PANTHER Gene Information

Gene Symbol(s):

Helz2

Organism:

Mus musculus

View Gene in Tree


Tree	Reduced Tree

Gene Name:

Helicase with zinc finger domain 2

Gene ID:

MGI:2385169

Protein ID:

E9QAM5

Persistent Id:

PTN000094535

Alternate Ids:

HELZ2_MOUSE(UniProtKB-ID)	BAH20441(EMBL-CDS)
B9A0U1(AltAccession)	MGI:2385169(MGI)
HELZ2(Synonym)	XM_006500599(refSeq)
ENSMUST00000108831(Ensembl_TRS)	Helz2(Symbol)
3.6.4.-(EC)	AL845506(EMBL)
ENSMUSP00000104459(Ensembl_PRO)	222424984(GI)
229003(GeneID)	ENSMUSG00000027580(Ensembl)
Show All

PANTHER Classification

PANTHER Family:	DNA2/NAM7 HELICASE FAMILY (PTHR10887)
PANTHER Subfamily:	HELICASE WITH ZINC FINGER DOMAIN 2 (PTHR10887:SF516)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	regulatory ncRNA-mediated post-transcriptional gene silencing
PANTHER GO-slim Cellular Component:	cytosol P granule
PANTHER protein class:	RNA helicase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	ATP hydrolysis activity, DNA binding, ATP binding, exoribonuclease II activity, zinc ion binding, RNA binding, RNA helicase activity
GO BP Complete:	regulatory ncRNA-mediated post-transcriptional gene silencing, positive regulation of transcription by RNA polymerase II
GO CC Complete:	cytoplasm, P granule, cytosol, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Cellular responses to stimuli, Cellular response to chemical stress, Cytoprotection by HMOX1, Metabolism, Metabolism of lipids, Regulation of lipid metabolism by PPARalpha, Cellular responses to stress

Orthologs

ID	Organism	Type
HUMAN\|HGNC=30021\|UniProtKB=Q9BYK8	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000013743.6\|UniProtKB=H2QKT0	Pan troglodytes	LDO
MACMU\|Ensembl=ENSMMUG00000006070.4\|UniProtKB=F6W2L0	Macaca mulatta	LDO
PIG\|Ensembl=ENSSSCG00000003306.5\|UniProtKB=F1RMM8	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000013636.4\|UniProtKB=A0A9L0SWH3	Equus caballus	LDO
MONDO\|Ensembl=ENSMODG00000005419.4\|UniProtKB=F6YK83	Monodelphis domestica	O
ANOCA\|Ensembl=ENSACAG00000002357.4\|UniProtKB=G1KAK6	Anolis carolinensis	O
ORYLA\|Ensembl=ENSORLG00000023540.1\|UniProtKB=A0A3B3HKE8	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000002944.2\|UniProtKB=H2LCN9	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-061013-333\|UniProtKB=Q08BA5	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000015507.1\|UniProtKB=W5NEM5	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000011434.2\|UniProtKB=F7AD70	Ciona intestinalis	O
BRAFL\|Gene=LOC118415744\|UniProtKB=A0A9J7L5S6	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC590861\|UniProtKB=A0A7M7MXZ7	Strongylocentrotus purpuratus	O
DROME\|FlyBase=FBgn0034187\|UniProtKB=A1ZAP7	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0033889\|UniProtKB=A1Z9K0	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0041164\|UniProtKB=Q6J5K9	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP011893\|UniProtKB=A0A1S4H8X7	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP006939\|UniProtKB=Q7PTC1	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC000208\|UniProtKB=D6WC75	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC010546\|UniProtKB=D6WE13	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC008350\|UniProtKB=D2A188	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_203262\|UniProtKB=E9HIC1	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW019555\|UniProtKB=B7PRC0	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG86659\|UniProtKB=T1G6F0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG132162\|UniProtKB=T1EHX3	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g93294\|UniProtKB=A7RTX4	Nematostella vectensis	O
MONBE\|EnsemblGenome=MONBRDRAFT_12543\|UniProtKB=A9VCL0	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_38187\|UniProtKB=A9V667	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_33641\|UniProtKB=A9V6R3	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_25856\|UniProtKB=A9V0N9	Monosiga brevicollis	O
ENTH1\|EnsemblGenome=CL6EHI_035920\|UniProtKB=C4M7F8	Entamoeba histolytica	O
GIAIC\|EnsemblGenome=GL50803_102858\|UniProtKB=A8BG19	Giardia intestinalis	O
TRIV3\|Gene_ORFName=TVAG_349570\|UniProtKB=A2EMN4	Trichomonas vaginalis	O
THAPS\|EnsemblGenome=THAPSDRAFT_269997\|UniProtKB=B8LDQ3	Thalassiosira pseudonana	O
CHLRE\|EnsemblGenome=CHLRE_15g641650v5\|UniProtKB=A0A2K3CWW2	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_12g542450v5\|UniProtKB=A0A2K3D6S9	Chlamydomonas reinhardtii	O
MARPO\|EnsemblGenome=MARPO_0078s0007\|UniProtKB=A0A2R6WL95	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_001200100\|UniProtKB=A0A1Y1HVN9	Klebsormidium nitens	O
AMBTC\|EnsemblGenome=AMTR_s00002p00272090\|UniProtKB=W1P3P5	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_238G00040\|UniProtKB=A0A0K9PHT8	Zostera marina	O
MUSAM\|EnsemblGenome=Ma03_g26670\|UniProtKB=A0A804IGM0	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_034108mg\|UniProtKB=K4A5F4	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3001G497000\|UniProtKB=C5WWZ2	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb403310\|UniProtKB=C0P7X4	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb004540\|UniProtKB=A0A1D6JP79	Zea mays	O
ORYSJ\|EnsemblGenome=Os03g0160400\|UniProtKB=Q10RG1	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_1g74450v3\|UniProtKB=I1H9H7	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.4HG0401930\|UniProtKB=A0A8I6Y3J4	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS4D02G275100\|UniProtKB=A0A3B6JNY6	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4A02G029400\|UniProtKB=A0A3B6HQY7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4B02G276500\|UniProtKB=A0A3B6IUP8	Triticum aestivum	O
NELNU\|Gene=LOC104596579\|UniProtKB=A0A1U7ZPN4	Nelumbo nucifera	O
SPIOL\|Gene=LOC110786202\|UniProtKB=A0A9R0JTY6	Spinacia oleracea	O
HELAN\|Gene_ORFName=HanXRQr2_Chr07g0287571\|UniProtKB=A0A9K3IK10	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C900488830\|UniProtKB=A0A9R1UGW5	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a001055mg\|UniProtKB=A0A022RNC2	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_16699\|UniProtKB=A0A2G2Z9F8	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400016310\|UniProtKB=M1BCF3	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc06g054050.2\|UniProtKB=A0A3Q7GWL8	Solanum lycopersicum	O
SOLLC\|EnsemblGenome=Solyc06g054020.3\|UniProtKB=A0A3Q7GWM0	Solanum lycopersicum	O
TOBAC\|Gene=LOC107821118\|UniProtKB=A0A1S4CP53	Nicotiana tabacum	O
TOBAC\|Gene=LOC107787108\|UniProtKB=A0A1S3ZI53	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi05g00530\|UniProtKB=D7T712	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_H03436\|UniProtKB=A0A059B4W4	Eucalyptus grandis	O
BRANA\|Gene_ORFName=DARMORV10_C05P03810.1\|UniProtKB=A0A078FAS0	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00087093001\|UniProtKB=A0A078IDL4	Brassica napus	O
BRACM\|EnsemblGenome=Bra015427\|UniProtKB=M4DG04	Brassica campestris	O
ARATH\|TAIR=locus=2200996\|UniProtKB=Q8GYD9	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107928604\|UniProtKB=A0A1U8LLG9	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_020661\|UniProtKB=A0A061EL55	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g002849mg\|UniProtKB=A0A067GGP6	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_008G155400v3\|UniProtKB=A0A2K1ZHV9	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_03G175900\|UniProtKB=A0A2C9W8F8	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0911670\|UniProtKB=B9RTN2	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_01G235200\|UniProtKB=K7K5I1	Glycine max	O
MEDTR\|EnsemblGenome=MTR_5g006890\|UniProtKB=G7K3T1	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_2g049990\|UniProtKB=G7IQH3	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr07_24960\|UniProtKB=A0A2I4DYD6	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_7G232550\|UniProtKB=A0A0A0K8W3	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_1G017300\|UniProtKB=M5XRP7	Prunus persica	O
EUCGR\|EnsemblGenome=EUGRSUZ_H04399\|UniProtKB=A0A059B7M1	Eucalyptus grandis	O
GOSHI\|Gene=LOC107945958\|UniProtKB=A0A1U8N952	Gossypium hirsutum	O
GOSHI\|Gene=LOC107888690\|UniProtKB=A0A1U8HQP1	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_026431\|UniProtKB=A0A061F2C9	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g038509mg\|UniProtKB=A0A067D4L4	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_005G047500v3\|UniProtKB=A0A2K2ABP0	Populus trichocarpa	O
POPTR\|Gene_ORFName=POPTR_T122601\|UniProtKB=A0A3N7FBI0	Populus trichocarpa	O
RICCO\|Gene_ORFName=RCOM_1428900\|UniProtKB=B9REU6	Ricinus communis	O
SELML\|EnsemblGenome=SELMODRAFT_137449\|UniProtKB=D8TDP4	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_431760\|UniProtKB=D8TDP5	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_430895\|UniProtKB=D8TAV7	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_236589\|UniProtKB=D8TAV8	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c12_8920\|UniProtKB=A0A2K1JPZ9	Physcomitrella patens	O
KLENI\|Gene_ORFName=KFL_000770020\|UniProtKB=A0A1Y1HZM8	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_000060480\|UniProtKB=A0A0U9HPZ5	Klebsormidium nitens	O
HALSA\|EnsemblGenome=VNG_2167G\|UniProtKB=Q9HNB7	Halobacterium salinarum	O