PANTHER Gene Information   
Gene Symbol(s): Fgd4
Organism: Mus musculus
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Gene Name: FYVE, RhoGEF and PH domain-containing protein 4
Gene ID: MGI:2183747
Protein ID: Q91ZT5
Persistent Id: PTN000292852
Alternate Ids:
224014(GeneID) AF402613(EMBL)
Fgd4(Symbol) Actin filament-binding protein frabin(Synonym)
ENSMUSG00000022788(Ensembl) BAC28733(EMBL-CDS)
Q3UEB6(AltAccession) 120538335(GI)
MGI:2183747(MGI) FGD4_MOUSE(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: FACIOGENITAL DYSPLASIA PROTEIN (PTHR12673)
PANTHER Subfamily: FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 4 (PTHR12673:SF98)  
PANTHER GO-slim Molecular Function: guanyl-nucleotide exchange factor activity
PANTHER GO-slim Biological Process: cytoskeleton organization
filopodium assembly
PANTHER GO-slim Cellular Component: cytoplasm
PANTHER protein class: guanyl-nucleotide exchange factor
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: actin filament binding, zinc ion binding, actin binding, guanyl-nucleotide exchange factor activity
GO BP Complete: regulation of cell shape, positive regulation of JUN kinase activity, cytoskeleton organization, positive regulation of JNK cascade, lamellipodium assembly, microspike assembly, filopodium assembly
GO CC Complete: cytoskeleton, cytoplasm, filopodium, lamellipodium
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Signaling by Rho GTPases, G alpha (12/13) signalling events, Signal Transduction, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, Cell death signalling via NRAGE, NRIF and NADE, p75 NTR receptor-mediated signalling, RHO GTPase cycle, NRAGE signals death through JNK, GPCR downstream signalling, Signaling by GPCR, Death Receptor Signaling, CDC42 GTPase cycle

Orthologs