PANTHER Gene Information

Gene Symbol(s):

Pgap1

Organism:

Mus musculus

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Gene Name:

GPI inositol-deacylase

Gene ID:

MGI:2443342

Protein ID:

Q3UUQ7

Persistent Id:

PTN000398261

Alternate Ids:

3.1.-.-(EC)	Q8BQ77(AltAccession)
AC124538(EMBL)	254028203(GI)
BAC34614(EMBL-CDS)	241062(GeneID)
CHEMBL3259507(ChEMBL)	ENSMUSG00000073678(Ensembl)
Pgap1(Symbol)	Post-GPI attachment to proteins factor 1(Synonym)
PGAP1_MOUSE(UniProtKB-ID)	MGI:2443342(MGI)
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PANTHER Classification

PANTHER Family:	NEGATIVE REGULATOR OF VESICLE FORMATION-RELATED (PTHR15495)
PANTHER Subfamily:	GPI INOSITOL-DEACYLASE (PTHR15495:SF7)
PANTHER GO-slim Molecular Function:	carboxylic ester hydrolase activity
PANTHER GO-slim Biological Process:	GPI anchor metabolic process endoplasmic reticulum to Golgi vesicle-mediated transport
PANTHER GO-slim Cellular Component:	endoplasmic reticulum
PANTHER protein class:	transporter

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	phosphatidylinositol deacylase activity
GO BP Complete:	sensory perception of sound, GPI anchor biosynthetic process, anterior/posterior axis specification, head development, embryonic pattern specification, protein transport, positive regulation of ER to Golgi vesicle-mediated transport, forebrain regionalization
GO CC Complete:	endoplasmic reticulum membrane, endoplasmic reticulum

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Attachment of GPI anchor to uPAR, Post-translational modification: synthesis of GPI-anchored proteins, Metabolism of proteins, Post-translational protein modification

Orthologs

ID	Organism	Type
HUMAN\|HGNC=25712\|UniProtKB=Q75T13	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000012769.6\|UniProtKB=A0A2I3SWT9	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000001785.3\|UniProtKB=A0A2I2YM28	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000043369.2\|UniProtKB=H9EWD8	Macaca mulatta	LDO
RAT\|RGD=1303213\|UniProtKB=Q765A7	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000020416.5\|UniProtKB=E1BNQ0	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000016073.5\|UniProtKB=I3LKB2	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000019980.4\|UniProtKB=F7BTQ7	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000027828.4\|UniProtKB=A0A337SUT7	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845024751.1\|UniProtKB=A0A8I3PNL7	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000012214.4\|UniProtKB=F7CE20	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000038233.1\|UniProtKB=A0A6I8NWD3	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010010973.1\|UniProtKB=A0A8V0YFX7	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000013805.3\|UniProtKB=H9GKD5	Anolis carolinensis	LDO
XENLA\|Gene=pgap1\|UniProtKB=Q66J01	Xenopus laevis	LDO
XENTR\|Gene=pgap1\|UniProtKB=A0A8J1IV64	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000018243.3\|UniProtKB=H2MVK8	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-090313-216\|UniProtKB=A0A8M9PSV5	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000005267.1\|UniProtKB=W5MD90	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000000995.3\|UniProtKB=F6YLE1	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118419010\|UniProtKB=A0A9J7LE06	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC590142\|UniProtKB=A0A7M7NRN7	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00011835\|UniProtKB=Q22561	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG23146\|UniProtKB=A8Y4L4	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00304661\|UniProtKB=A0A8R1Z6F6	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0029789\|UniProtKB=Q9W495	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP011299\|UniProtKB=A0A1S4H698	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC005802\|UniProtKB=D6WW73	Tribolium castaneum	LDO
IXOSC\|EnsemblGenome=ISCW009887\|UniProtKB=B7PY84	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG194331\|UniProtKB=T1FVY1	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG189781\|UniProtKB=T1FRD4	helobdella robusta	LDO
TRIAD\|EnsemblGenome=TriadG53016\|UniProtKB=B3RN26	Trichoplax adhaerens	LDO
YEAST\|SGD=S000001869\|UniProtKB=P43571	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AFR521W\|UniProtKB=Q752Q2	Eremothecium gossypii	LDO
YARLI\|EnsemblGenome=YALI0_B10043g\|UniProtKB=Q6CF60	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_F30767g\|UniProtKB=Q6BZU7	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_F03927g\|UniProtKB=Q6C2Z2	Yarrowia lipolytica	LDO
EMENI\|Gene_ORFName=AN6702\|UniProtKB=Q5AYC8	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_7G05540\|UniProtKB=Q4WGM4	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU08021\|UniProtKB=Q7SAM0	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_07584\|UniProtKB=A7EQI2	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_05858\|UniProtKB=Q0UQV6	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC824.02\|UniProtKB=Q9UT41	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_01570\|UniProtKB=B6JYA9	Schizosaccharomyces japonicus	LDO
CRYNJ\|Gene_OrderedLocusName=CNF03000\|UniProtKB=P0CM50	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_04031\|UniProtKB=Q4P782	Ustilago maydis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_86108\|UniProtKB=F4NX85	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0280525\|UniProtKB=Q54VC2	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_37773\|UniProtKB=F0ZTD0	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_35_4350\|UniProtKB=E9AFR2	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb09.211.1830\|UniProtKB=Q38DX1	Trypanosoma brucei	LDO
TRYB2\|Gene_ORFName=Tb927.3.2610\|UniProtKB=Q582X3	Trypanosoma brucei	O
THAPS\|EnsemblGenome=THAPSDRAFT_4277\|UniProtKB=B8C1F0	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GL65_PHYRM\|UniProtKB=H3GL65	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_08g363950v5\|UniProtKB=A0A2K3DGP3	Chlamydomonas reinhardtii	LDO