PANTHER Gene Information

Gene Symbol(s):

Enpp4

Organism:

Mus musculus

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Gene Name:

Bis(5'-adenosyl)-triphosphatase enpp4

Gene ID:

MGI:2682634

Protein ID:

Q8BTJ4

Persistent Id:

PTN000016183

Alternate Ids:

MGI:2682634(MGI)	NPP-4(Synonym)
Q69ZX0(AltAccession)	ENPP4_MOUSE(UniProtKB-ID)
3.6.1.29(EC)	XM_006524134(refSeq)
ENSMUSG00000023961(Ensembl)	26354927(GI)
AK090098(EMBL)	BAD32326(EMBL-CDS)
224794(GeneID)	Enpp4(Symbol)
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PANTHER Classification

PANTHER Family:	ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE (PTHR10151)
PANTHER Subfamily:	BIS(5'-ADENOSYL)-TRIPHOSPHATASE ENPP4 (PTHR10151:SF79)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	hydrolase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	metal ion binding, bis(5'-adenosyl)-triphosphatase activity
GO BP Complete:	purine ribonucleoside catabolic process, positive regulation of blood coagulation, blood coagulation
GO CC Complete:	plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Immune System, Innate Immune System, Neutrophil degranulation

Orthologs

ID	Organism	Type
HUMAN\|HGNC=3359\|UniProtKB=Q9Y6X5	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000018231.6\|UniProtKB=H2QT42	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000007462.3\|UniProtKB=G3QWX9	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000042260.2\|UniProtKB=F7GTS7	Macaca mulatta	LDO
RAT\|RGD=1308689\|UniProtKB=D4A2W1	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000003499\|UniProtKB=A2VDP5	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000025788.4\|UniProtKB=F1RQS0	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000008799.4\|UniProtKB=F6RYF9	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000033409.3\|UniProtKB=A0A2I2U6N9	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845012734.1\|UniProtKB=A0A8I3NY55	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000018909.5\|UniProtKB=F7C782	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000008268.5\|UniProtKB=A0A6I8NMY4	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010008201.1\|UniProtKB=A0A8V0Y1B6	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000013087.3\|UniProtKB=G1KN79	Anolis carolinensis	LDO
XENLA\|Gene=enpp4\|UniProtKB=Q6AX80	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1013025\|UniProtKB=Q0VA77	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000004391.2\|UniProtKB=H2LHN8	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-050417-444\|UniProtKB=Q566N0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000015820.1\|UniProtKB=W5NFR6	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000013447.2\|UniProtKB=F6V2M0	Ciona intestinalis	O
BRAFL\|Gene=LOC118422636\|UniProtKB=A0A9J7LS27	Branchiostoma floridae	O
BRAFL\|Gene=LOC118422715\|UniProtKB=A0A9J7MYM4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118422873\|UniProtKB=A0A9J7MYX0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118412880\|UniProtKB=A0A9J7MLT8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118414765\|UniProtKB=A0A9J7MNR9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118422713\|UniProtKB=A0A9J7LQG8	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC593286\|UniProtKB=A0A7M7RHN6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC575587\|UniProtKB=A0A7M7PGD8	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00015283\|UniProtKB=Q17540	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00027847\|UniProtKB=A8WZR7	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00106243\|UniProtKB=A0A2A6BX18	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00281154\|UniProtKB=A0A2A6BHK3	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00106187\|UniProtKB=A0A2A6BX92	Pristionchus pacificus	O
ANOGA\|EnsemblGenome=AGAP000982\|UniProtKB=A7US29	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC004410\|UniProtKB=D7EJX0	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_31637\|UniProtKB=E9HBC0	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW020169\|UniProtKB=B7PZW0	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG121963\|UniProtKB=T1EGT4	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g106597\|UniProtKB=A7S6K6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g78986\|UniProtKB=A7RES2	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g106609\|UniProtKB=A7S6K7	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g122369\|UniProtKB=A7SL99	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g34059\|UniProtKB=A7RXG6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g203861\|UniProtKB=A7RY45	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g113741\|UniProtKB=A7SCY3	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g112601\|UniProtKB=A7SBU9	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g238441\|UniProtKB=A7RI34	Nematostella vectensis	O
YEAST\|SGD=S000000742\|UniProtKB=P39997	Saccharomyces cerevisiae	O
YEAST\|SGD=S000000621\|UniProtKB=P25353	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AEL050C\|UniProtKB=Q757R2	Eremothecium gossypii	O
CANAL\|CGD=CAL0000198423\|UniProtKB=A0A1D8PMG4	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_E09042g\|UniProtKB=Q6C6J4	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_07550\|UniProtKB=Q5AVY0	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_2G14770\|UniProtKB=Q4X044	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU00632\|UniProtKB=Q7SI20	Neurospora crassa	O
SCLS1\|Gene_ORFName=SS1G_11406\|UniProtKB=A7F1D6	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_04248\|UniProtKB=Q0UVG6	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPBC725.05c\|UniProtKB=O94323	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_00705\|UniProtKB=B6JWD1	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNC00130\|UniProtKB=Q5KLA9	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_02531\|UniProtKB=A0A0D1E3X0	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_10963\|UniProtKB=E3KMZ8	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_16076\|UniProtKB=E3L1R4	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_14025\|UniProtKB=F4PBN2	Batrachochytrium dendrobatidis	O
DICDI\|dictyBase=DDB_G0285897\|UniProtKB=Q54MJ8	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_39462\|UniProtKB=F0ZWD6	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_39457\|UniProtKB=F0ZWD7	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_57514\|UniProtKB=F0ZWD1	Dictyostelium purpureum	O
AMBTC\|EnsemblGenome=AMTR_s00136p00050090\|UniProtKB=W1NFJ5	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_103G00110\|UniProtKB=A0A0K9Q4V5	Zostera marina	O
MUSAM\|EnsemblGenome=Ma08_g05450\|UniProtKB=A0A804K376	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma10_g21130\|UniProtKB=A0A804KYM1	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_001304mg\|UniProtKB=K3XHD3	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3003G030700\|UniProtKB=C5XLV5	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb120900\|UniProtKB=B6SGJ5	Zea mays	O
ORYSJ\|EnsemblGenome=Os01g0196600\|UniProtKB=Q0JPW9	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_2g05970v3\|UniProtKB=A0A0Q3IBC7	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0236000\|UniProtKB=A0A8I6XQR5	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS3A02G103900\|UniProtKB=A0A3B6EFE3	Triticum aestivum	O
NELNU\|Gene_ORFName=HUJ06_018904\|UniProtKB=A0A1U7YSX6	Nelumbo nucifera	O
NELNU\|Gene_ORFName=HUJ06_002675\|UniProtKB=A0A1U8AJ13	Nelumbo nucifera	O
SPIOL\|Gene=Spnplp-1\|UniProtKB=Q9FS13	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr03g0087331\|UniProtKB=A0A251V540	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C700357370\|UniProtKB=A0A9R1V0T5	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C700357380\|UniProtKB=A0A9R1X0Z0	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C700357340\|UniProtKB=A0A9R1X4U3	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a023727mg\|UniProtKB=A0A022Q1Y8	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a005062mg\|UniProtKB=A0A022QLE2	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a024050mg\|UniProtKB=A0A022QH74	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a005162mg\|UniProtKB=A0A022QPJ9	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a025542mg\|UniProtKB=A0A022PVV1	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a022305mg\|UniProtKB=A0A022PXH3	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_19235\|UniProtKB=A0A1U8H9N9	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400030124\|UniProtKB=M1CYG5	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc07g037950.1\|UniProtKB=A0A3Q7HB47	Solanum lycopersicum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400030123\|UniProtKB=M1CYG2	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc07g037960.1\|UniProtKB=A0A3Q7I4S3	Solanum lycopersicum	O
TOBAC\|Gene=LOC107819662\|UniProtKB=A0A1S4CJ89	Nicotiana tabacum	O
TOBAC\|Gene=LOC107819665\|UniProtKB=A0A1S4CJ88	Nicotiana tabacum	O
TOBAC\|Gene=LOC107800902\|UniProtKB=A0A1S4AST4	Nicotiana tabacum	O
TOBAC\|Gene=LOC107800907\|UniProtKB=A0A1S4ASX1	Nicotiana tabacum	O
VITVI\|Gene_OrderedLocusName=VIT_11s0016g02300\|UniProtKB=F6HGW7	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_C03891\|UniProtKB=A0A059CVL3	Eucalyptus grandis	O
BRACM\|EnsemblGenome=Bra011129\|UniProtKB=M4D3S5	Brassica campestris	O
ARATH\|TAIR=locus=2134343\|UniProtKB=Q9SU82	Arabidopsis thaliana	O
BRANA\|Gene_ORFName=DARMORV10_A01P08440.1\|UniProtKB=A0A078HYE9	Brassica napus	O
BRACM\|EnsemblGenome=Bra011130\|UniProtKB=M4D3S6	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_A08P19570.1\|UniProtKB=A0A078FPE7	Brassica napus	O
BRACM\|EnsemblGenome=Bra010320\|UniProtKB=M4D1H0	Brassica campestris	O
ARATH\|TAIR=locus=2134363\|UniProtKB=Q9SU81	Arabidopsis thaliana	O
BRANA\|Gene_ORFName=GSBRNA2T00076800001\|UniProtKB=A0A078I0B8	Brassica napus	O
BRACM\|EnsemblGenome=Bra011128\|UniProtKB=M4D3S4	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00078768001\|UniProtKB=A0A078FMV2	Brassica napus	O
BRACM\|EnsemblGenome=Bra010321\|UniProtKB=M4D1H1	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00013755001\|UniProtKB=A0A078IYS4	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00044814001\|UniProtKB=A0A078GY87	Brassica napus	O
BRACM\|EnsemblGenome=Bra024138\|UniProtKB=M4E5T4	Brassica campestris	O
ARATH\|TAIR=locus=2134453\|UniProtKB=Q9SU83	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107901121\|UniProtKB=A0A1U8IWI7	Gossypium hirsutum	O
GOSHI\|Gene=LOC107887253\|UniProtKB=A0A1U8HLK2	Gossypium hirsutum	O
GOSHI\|Gene=LOC107937730\|UniProtKB=A0A1U8MKX7	Gossypium hirsutum	O
GOSHI\|Gene=LOC107907144\|UniProtKB=A0A1U8JHV0	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_037673\|UniProtKB=A0A061GKR3	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g042800mg\|UniProtKB=A0A067DV04	Citrus sinensis	O
CITSI\|Gene_ORFName=CISIN_1g046091mg\|UniProtKB=A0A067F3J0	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_006G150900v3\|UniProtKB=B9H8W6	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_018G066600v3\|UniProtKB=B9N5F9	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_03G033000\|UniProtKB=A0A2C9W468	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_16G102800\|UniProtKB=A0A2C9UBJ5	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_1855800\|UniProtKB=B9TIV7	Ricinus communis	O
RICCO\|Gene_ORFName=RCOM_1046730\|UniProtKB=B9RK58	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_01G002600\|UniProtKB=I1J4B5	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_07G129700\|UniProtKB=I1KJW0	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_08G028900\|UniProtKB=K7L4N7	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_05G222200\|UniProtKB=I1K642	Glycine max	O
MEDTR\|EnsemblGenome=MTR_6g092720\|UniProtKB=G7KJV4	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_8g101560\|UniProtKB=G7LJJ3	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr01_26800\|UniProtKB=A0A2I4GPP6	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_2G000490\|UniProtKB=A0A0A0LKN5	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_7G211200\|UniProtKB=M5VPF8	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_413874\|UniProtKB=D8RQW8	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c7_1990\|UniProtKB=A0A2K1K9Z1	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c11_25540\|UniProtKB=A0A2K1JW99	Physcomitrella patens	O
SELML\|EnsemblGenome=SELMODRAFT_442885\|UniProtKB=D8RWV5	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_128329\|UniProtKB=D8SYU0	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_99566\|UniProtKB=D8RQY2	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_442125\|UniProtKB=D8RQY1	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_99871\|UniProtKB=D8RQX9	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_110487\|UniProtKB=D8S717	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_103617\|UniProtKB=D8RWV6	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c8_13050\|UniProtKB=A0A7I3ZMR1	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0071s0108\|UniProtKB=A0A2R6WNS8	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0040s0009\|UniProtKB=A0A2R6X2I7	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_001860220\|UniProtKB=A0A1Y1I0D6	Klebsormidium nitens	O
SACS2\|EnsemblGenome=SSO0185\|UniProtKB=Q980U2	Sulfolobus solfataricus	O
SACS2\|EnsemblGenome=SSO2423\|UniProtKB=Q97W23	Sulfolobus solfataricus	O
HALSA\|EnsemblGenome=VNG_0264H\|UniProtKB=Q9HSF0	Halobacterium salinarum	O
THEKO\|EnsemblGenome=TK1071\|UniProtKB=Q5JE10	Thermococcus kodakaraensis	O
CHLAA\|EnsemblGenome=Caur_2668\|UniProtKB=A9WJH0	Chloroflexus aurantiacus	O
CHLAA\|EnsemblGenome=Caur_1343\|UniProtKB=A9W9T5	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO6579\|UniProtKB=O69954	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO3237\|UniProtKB=Q9Z4Z4	Streptomyces coelicolor	O
GLOVI\|Gene=Q7NK89_GLOVI\|UniProtKB=Q7NK89	Gloeobacter violaceus	O
GLOVI\|Gene=Q7NDL2_GLOVI\|UniProtKB=Q7NDL2	Gloeobacter violaceus	O
RHOBA\|EnsemblGenome=RB10690\|UniProtKB=Q7UKE3	Rhodopirellula baltica	O
BRADU\|Gene=Q89JH7_BRADU\|UniProtKB=Q89JH7	Bradyrhizobium diazoefficiens	O