PANTHER Gene Information

Gene Symbol(s):

Ccar2

Organism:

Mus musculus

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Gene Name:

Cell cycle and apoptosis regulator protein 2

Gene ID:

MGI:2444228

Protein ID:

Q8VDP4

Persistent Id:

PTN000370984

Alternate Ids:

Q8BWR5(AltAccession)	568987435(GI)
MGI:2444228(MGI)	CCAR2_MOUSE(UniProtKB-ID)
AAH25471(EMBL-CDS)	ENSMUSG00000033712(Ensembl)
ENSMUST00000035612(Ensembl_TRS)	BC021475(EMBL)
Cell division cycle and apoptosis regulator protein 2(Synonym)	Ccar2(Symbol)
219158(GeneID)	ENSMUSP00000036924(Ensembl_PRO)
NP_666167(refSeq)
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PANTHER Classification

PANTHER Family:	CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN (PTHR14304)
PANTHER Subfamily:	CELL CYCLE AND APOPTOSIS REGULATOR PROTEIN 2 (PTHR14304:SF12)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	regulation of DNA-templated transcription
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:	chromatin/chromatin-binding, or -regulatory protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	protein binding, enzyme inhibitor activity, RNA polymerase II complex binding, enzyme binding
GO BP Complete:	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage, RNA splicing, regulation of protein deacetylation, positive regulation of canonical Wnt signaling pathway, regulation of DNA-templated transcription, response to UV, mitochondrial fragmentation involved in apoptotic process, mRNA processing, DNA damage response, regulation of circadian rhythm, regulation of protein stability, negative regulation of catalytic activity, negative regulation of DNA-templated transcription, rhythmic process, negative regulation of cell growth, positive regulation of apoptotic process, regulation of DNA-templated transcription elongation, positive regulation of DNA damage checkpoint, Wnt signaling pathway, negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO CC Complete:	nucleus, DBIRD complex, cytoplasm, mitochondrial matrix, spindle, chromatin, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000020065.6\|UniProtKB=H2QVV3	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000002424.3\|UniProtKB=G3QJ10	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000021991.4\|UniProtKB=H9FXT0	Macaca mulatta	LDO
RAT\|RGD=1309922\|UniProtKB=F1LM55	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000005469.5\|UniProtKB=E1B9H3	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000009628.5\|UniProtKB=F1RMA3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000020651.4\|UniProtKB=F6VJ81	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000005666.6\|UniProtKB=M3W4H2	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845019929.1\|UniProtKB=A0A8I3P633	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000009328.4\|UniProtKB=F7FZS2	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000009829.3\|UniProtKB=A0A6I8NR65	Ornithorhynchus anatinus	LDO
ANOCA\|Ensembl=ENSACAG00000023505.3\|UniProtKB=H9GUP4	Anolis carolinensis	LDO
DANRE\|Gene=ccar2\|UniProtKB=A0A8N7UVX0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000015653.1\|UniProtKB=W5NF59	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118411384\|UniProtKB=A0A9J7KS61	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC575098\|UniProtKB=A0A7M7NF99	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00003085\|UniProtKB=A0A0S4XR43	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG18765\|UniProtKB=A8XU29	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00205029\|UniProtKB=A0A2A6CB81	Pristionchus pacificus	O
ANOGA\|EnsemblGenome=AGAP000463\|UniProtKB=A0A1S4G8W3	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC004563\|UniProtKB=D6WB55	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_237157\|UniProtKB=E9G368	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW023286\|UniProtKB=B7QIS5	Ixodes scapularis	O
DICDI\|dictyBase=DDB_G0274577\|UniProtKB=Q86A78	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_147099\|UniProtKB=F0Z7N3	Dictyostelium purpureum	O
TRIV3\|Gene_ORFName=TVAG_434140\|UniProtKB=A2DSJ7	Trichomonas vaginalis	O
CHLRE\|EnsemblGenome=CHLRE_06g283634v5\|UniProtKB=A0A2K3DPT9	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00010p00266660\|UniProtKB=W1NGD9	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_10G00160\|UniProtKB=A0A0K9Q391	Zostera marina	O
MUSAM\|EnsemblGenome=Ma11_g14520\|UniProtKB=A0A804L7V2	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_005696mg\|UniProtKB=K3XUT9	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3010G169600\|UniProtKB=A0A194YKS8	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb277410\|UniProtKB=A0A804PYC6	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb384230\|UniProtKB=A0A1D6P1C9	Zea mays	O
BRADI\|EnsemblGenome=BRADI_1g64680v3\|UniProtKB=A0A0Q3KC94	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.4HG0382930\|UniProtKB=M0ULD5	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS4B02G185800\|UniProtKB=A0A3B6ITZ6	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4A02G118700\|UniProtKB=A0A3B6HSR4	Triticum aestivum	O
BRADI\|EnsemblGenome=BRADI_1g37780v3\|UniProtKB=I1GXY1	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.7HG0717640\|UniProtKB=A0A8I6YGF9	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS7D02G364200\|UniProtKB=A0A3B6TMW1	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7B02G269000\|UniProtKB=A0A3B6SG35	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7A02G358500\|UniProtKB=A0A3B6RLY9	Triticum aestivum	O
NELNU\|Gene_ORFName=HUJ06_022753\|UniProtKB=A0A1U8B103	Nelumbo nucifera	O
SPIOL\|Gene=LOC110799782\|UniProtKB=A0A9R0J3V7	Spinacia oleracea	O
HELAN\|Gene_ORFName=HannXRQ_Chr08g0225211\|UniProtKB=A0A251U702	Helianthus annuus	O
HELAN\|Gene_ORFName=HanXRQr2_Chr08g0339491\|UniProtKB=A0A9K3IEH8	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C800402460\|UniProtKB=A0A9R1UPY2	Lactuca sativa	O
HELAN\|Gene_ORFName=HannXRQ_Chr17g0540651\|UniProtKB=A0A251RMG4	Helianthus annuus	O
HELAN\|Gene_ORFName=HanXRQr2_Chr17g0788751\|UniProtKB=A0A9K3DHN0	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr06g0255131\|UniProtKB=A0A251SE77	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C300114370\|UniProtKB=A0A9R1W7V5	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a000517mg\|UniProtKB=A0A022QNE9	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_14232\|UniProtKB=A0A2G2ZGU0	Capsicum annuum	O
SOLLC\|EnsemblGenome=Solyc04g008680.3\|UniProtKB=A0A3Q7FY73	Solanum lycopersicum	O
TOBAC\|Gene=LOC107807000\|UniProtKB=A0A1S4BCZ6	Nicotiana tabacum	O
TOBAC\|Gene=LOC107802770\|UniProtKB=A0A1S4AYR8	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi01g01040\|UniProtKB=F6HPP6	Vitis vinifera	O
BRANA\|Gene_ORFName=DARMORV10_C09P31000.1\|UniProtKB=A0A078FWR3	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_C02P51140.1\|UniProtKB=A0A078HH27	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A09P24110.1\|UniProtKB=A0A078JAC1	Brassica napus	O
BRACM\|EnsemblGenome=Bra017400\|UniProtKB=A0A3P5YFZ7	Brassica campestris	O
ARATH\|TAIR=locus=2056881\|UniProtKB=F4IS91	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107934907\|UniProtKB=A0A1U8M832	Gossypium hirsutum	O
GOSHI\|Gene=LOC107898725\|UniProtKB=A0A1U8INM6	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_011668\|UniProtKB=A0A061EB49	Theobroma cacao	O
POPTR\|EnsemblGenome=POPTR_010G166100v3\|UniProtKB=A0A2K1YV92	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_01G034200\|UniProtKB=A0A2C9WHF8	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_05G104800\|UniProtKB=A0A2C9VWH8	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0837540\|UniProtKB=B9S8Z8	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_01G051400\|UniProtKB=I1J5T5	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_02G109900\|UniProtKB=I1JE70	Glycine max	O
MEDTR\|EnsemblGenome=MTR_5g042000\|UniProtKB=G7JWF9	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr16_12140\|UniProtKB=A0A2I4HM08	Juglans regia	O
JUGRE\|Gene=LOC109013000\|UniProtKB=A0A6P9DX16	Juglans regia	O
JUGRE\|Gene=LOC108987687\|UniProtKB=A0A6P9DWH0	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_5G469040\|UniProtKB=A0A0A0KRX1	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_1G277900\|UniProtKB=A0A251R470	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_444593\|UniProtKB=D8SBC9	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_443360\|UniProtKB=D8S0P5	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c12_12730\|UniProtKB=A0A7I4F1A9	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c4_10880\|UniProtKB=A0A2K1KMY0	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0102s0024\|UniProtKB=A0A2R6WE75	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_001640140\|UniProtKB=A0A0U9HJZ3	Klebsormidium nitens	O