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Gene Symbol(s):
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Prex1
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| Organism: |
Mus musculus |
| View Gene in Tree |
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| Gene Name: |
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
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| Gene ID: |
MGI:3040696
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| Protein ID: |
Q69ZK0
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| Persistent Id: |
PTN000518871 |
| Alternate Ids: |
| PREX1_MOUSE(UniProtKB-ID) |
26355466(GI) |
| 277360(GeneID) |
Q8BN08(AltAccession) |
| MGI:3040696(MGI) |
PREX1(Synonym) |
| AK090301(EMBL) |
Prex1(Symbol) |
| ENSMUSG00000039621(Ensembl) |
BAD32446(EMBL-CDS) |
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Show All
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| GO MF Complete: |
protein serine/threonine kinase inhibitor activity, guanyl-nucleotide exchange factor activity, GTPase activator activity, phospholipid binding
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| GO BP Complete: |
T cell differentiation, regulation of actin filament polymerization, regulation of dendrite development, reactive oxygen species metabolic process, G protein-coupled receptor signaling pathway, neutrophil chemotaxis, positive regulation of cell adhesion, positive regulation of substrate adhesion-dependent cell spreading, negative regulation of TOR signaling, intracellular signal transduction, positive regulation of GTPase activity, positive regulation of cell migration
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| GO CC Complete: |
growth cone, perinuclear region of cytoplasm, dendritic shaft, cytosol, plasma membrane
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| Reactome Pathways: |
Signaling by Rho GTPases, G alpha (12/13) signalling events, Signal Transduction, RHOG GTPase cycle, Cell death signalling via NRAGE, NRIF and NADE, RHOJ GTPase cycle, GPCR downstream signalling, RHOA GTPase cycle, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, RHOQ GTPase cycle, RHO GTPase cycle, p75 NTR receptor-mediated signalling, NRAGE signals death through JNK, RAC2 GTPase cycle, Signaling by GPCR, RAC1 GTPase cycle, Death Receptor Signaling, RHOC GTPase cycle, RHOB GTPase cycle, CDC42 GTPase cycle, RAC3 GTPase cycle
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