PANTHER Gene Information

Gene Symbol(s):

Trpm8

Organism:

Mus musculus

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Gene Name:

Transient receptor potential cation channel subfamily M member 8

Gene ID:

MGI:2181435

Protein ID:

Q8R4D5

Persistent Id:

PTN000351214

Alternate Ids:

ENSMUST00000040210(Ensembl_TRS)	AC087780(EMBL)
Trp-p8(Synonym)	Trpm8(Symbol)
ENSMUSG00000036251(Ensembl)	EDL40112(EMBL-CDS)
CHEMBL3108632(ChEMBL)	449081289(GI)
171382(GeneID)	ENSMUSP00000131209(Ensembl_PRO)
E9Q165(AltAccession)	NM_134252(refSeq)
MGI:2181435(MGI)	TRPM8_MOUSE(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 (PTHR13800)
PANTHER Subfamily:	TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 8 (PTHR13800:SF9)
PANTHER GO-slim Molecular Function:	calcium channel activity ligand-gated monoatomic cation channel activity
PANTHER GO-slim Biological Process:	calcium ion transmembrane transport
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	ion channel

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	monoatomic ion channel activity, identical protein binding, protein binding, calcium channel activity, ligand-gated calcium channel activity
GO BP Complete:	response to cold, response to temperature stimulus, calcium ion transport, calcium ion transmembrane transport, thermoception, positive regulation of cold-induced thermogenesis, intracellular calcium ion homeostasis
GO CC Complete:	membrane, membrane raft, external side of plasma membrane, plasma membrane raft, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Transport of small molecules, Stimuli-sensing channels, Ion channel transport, TRP channels

Orthologs

ID	Organism	Type
HUMAN\|HGNC=17961\|UniProtKB=Q7Z2W7	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000052753.1\|UniProtKB=A0A2I3S1N6	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000013063.6\|UniProtKB=A0A2I3SDF4	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000008375.3\|UniProtKB=A0A2I2ZFH0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000046155.2\|UniProtKB=A0A1D5QLC8	Macaca mulatta	LDO
RAT\|RGD=620762\|UniProtKB=Q8R455	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000014652.5\|UniProtKB=E1BPC8	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000016314.6\|UniProtKB=F1SM15	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000011427.4\|UniProtKB=F7BEU9	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000009701.6\|UniProtKB=A0A5F5Y5X4	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845025630.1\|UniProtKB=A0A8I3PRR6	Canis lupus familiaris	LDO
ORNAN\|Ensembl=ENSOANG00000012747.5\|UniProtKB=A0A6I8P031	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010012680.1\|UniProtKB=A0A8V0YNB4	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000010093.3\|UniProtKB=A0A803TAX0	Anolis carolinensis	LDO
XENLA\|Gene=trpm8b.L\|UniProtKB=A0A1L8EWM8	Xenopus laevis	O
XENLA\|Gene=trpm8.L\|UniProtKB=C5IJY6	Xenopus laevis	LDO
XENTR\|Gene=trpm8\|UniProtKB=A0A8J1IVB0	Xenopus tropicalis	LDO
XENTR\|Xenbase=XB-GENE-998832\|UniProtKB=C5IJY7	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000016331.2\|UniProtKB=H2MNZ1	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-061214-4\|UniProtKB=A0A0R4IMY7	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000009806.1\|UniProtKB=W5MUC8	lepisosteus oculatus	O
BRAFL\|Gene=LOC118428674\|UniProtKB=A0A9J7N9U8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118432365\|UniProtKB=A0A9J7MGS6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118430808\|UniProtKB=A0A9J7MBB6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118407171\|UniProtKB=A0A9J7KAS3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118405175\|UniProtKB=A0A9J7HJB3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118432810\|UniProtKB=A0A9J7NBM0	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC754831\|UniProtKB=A0A7M7N0X8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC580138\|UniProtKB=A0A7M7HJW5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105443422\|UniProtKB=A0A7M7PF05	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115924300\|UniProtKB=A0A7M7SZA9	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC587471\|UniProtKB=A0A7M7PBT2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC584520\|UniProtKB=A0A7M7MY43	Strongylocentrotus purpuratus	O
HELRO\|EnsemblGenome=HelroG163554\|UniProtKB=T1EU74	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG190762\|UniProtKB=T1FS99	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g248535\|UniProtKB=A7T1N0	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG51314\|UniProtKB=B3RIG9	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG28218\|UniProtKB=B3S397	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG58797\|UniProtKB=B3S3P5	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG58796\|UniProtKB=B3S3P4	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG58798\|UniProtKB=B3S3P6	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG59044\|UniProtKB=B3S4D3	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG57357\|UniProtKB=B3RZ79	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG60588\|UniProtKB=B3S8M2	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_34057\|UniProtKB=A9V984	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_27446\|UniProtKB=A9V5A7	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_29245\|UniProtKB=A9VAJ3	Monosiga brevicollis	O