PANTHER Gene Information

Gene Symbol(s):

Rin3

Organism:

Mus musculus

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Gene Name:

Ras and Rab interactor 3

Gene ID:

MGI:2385708

Protein ID:

P59729

Persistent Id:

PTN000559526

Alternate Ids:

238624151(GI)	BC137907(EMBL)
BAC27757(EMBL-CDS)	ENSMUSG00000044456(Ensembl)
MGI:2385708(MGI)	217835(GeneID)
B2RQF8(AltAccession)	RIN3_MOUSE(UniProtKB-ID)
RIN3(Synonym)	ENSMUSP00000060771(Ensembl_PRO)
ENSMUST00000056950(Ensembl_TRS)	Rin3(Symbol)
NP_808288(refSeq)
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PANTHER Classification

PANTHER Family:	RAB GDP/GTP EXCHANGE FACTOR (PTHR23101)
PANTHER Subfamily:	RAS AND RAB INTERACTOR 3 (PTHR23101:SF58)
PANTHER GO-slim Molecular Function:	small GTPase binding guanyl-nucleotide exchange factor activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	cytosol endocytic vesicle
PANTHER protein class:	guanyl-nucleotide exchange factor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	guanyl-nucleotide exchange factor activity, GTPase activator activity, small GTPase binding
GO BP Complete:	vesicle-mediated transport, negative regulation of receptor internalization, signal transduction, regulation of vesicle size, negative regulation of mast cell chemotaxis
GO CC Complete:	endocytic vesicle, dendrite, early endosome, cytoplasm, cytosol, cytoplasmic vesicle, vesicle, neuronal cell body, axon

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

RAB GEFs exchange GTP for GDP on RABs, Vesicle-mediated transport, Rab regulation of trafficking, Membrane Trafficking

Orthologs

ID	Organism	Type
HUMAN\|HGNC=18751\|UniProtKB=Q8TB24	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000006654.5\|UniProtKB=A0A2I3TTU9	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000008161.3\|UniProtKB=G3SDQ2	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000029233.3\|UniProtKB=A0A5F7ZDD7	Macaca mulatta	LDO
RAT\|RGD=1305849\|UniProtKB=A0A0G2K0G9	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000010416.5\|UniProtKB=G5E5D0	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000002451.5\|UniProtKB=F1SD71	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000009714.4\|UniProtKB=F6R8J2	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000007888.6\|UniProtKB=M3WVP9	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845021966.1\|UniProtKB=A0A8I3S2T2	Canis lupus familiaris	LDO
ORNAN\|Ensembl=ENSOANG00000003825.3\|UniProtKB=F6T5Y0	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010015431.1\|UniProtKB=A0A8V0YYW2	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000009141.4\|UniProtKB=G1KIJ2	Anolis carolinensis	LDO
XENLA\|Gene=rin3.S\|UniProtKB=A0A1L8F0E3	Xenopus laevis	O
XENLA\|Gene=rin3.L\|UniProtKB=A0A1L8F9J3	Xenopus laevis	LDO
XENTR\|Gene=rin3\|UniProtKB=A0A8J0QIM5	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000017864.2\|UniProtKB=A0A3B3H6K6	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-8871\|UniProtKB=E7FC22	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000014116.1\|UniProtKB=W5N9T8	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000016946.2\|UniProtKB=F7AK80	Ciona intestinalis	O
BRAFL\|Gene=LOC118410452\|UniProtKB=A0A9J7KQ43	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC100892488\|UniProtKB=A0A7M7HM26	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00008183\|UniProtKB=G5ECF0	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG11618\|UniProtKB=A8XDM7	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00102128\|UniProtKB=A0A2A6CRP3	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0085443\|UniProtKB=Q8MQW8	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP002493\|UniProtKB=A0A1S4GFP9	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC007758\|UniProtKB=D2A1H2	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_41981\|UniProtKB=E9FWX9	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW014154\|UniProtKB=B7QI18	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG188031\|UniProtKB=T1FPK4	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g244134\|UniProtKB=A7SBH6	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG64219\|UniProtKB=B3S6M0	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_23795\|UniProtKB=A9UUV1	Monosiga brevicollis	O
DICDI\|dictyBase=DDB_G0280165\|UniProtKB=Q54VS5	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_152723\|UniProtKB=F0ZM44	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_36_4660\|UniProtKB=Q4Q0U8	Leishmania major	O
TRYB2\|Gene_ORFName=Tb10.6k15.0260\|UniProtKB=Q389X4	Trypanosoma brucei	O
TRIV3\|Gene_ORFName=TVAG_266350\|UniProtKB=A2DQI8	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_533950\|UniProtKB=A2G1P2	Trichomonas vaginalis	O
PLAF7\|EnsemblGenome=PF3D7_1411000.2\|UniProtKB=A0A144A1B7	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_1411000.1\|UniProtKB=Q8ILY5	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_0815800\|UniProtKB=Q8IAZ5	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00003069001\|UniProtKB=A0DYI4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00020726001\|UniProtKB=A0DVK6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00032925001\|UniProtKB=A0BX06	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00004755001\|UniProtKB=A0BIL6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00021959001\|UniProtKB=A0E0H4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00000344001\|UniProtKB=Q6BG44	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028630001\|UniProtKB=A0BGC8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00037110001\|UniProtKB=A0CC09	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00024254001\|UniProtKB=A0E8A9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00003664001\|UniProtKB=A0E682	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00026989001\|UniProtKB=A0EH74	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_11750\|UniProtKB=B8CFG0	Thalassiosira pseudonana	O
PHYRM\|Gene=H3GXL1_PHYRM\|UniProtKB=H3GXL1	Phytophthora ramorum	O
PHYRM\|Gene=H3GC16_PHYRM\|UniProtKB=H3GC16	Phytophthora ramorum	O
PHYRM\|Gene=H3GX20_PHYRM\|UniProtKB=H3GX20	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_12g547450v5\|UniProtKB=A0A2K3D6F4	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00099p00124940\|UniProtKB=W1NWQ7	Amborella trichopoda	O
MUSAM\|EnsemblGenome=Ma06_g19870\|UniProtKB=A0A804JI59	Musa acuminata subsp. malaccensis	O
SORBI\|EnsemblGenome=SORBI_3001G017800\|UniProtKB=A0A1B6QGX3	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb310080\|UniProtKB=A0A804QBL9	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb090720\|UniProtKB=A0A804MJF1	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb086740\|UniProtKB=A0A804MHY6	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb064020\|UniProtKB=B4FJ70	Zea mays	O
BRADI\|EnsemblGenome=BRADI_1g02117v3\|UniProtKB=I1GL07	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0532440\|UniProtKB=A0A8I6YNT6	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS5B02G530300\|UniProtKB=A0A3B6LWH1	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4A02G343800\|UniProtKB=A0A3B6I382	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5B02G530100\|UniProtKB=A0A3B6LXU2	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5D02G529100\|UniProtKB=A0A3B6N1Y9	Triticum aestivum	O
NELNU\|Gene=LOC104593941\|UniProtKB=A0A1U7ZH74	Nelumbo nucifera	O
VITVI\|Gene_OrderedLocusName=VIT_18s0089g01070\|UniProtKB=F6GVX5	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_F04096\|UniProtKB=A0A059BY07	Eucalyptus grandis	O
GOSHI\|Gene=LOC107909145\|UniProtKB=A0A1U8JP88	Gossypium hirsutum	O
GOSHI\|Gene=LOC107928349\|UniProtKB=A0A1U8LKA6	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_036030\|UniProtKB=A0A061FIN5	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g014956mg\|UniProtKB=A0A067EJH3	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_019G066200v3\|UniProtKB=A0A2K1WQN4	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_18G119900\|UniProtKB=A0A2C9U3J0	Manihot esculenta	O
SOYBN\|EnsemblGenome=GLYMA_04G116900\|UniProtKB=I1JVP8	Glycine max	O
MEDTR\|EnsemblGenome=MTR_3g009180\|UniProtKB=G7J0B1	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr01_01930\|UniProtKB=A0A2I4FR95	Juglans regia	O
PRUPE\|EnsemblGenome=PRUPE_8G002200\|UniProtKB=M5VVY2	Prunus persica	O
AMBTC\|EnsemblGenome=AMTR_s00156p00017490\|UniProtKB=W1PJV0	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_82G00920\|UniProtKB=A0A0K9NLY7	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_25G01380\|UniProtKB=A0A0K9PHP0	Zostera marina	O
MUSAM\|EnsemblGenome=Ma03_g22050\|UniProtKB=A0A804IEX7	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma08_g17640\|UniProtKB=A0A804K7S9	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_035389mg\|UniProtKB=K4A933	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3001G428800\|UniProtKB=A0A1Z5SAD3	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb398120\|UniProtKB=B4FT69	Zea mays	O
ORYSJ\|EnsemblGenome=Os03g0262900\|UniProtKB=Q10NQ3	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_1g67360v3\|UniProtKB=I1H776	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.4HG0390140\|UniProtKB=M0WB23	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS4A02G088300\|UniProtKB=A0A3B6HQ63	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4D02G216400\|UniProtKB=A0A3B6JM94	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4B02G215900\|UniProtKB=A0A3B6IUD4	Triticum aestivum	O
NELNU\|Gene=LOC104612065\|UniProtKB=A0A1U8B944	Nelumbo nucifera	O
SPIOL\|Gene=LOC110787135\|UniProtKB=A0A9R0IDP3	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr15g0721861\|UniProtKB=A0A251SCS4	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr14g0663471\|UniProtKB=A0A251SGP9	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C900484050\|UniProtKB=A0A9R1UEP0	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C200092560\|UniProtKB=A0A9R1WBR7	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a005391mg\|UniProtKB=A0A022Q6P7	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_22143\|UniProtKB=A0A1U8DTK0	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400027521\|UniProtKB=M1CMP4	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc01g096990.3\|UniProtKB=A0A3Q7F6P1	Solanum lycopersicum	O
TOBAC\|Gene=LOC107829347\|UniProtKB=A0A1S4DG31	Nicotiana tabacum	O
TOBAC\|Gene=LOC107831518\|UniProtKB=A0A1S4DNP2	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi18g00334\|UniProtKB=F6H0N3	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_F03739\|UniProtKB=A0A059BX81	Eucalyptus grandis	O
BRANA\|Gene_ORFName=DARMORV10_C09P68030.1\|UniProtKB=A0A078G840	Brassica napus	O
BRACM\|EnsemblGenome=Bra009378\|UniProtKB=M4CYT1	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_C05P45020.1\|UniProtKB=A0A078GGY1	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00004031001\|UniProtKB=A0A078IP05	Brassica napus	O
BRACM\|EnsemblGenome=Bra022450\|UniProtKB=M4E103	Brassica campestris	O
ARATH\|TAIR=locus=2184727\|UniProtKB=F4KCK0	Arabidopsis thaliana	O
ARATH\|TAIR=locus=2092211\|UniProtKB=Q9LT31	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107962476\|UniProtKB=A0A1U8PVH9	Gossypium hirsutum	O
GOSHI\|Gene=LOC107918191\|UniProtKB=A0A1U8KL80	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_035005\|UniProtKB=A0A061FGH2	Theobroma cacao	O
POPTR\|EnsemblGenome=POPTR_005G171500v3\|UniProtKB=B9H791	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_02G158500\|UniProtKB=A0A2C9WEB3	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_14G142500\|UniProtKB=A0A2C9ULT2	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_1033030\|UniProtKB=B9RJC2	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_04G254000\|UniProtKB=I1JZB1	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_06G108200\|UniProtKB=I1KA37	Glycine max	O
MEDTR\|EnsemblGenome=MTR_3g073360\|UniProtKB=G7J457	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr13_27050\|UniProtKB=A0A2I4H3G7	Juglans regia	O
JUGRE\|EnsemblGenome=Jr16_03130\|UniProtKB=A0A2I4H0E4	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_2G128630\|UniProtKB=A0A0A0LI50	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_1G506400\|UniProtKB=M5XPK0	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_81029\|UniProtKB=D8R0M8	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_130016\|UniProtKB=D8T1L6	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c23_18370\|UniProtKB=A0A2K1IJX4	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0003s0258\|UniProtKB=A0A2R6XTI5	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_005080130\|UniProtKB=A0A1Y1IEC5	Klebsormidium nitens	O