PANTHER Gene Information

Gene Symbol(s):

Smpd5

Organism:

Mus musculus

View Gene in Tree


Tree	Reduced Tree

Gene Name:

Sphingomyelin phosphodiesterase 5

Gene ID:

MGI:3709877

Protein ID:

D6MZJ6

Persistent Id:

PTN000419019

Alternate Ids:

GU144514(EMBL)	ENSMUST00000163991(Ensembl_TRS)
295389241(GI)	ADG03437(EMBL-CDS)
3.1.4.12 {ECO:0000269\|PubMed:20378533}(EC)	ENSMUSP00000134687(Ensembl_PRO)
MGI:3709877(MGI)	NP_001182466(refSeq)
100503915(GeneID)	NSMA5_MOUSE(UniProtKB-ID)
ENSMUSG00000071724(Ensembl)	NSMA5(Synonym)
Smpd5{ECO:0000312\|MGI:MGI:3709877}(Symbol)
Show All

PANTHER Classification

PANTHER Family:	SPHINGOMYELINASE FAMILY MEMBER (PTHR16320)
PANTHER Subfamily:	SPHINGOMYELIN PHOSPHODIESTERASE 5 (PTHR16320:SF9)
PANTHER GO-slim Molecular Function:	phospholipase activity
PANTHER GO-slim Biological Process:	phospholipid metabolic process amide metabolic process sphingolipid metabolic process
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	sphingomyelin phosphodiesterase activity, metal ion binding, phospholipase activity
GO BP Complete:	sphingomyelin metabolic process, sphingomyelin catabolic process, ceramide biosynthetic process, ceramide metabolic process
GO CC Complete:	endoplasmic reticulum membrane, mitochondrial membrane, cytoplasm, mitochondrion, extracellular region, mitochondrial inner membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
RAT\|RGD=2323312\|UniProtKB=A0A8I5ZX31	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000015040.6\|UniProtKB=F1N6X9	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000005922.5\|UniProtKB=F1RSL3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000011998.3\|UniProtKB=A0A9L0RJK1	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000052060.1\|UniProtKB=A0A5F5Y3B9	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845007381.1\|UniProtKB=A0A8I3MWL4	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000024098.3\|UniProtKB=F6Y1V4	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000015137.3\|UniProtKB=F6WVX2	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010000436.1\|UniProtKB=A0A8V0X7P6	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000005338.3\|UniProtKB=H9GA33	Anolis carolinensis	LDO
XENLA\|Gene=smpd5l.S\|UniProtKB=A0A310UD75	Xenopus laevis	O
XENLA\|Gene=smpd5l.L\|UniProtKB=A0A1L8I395	Xenopus laevis	LDO
XENTR\|Gene=smpd5l\|UniProtKB=A0A8J1J2J0	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000007890.2\|UniProtKB=H2LUW6	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-061110-22\|UniProtKB=F1QG30	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000008553.1\|UniProtKB=W5MPU5	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000005018.3\|UniProtKB=F6TXK0	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118417396\|UniProtKB=A0A9J7MTT9	Branchiostoma floridae	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_322081\|UniProtKB=E9GUV3	Daphnia pulex	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_29438\|UniProtKB=A9VB36	Monosiga brevicollis	LDO
EMENI\|EnsemblGenome=ANIA_00392\|UniProtKB=Q5BGD8	Emericella nidulans	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_22534\|UniProtKB=F4NV32	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_103250\|UniProtKB=B1N2Q2	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_061020\|UniProtKB=C4M9N5	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_178990\|UniProtKB=C4LUW2	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_067710\|UniProtKB=B1N4I9	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_125790\|UniProtKB=C4LVW5	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_022610\|UniProtKB=B1N2L7	Entamoeba histolytica	LDO
ENTH1\|EnsemblGenome=CL6EHI_007460\|UniProtKB=C4LYB8	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0272682\|UniProtKB=Q86IG2	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_148776\|UniProtKB=F0ZBZ3	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0288017\|UniProtKB=Q1ZXD9	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_159232\|UniProtKB=F1A3L7	Dictyostelium purpureum	LDO
TRIV3\|Gene_ORFName=TVAG_114450\|UniProtKB=A2FAR4	Trichomonas vaginalis	LDO
TRIV3\|Gene_ORFName=TVAG_486340\|UniProtKB=A2EEI1	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_180400\|UniProtKB=A2EE69	Trichomonas vaginalis	O
PARTE\|EnsemblGenome=GSPATT00018489001\|UniProtKB=A0DMK4	Paramecium tetraurelia	LDO
PHYRM\|Gene=H3H0V8_PHYRM\|UniProtKB=H3H0V8	Phytophthora ramorum	LDO
PHYRM\|Gene=H3H9A3_PHYRM\|UniProtKB=H3H9A3	Phytophthora ramorum	LDO
STAA8\|EnsemblGenome=SAOUHSC_02163\|UniProtKB=Q2FWP1	Staphylococcus aureus	O
BACCR\|EnsemblGenome=BC_0671\|UniProtKB=Q81HW0	Bacillus cereus	O
LEPIN\|EnsemblGenome=LA_1027\|UniProtKB=P59115	Leptospira interrogans	O
LEPIN\|EnsemblGenome=LA_3540\|UniProtKB=Q8CVE3	Leptospira interrogans	O
LEPIN\|EnsemblGenome=LA_4004\|UniProtKB=Q8CVD9	Leptospira interrogans	O
LEPIN\|EnsemblGenome=LA_1029\|UniProtKB=P59116	Leptospira interrogans	O