PANTHER Gene Information   
Gene Symbol(s): Pde11a
Organism: Mus musculus
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Gene Name: Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
Gene ID: MGI:3036251
Protein ID: P0C1Q2
Persistent Id: PTN000142051
Alternate Ids:
A2AKR2(AltAccession) AL929133(EMBL)
MGI:3036251(MGI) CHEMBL4295711(ChEMBL)
PDE11(Synonym) PDE11_MOUSE(UniProtKB-ID)
ENSMUSG00000075270(Ensembl) 110815911(GI)
241489(GeneID) ENSMUSP00000097572(Ensembl_PRO)
NM_001081033(refSeq) ENSMUST00000099992(Ensembl_TRS)
3.1.4.35 {ECO:0000250|UniProtKB:Q9HCR9}(EC) Pde11a(Symbol)
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PANTHER Classification
PANTHER Family: CYCLIC NUCLEOTIDE PHOSPHODIESTERASE (PTHR11347)
PANTHER Subfamily: DUAL 3',5'-CYCLIC-AMP AND -GMP PHOSPHODIESTERASE 11A (PTHR11347:SF130)  
PANTHER GO-slim Molecular Function: cyclic-nucleotide phosphodiesterase activity
PANTHER GO-slim Biological Process: negative regulation of cAMP-mediated signaling
cAMP-mediated signaling
PANTHER GO-slim Cellular Component:
PANTHER protein class: phosphodiesterase
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity, 3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activity, metal ion binding, calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity, 3',5'-cyclic-GMP phosphodiesterase activity, cyclic-nucleotide phosphodiesterase activity, cGMP binding, 3',5'-cyclic-AMP phosphodiesterase activity
GO BP Complete: signal transduction, negative regulation of cGMP-mediated signaling, negative regulation of cAMP-mediated signaling, cAMP-mediated signaling
GO CC Complete: cytosol, perikaryon
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Nitric oxide stimulates guanylate cyclase, Signal Transduction, cGMP effects, Platelet homeostasis, G alpha (s) signalling events, Hemostasis, GPCR downstream signalling, Signaling by GPCR

Orthologs