PANTHER Gene Information

Gene Symbol(s):

Arhgap44

Organism:

Mus musculus

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Gene Name:

Rho GTPase-activating protein 44

Gene ID:

MGI:2144423

Protein ID:

Q5SSM3

Persistent Id:

PTN000364791

Alternate Ids:

216831(GeneID)	BAC35316(EMBL-CDS)
MGI:2144423(MGI)	RhoGAP interacting with CIP4 homologs protein 2(Synonym)
Q5SSM7(AltAccession)	RHG44_MOUSE(UniProtKB-ID)
568973003(GI)	XP_006532935(refSeq)
Arhgap44{ECO:0000312\|MGI:MGI:2144423}(Symbol)	ENSMUSG00000033389(Ensembl)
AK053220(EMBL)
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PANTHER Classification

PANTHER Family:	3BP-1 RELATED RHOGAP (PTHR14130)
PANTHER Subfamily:	RHO GTPASE-ACTIVATING PROTEIN 44 (PTHR14130:SF13)
PANTHER GO-slim Molecular Function:	GTPase activator activity
PANTHER GO-slim Biological Process:	negative regulation of small GTPase mediated signal transduction endocytic recycling regulation of anatomical structure morphogenesis regulation of postsynapse organization neurotransmitter receptor transport to postsynaptic membrane regulation of actin cytoskeleton organization regulation of neuron projection development intracellular protein transport synapse organization protein localization to plasma membrane
PANTHER GO-slim Cellular Component:	presynaptic active zone postsynaptic density dendritic spine leading edge membrane intracellular anatomical structure
PANTHER protein class:	GTPase-activating protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	GTPase activator activity, small GTPase binding, phospholipid binding
GO BP Complete:	regulation of dendritic spine morphogenesis, regulation of actin cytoskeleton organization, signal transduction, negative regulation of Rac protein signal transduction, regulation of GTPase activity, modulation of chemical synaptic transmission, negative regulation of filopodium assembly, regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane, modification of postsynaptic structure
GO CC Complete:	postsynaptic density, dendrite, presynapse, postsynapse, presynaptic active zone, dendritic spine, leading edge membrane, recycling endosome, glutamatergic synapse, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Signaling by Rho GTPases, Signal Transduction, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, RHO GTPase cycle, RAC1 GTPase cycle, RHOA GTPase cycle, CDC42 GTPase cycle

Orthologs

ID	Organism	Type
HUMAN\|HGNC=29096\|UniProtKB=Q17R89	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000008787.6\|UniProtKB=A0A2I3SMH6	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000015831.3\|UniProtKB=A0A2I2ZFN0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000022515.4\|UniProtKB=F6YNY2	Macaca mulatta	LDO
RAT\|RGD=1305664\|UniProtKB=F1LQX4	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000021938.5\|UniProtKB=F1MFA5	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000018019.5\|UniProtKB=A0A5G2R4C3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000025167.4\|UniProtKB=A0A3Q2HA68	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000008402.6\|UniProtKB=A0A5F5XFK4	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845003750.1\|UniProtKB=A0A8I3MRN8	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000008107.4\|UniProtKB=A0A5F8HLE6	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000050303.1\|UniProtKB=A0A6I8PD85	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010029930.1\|UniProtKB=A0A3Q2TYW2	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000017636.3\|UniProtKB=A0A803TWX3	Anolis carolinensis	LDO
XENLA\|Gene=arhgap44.L\|UniProtKB=A0A8J1LSB7	Xenopus laevis	O
XENLA\|Gene=arhgap44.S\|UniProtKB=A0A8J1LYA3	Xenopus laevis	LDO
XENTR\|Gene=arhgap44\|UniProtKB=A0A8J1IXC5	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000012549.2\|UniProtKB=H2MAZ8	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000007345.2\|UniProtKB=A0A3B3IH89	Oryzias latipes	LDO
DANRE\|Gene=arhgap44\|UniProtKB=A0A8M9QN52	Danio rerio	O
DANRE\|Gene=si=ch211-114m9.1\|UniProtKB=A0A8M9Q151	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000013174.1\|UniProtKB=W5N6H5	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118428373\|UniProtKB=A0A9J7M5C5	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC592564\|UniProtKB=A0A7M7NQT0	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00021324\|UniProtKB=A0A2K5AU23	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00035078\|UniProtKB=A8XKD4	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00110064\|UniProtKB=A0A2A6D253	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0038747\|UniProtKB=Q9VDS5	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP009727\|UniProtKB=A0A1S4H2S3	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC003222\|UniProtKB=D6WE39	Tribolium castaneum	O
IXOSC\|EnsemblGenome=ISCW003282\|UniProtKB=B7PAK9	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG164475\|UniProtKB=T1EVH0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG190227\|UniProtKB=T1FRS7	helobdella robusta	O
MONBE\|EnsemblGenome=MONBRDRAFT_26508\|UniProtKB=A9V2K3	Monosiga brevicollis	O
USTMA\|EnsemblGenome=UMAG_01161\|UniProtKB=A0A0D1E6N8	Ustilago maydis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_25160\|UniProtKB=F4P2Y4	Batrachochytrium dendrobatidis	O
DICDI\|dictyBase=DDB_G0283955\|UniProtKB=Q54QB9	Dictyostelium discoideum	O