate Immune System, Neutrophil degranulation

Orthologs

ID	Organism	Type
HUMAN\|HGNC=500\|UniProtKB=P15144	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000046833.1\|UniProtKB=H2QA26	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000005686.3\|UniProtKB=G3QSE0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000014983.4\|UniProtKB=F6VKN1	Macaca mulatta	LDO
RAT\|RGD=2991\|UniProtKB=P15684	Rattus norvegicus	LDO
BOVIN\|Gene=ANPEP\|UniProtKB=P79098	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000016881.6\|UniProtKB=A0A3Q1MB09	Bos taurus	LDO
PIG\|Gene=ANPEP\|UniProtKB=P15145	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000001849.5\|UniProtKB=A0A5G2QI26	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000047741.1\|UniProtKB=A0A9L0SI61	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000037098.3\|UniProtKB=A0A9L0RFD4	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000036248.2\|UniProtKB=A0A3Q2KXH2	Equus caballus	LDO
FELCA\|Gene=ANPEP\|UniProtKB=P79171	Felis catus	O
FELCA\|Ensembl=ENSFCAG00000008974.6\|UniProtKB=A0A337SS27	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845000639.1\|UniProtKB=A0A8I3MC47	Canis lupus familiaris	LDO
CANLF\|Ensembl=ENSCAFG00805026851\|UniProtKB=P79143	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000019534.4\|UniProtKB=F6UV20	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000000369.3\|UniProtKB=F7CVV6	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010015905.1\|UniProtKB=A0A8V0Z0I1	Gallus gallus	LDO
CHICK\|Gene=ANPEP\|UniProtKB=O57579	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000000512.4\|UniProtKB=H9G484	Anolis carolinensis	LDO
XENLA\|Gene=anpep.S\|UniProtKB=A0A1L8GSN4	Xenopus laevis	O
XENLA\|Gene=anpep.L\|UniProtKB=Q5U4K7	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-981369\|UniProtKB=A0A6I8Q201	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000019272.2\|UniProtKB=A0A3B3IM79	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030131-4781\|UniProtKB=Q1LWJ7	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000014462.1\|UniProtKB=W5NB03	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000014691.2\|UniProtKB=H2MID6	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-141215-4\|UniProtKB=E7F2N2	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-130530-595\|UniProtKB=E7F123	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000014604.2\|UniProtKB=H2MI34	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-131127-23\|UniProtKB=A0A286YAT8	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000029229.1\|UniProtKB=A0A3B3HSW9	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000014593.2\|UniProtKB=H2MI25	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-1253\|UniProtKB=A4FUN4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000014478.1\|UniProtKB=W5NB25	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000022842.1\|UniProtKB=H2XYF3	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000004939.3\|UniProtKB=F6X9G8	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118410873\|UniProtKB=A0A9J7KR64	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC592805\|UniProtKB=A0A7M7HJS4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115918303\|UniProtKB=A0A7M7N1D3	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC590831\|UniProtKB=A0A7M7HHI0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115927263\|UniProtKB=A0A7M7PDR5	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC115923973\|UniProtKB=A0A7M7NT88	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115924707\|UniProtKB=A0A7M7P3I2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115919332\|UniProtKB=A0A7M7MZD8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC578352\|UniProtKB=A0A7M7HJU5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC590806\|UniProtKB=A0A7M7N1F0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC580123\|UniProtKB=A0A7M7NXS1	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC574617\|UniProtKB=A0A7M7NV53	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00020465\|UniProtKB=A5A631	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00039048\|UniProtKB=A8XWQ8	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00013166\|UniProtKB=Q9NAA0	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG20905\|UniProtKB=A8XYX1	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00011587\|UniProtKB=Q22317	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG09515\|UniProtKB=A8X8X6	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00099966\|UniProtKB=A0A2A6BGN8	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0259237\|UniProtKB=Q9VD85	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0051198\|UniProtKB=Q8IN25	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP004860\|UniProtKB=A0A1S4GMD5	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP013146\|UniProtKB=F5HLF1	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP013393\|UniProtKB=A0A1S4HD66	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP004808\|UniProtKB=Q5TPQ5	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP003926\|UniProtKB=Q7Q2B5	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP013255\|UniProtKB=F5HLF3	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP013188\|UniProtKB=F5HLF4	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC001259\|UniProtKB=D6WBA8	Tribolium castaneum	LDO
TRICA\|EnsemblGenome=TC001261\|UniProtKB=D6WBB0	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC001262\|UniProtKB=D6WBB1	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC001260\|UniProtKB=D6WBA9	Tribolium castaneum	LDO
HELRO\|EnsemblGenome=HelroG189234\|UniProtKB=T1FQU4	helobdella robusta	LDO
HELRO\|EnsemblGenome=HelroG163491\|UniProtKB=T1EU46	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG189331\|UniProtKB=T1FQY9	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g207110\|UniProtKB=A7S5H5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g113714\|UniProtKB=A7SCU3	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g105924\|UniProtKB=A7S604	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g246015\|UniProtKB=A7SLF6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g179195\|UniProtKB=A7RL33	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG63983\|UniProtKB=B3S0G8	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG35766\|UniProtKB=B3RU54	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG63531\|UniProtKB=B3RHX6	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG61294\|UniProtKB=B3SAK7	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG36517\|UniProtKB=B3S7T8	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG52305\|UniProtKB=B3RHX5	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG63982\|UniProtKB=B3S0G5	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG57038\|UniProtKB=B3S0G3	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG20166\|UniProtKB=B3RHX4	Trichoplax adhaerens	O
YEAST\|SGD=S000001399\|UniProtKB=P40462	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AER426C\|UniProtKB=Q755U2	Eremothecium gossypii	O
CANAL\|CGD=CAL0000200894\|UniProtKB=A0A1D8PQC4	Candida albicans	O
BATDJ\|Gene_ORFName=BATDEDRAFT_84588\|UniProtKB=F4NSV3	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_34313\|UniProtKB=F4NUU2	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_008380\|UniProtKB=C4M0L4	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0273419\|UniProtKB=Q557I4	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_51094\|UniProtKB=F1A1Z2	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_29_2240\|UniProtKB=E9AE86	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.3.4750\|UniProtKB=Q582Q6	Trypanosoma brucei	O
TRIV3\|Gene_ORFName=TVAG_311790\|UniProtKB=A2EJY5	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_336080\|UniProtKB=A2FN94	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_008880\|UniProtKB=A2FGT3	Trichomonas vaginalis	O
PARTE\|EnsemblGenome=GSPATT00013410001\|UniProtKB=A0D4H7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00019968001\|UniProtKB=A0DTA8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00009510001\|UniProtKB=A0CQU5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00036540001\|UniProtKB=A0CAE3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00009047001\|UniProtKB=A0CPD9	Paramecium tetraurelia	O
CHLRE\|EnsemblGenome=CHLRE_09g402256v5\|UniProtKB=A0A2K3DF50	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_02g076200v5\|UniProtKB=A0A2K3E066	Chlamydomonas reinhardtii	O
NITMS\|EnsemblGenome=Nmar_0957\|UniProtKB=A9A2E2	Nitrosopumilus maritimus	O
SACS2\|EnsemblGenome=SSO2675\|UniProtKB=Q97VF1	Sulfolobus solfataricus	O
SACS2\|EnsemblGenome=SSO2154\|UniProtKB=P95928	Sulfolobus solfataricus	O
STRCO\|Gene_OrderedLocusName=SCO2635\|UniProtKB=Q9L200	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO2018\|UniProtKB=Q9S2I5	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO2643\|UniProtKB=Q9L1Z2	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=Rv2467\|UniProtKB=L7N655	Mycobacterium tuberculosis	O
GLOVI\|Gene=Q7NGU9_GLOVI\|UniProtKB=Q7NGU9	Gloeobacter violaceus	O
SYNY3\|Gene=ape2\|UniProtKB=P74527	Synechocystis	O
LEPIN\|EnsemblGenome=LA_1080\|UniProtKB=Q8F768	Leptospira interrogans	O
RHOBA\|EnsemblGenome=RB5627\|UniProtKB=Q7URJ4	Rhodopirellula baltica	O
DICTD\|EnsemblGenome=Dtur_1564\|UniProtKB=B8E2J4	Dictyoglomus turgidum	O
GEOSL\|EnsemblGenome=GSU3140\|UniProtKB=Q747X5	Geobacter sulfurreducens	O
SHEON\|Gene_OrderedLocusName=SO_1751\|UniProtKB=Q8EG58	Shewanella oneidensis	O
SHEON\|Gene_OrderedLocusName=SO_1059\|UniProtKB=Q8EHZ5	Shewanella oneidensis	O