PANTHER Gene Information

Gene Symbol(s):

Amdhd2

Organism:

Mus musculus

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Gene Name:

N-acetylglucosamine-6-phosphate deacetylase

Gene ID:

MGI:2443978

Protein ID:

Q8JZV7

Persistent Id:

PTN000121950

Alternate Ids:

MGI:2443978(MGI)	74214170(GI)
BC037005(EMBL)	NAGA_MOUSE(UniProtKB-ID)
BAC36877(EMBL-CDS)	ENSMUST00000040735(Ensembl_TRS)
Amdhd2(Symbol)	ENSMUSG00000036820(Ensembl)
Q8BK10(AltAccession)	NAGA(Synonym)
245847(GeneID)	NM_172935(refSeq)
3.5.1.25 {ECO:0000250\|UniProtKB:Q9Y303}(EC)	ENSMUSP00000036141(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE (PTHR11113)
PANTHER Subfamily:	N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE (PTHR11113:SF14)
PANTHER GO-slim Molecular Function:	deacetylase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
PANTHER GO-slim Biological Process:	amino sugar catabolic process
PANTHER GO-slim Cellular Component:
PANTHER protein class:	deacetylase

Pathway Categories:

N-acetylglucosamine metabolism

N-acetylglucosamine-6-phosphate deacetylase

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	metal ion binding, N-acetylglucosamine-6-phosphate deacetylase activity
GO BP Complete:	N-acetylneuraminate catabolic process, N-acetylglucosamine catabolic process, N-acetylglucosamine metabolic process, negative regulation of UDP-N-acetylglucosamine biosynthetic process
GO CC Complete:	-

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Synthesis of substrates in N-glycan biosythesis, Asparagine N-linked glycosylation, Synthesis of UDP-N-acetyl-glucosamine, Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein, Metabolism of proteins, Post-translational protein modification

Orthologs

ID	Organism	Type
HUMAN\|HGNC=24262\|UniProtKB=Q9Y303	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000007654.6\|UniProtKB=H2R122	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000023912.2\|UniProtKB=G3RW11	Gorilla gorilla gorilla	LDO
RAT\|RGD=1304601\|UniProtKB=Q5BJY6	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000001022\|UniProtKB=A7MBC0	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000008057.5\|UniProtKB=A0A286ZZ76	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000012571.4\|UniProtKB=A0A9L0RTH9	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000001962.6\|UniProtKB=A0A5F5XR04	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845003862.1\|UniProtKB=A0A8I3RT68	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000015443.4\|UniProtKB=F6S4I5	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000013604.3\|UniProtKB=A0A6I8PCT3	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010017468.1\|UniProtKB=F1P5J8	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000001708.4\|UniProtKB=H9G5G2	Anolis carolinensis	LDO
XENLA\|Gene=amdhd2.L\|UniProtKB=A0A1L8EYA2	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-976354\|UniProtKB=B1H1C0	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000001282.2\|UniProtKB=H2L6W9	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-1871\|UniProtKB=Q6P0U0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000008993.1\|UniProtKB=W5MRE7	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000005785.3\|UniProtKB=F6RNB7	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118419446\|UniProtKB=A0A9J7LF71	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC577808\|UniProtKB=A0A7M7SWS1	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00010308\|UniProtKB=P34480	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00029055\|UniProtKB=A8X378	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00278244\|UniProtKB=A0A2A6BIL1	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0031099\|UniProtKB=Q9VR81	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP002347\|UniProtKB=Q7QBX3	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC032734\|UniProtKB=A0A139WIQ9	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_307072\|UniProtKB=E9G0Q8	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW018200\|UniProtKB=B7PE06	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG116040\|UniProtKB=T1EGC6	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g168601\|UniProtKB=A7SBC9	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG50168\|UniProtKB=B3RV02	Trichoplax adhaerens	LDO
CANAL\|CGD=CAL0000190825\|UniProtKB=A0A1D8PQG3	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_E20163g\|UniProtKB=Q6C586	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_01428\|UniProtKB=Q5BDF2	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_1G00450\|UniProtKB=Q4WL23	Neosartorya fumigata	O
ASPFU\|EnsemblGenome=AFUA_8G04100\|UniProtKB=Q4WCK5	Neosartorya fumigata	LDO
SCLS1\|Gene_ORFName=SS1G_14322\|UniProtKB=A7F9P1	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_07546\|UniProtKB=Q0UL18	Phaeosphaeria nodorum	O
NEUCR\|EnsemblGenome=NCU05828\|UniProtKB=Q7S5L5	Neurospora crassa	O
NEUCR\|EnsemblGenome=NCU04725\|UniProtKB=Q7S6H9	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_12836\|UniProtKB=A7F5F8	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_02546\|UniProtKB=Q0V0B8	Phaeosphaeria nodorum	LDO
CRYNJ\|EnsemblGenome=CNM01890\|UniProtKB=Q5K7M8	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_11364\|UniProtKB=A0A0D1CBF6	Ustilago maydis	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_37041\|UniProtKB=B8CBF9	Thalassiosira pseudonana	LDO
PHYPA\|EnsemblGenome=Pp3c14_13050\|UniProtKB=A0A2K1JHL2	Physcomitrella patens	LDO
SACS2\|EnsemblGenome=SSO2673\|UniProtKB=Q97VF3	Sulfolobus solfataricus	LDO
STRCO\|Gene_OrderedLocusName=SCO4284\|UniProtKB=Q9KXV7	Streptomyces coelicolor	LDO
MYCTU\|Gene_OrderedLocusName=Rv3332\|UniProtKB=O53382	Mycobacterium tuberculosis	LDO
CLOBH\|Gene_OrderedLocusName=CBO2834\|UniProtKB=A5I5S0	Clostridium botulinum	LDO
STRR6\|EnsemblGenome=spr1867\|UniProtKB=Q8DN83	Streptococcus pneumoniae	LDO
STAA8\|EnsemblGenome=SAOUHSC_00710\|UniProtKB=Q2G2U0	Staphylococcus aureus	LDO
LISMO\|Gene=Q8Y5F6_LISMO\|UniProtKB=Q8Y5F6	Listeria monocytogenes	O
LISMO\|Gene=Q8Y8E8_LISMO\|UniProtKB=Q8Y8E8	Listeria monocytogenes	LDO
BACSU\|EnsemblGenome=BSU_35010\|UniProtKB=O34450	Bacillus subtilis	LDO
BACCR\|EnsemblGenome=BC_4055\|UniProtKB=Q819D0	Bacillus cereus	LDO
THEMA\|EnsemblGenome=TM_0814\|UniProtKB=Q9WZS1	Thermotoga maritima	LDO
DEIRA\|EnsemblGenome=DR_A0066\|UniProtKB=Q9RZ88	Deinococcus radiodurans	LDO
GLOVI\|Gene=Q7NL19_GLOVI\|UniProtKB=Q7NL19	Gloeobacter violaceus	O
GLOVI\|Gene=Q7NM35_GLOVI\|UniProtKB=Q7NM35	Gloeobacter violaceus	LDO
BACTN\|EnsemblGenome=BT_0675\|UniProtKB=Q8A9Z0	Bacteroides thetaiotaomicron	LDO
BACTN\|EnsemblGenome=BT_0676\|UniProtKB=Q8A9Y9	Bacteroides thetaiotaomicron	O
BACTN\|EnsemblGenome=BT_3588\|UniProtKB=Q8A1S1	Bacteroides thetaiotaomicron	O
RHOBA\|EnsemblGenome=RB1356\|UniProtKB=Q7UXF7	Rhodopirellula baltica	O
RHOBA\|EnsemblGenome=RB12559\|UniProtKB=Q7UIF8	Rhodopirellula baltica	LDO
THEYD\|EnsemblGenome=THEYE_A0801\|UniProtKB=B5YK77	Thermodesulfovibrio yellowstonii	LDO
DICTD\|EnsemblGenome=Dtur_0223\|UniProtKB=B8E1M7	Dictyoglomus turgidum	LDO
FUSNN\|EnsemblGenome=FN1133\|UniProtKB=Q8REH0	Fusobacterium nucleatum	LDO
HAEIN\|EnsemblGenome=HI_0140\|UniProtKB=P44537	Haemophilus influenzae	LDO
SHEON\|Gene_OrderedLocusName=SO_3505\|UniProtKB=Q8EBK8	Shewanella oneidensis	LDO
VIBCH\|EnsemblGenome=VC_1783\|UniProtKB=Q9KR60	Vibrio cholerae	O
VIBCH\|EnsemblGenome=VC_0994\|UniProtKB=O32445	Vibrio cholerae	LDO
XANCP\|EnsemblGenome=XCC3372\|UniProtKB=Q8P5G9	Xanthomonas campestris	O
XANCP\|EnsemblGenome=XCC3410\|UniProtKB=Q8P5D1	Xanthomonas campestris	LDO
PSEAE\|EnsemblGenome=PA3758\|UniProtKB=Q9HXN7	Pseudomonas aeruginosa	LDO
SALTY\|EnsemblGenome=STM0683\|UniProtKB=Q8ZQX8	Salmonella typhimurium	LDO
YERPE\|Gene_OrderedLocusName=YPO0838\|UniProtKB=A0A5P8YDZ3	Yersinia pestis	O
YERPE\|Gene_OrderedLocusName=YPO2626\|UniProtKB=A0A380PKN3	Yersinia pestis	LDO
ECOLI\|EnsemblGenome=BAA35320\|UniProtKB=P0AF18	Escherichia coli	LDO