PANTHER Gene Information

Gene Symbol(s):

Upb1

Organism:

Mus musculus

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Gene Name:

Beta-ureidopropionase

Gene ID:

MGI:2143535

Protein ID:

Q8VC97

Persistent Id:

PTN000557657

Alternate Ids:

ENSMUST00000039925(Ensembl_TRS)	BC024447(EMBL)
N-carbamoyl-beta-alanine amidohydrolase(Synonym)	Upb1(Symbol)
19353933(GI)	ENSMUSG00000033427(Ensembl)
3.5.1.6(EC)	AAH24447(EMBL-CDS)
Q8R1K8(AltAccession)	NP_598756(refSeq)
MGI:2143535(MGI)	BUP1_MOUSE(UniProtKB-ID)
103149(GeneID)	ENSMUSP00000049342(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	NITRILASE C965.09-RELATED (PTHR43674)
PANTHER Subfamily:	BETA-UREIDOPROPIONASE (PTHR43674:SF2)
PANTHER GO-slim Molecular Function:	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	hydrolase

Pathway Categories:

Pyrimidine Metabolism

Beta-Ureidopropionase

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	zinc ion binding, protein homodimerization activity, beta-ureidopropionase activity
GO BP Complete:	dTMP catabolic process, protein homotetramerization, dUMP catabolic process, in utero embryonic development, beta-alanine metabolic process, beta-alanine biosynthetic process via 3-ureidopropionate, pyrimidine nucleoside catabolic process, liver development, protein homooligomerization, CMP catabolic process, dCMP catabolic process, UMP catabolic process
GO CC Complete:	cytosol

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Nucleotide catabolism, Pyrimidine catabolism, Metabolism of nucleotides, Metabolism

Orthologs

ID	Organism	Type
HUMAN\|HGNC=16297\|UniProtKB=Q9UBR1	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000014174.5\|UniProtKB=H2QLD8	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000002073.3\|UniProtKB=G3QI40	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000000262.4\|UniProtKB=F6X9A2	Macaca mulatta	LDO
RAT\|RGD=620091\|UniProtKB=Q03248	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000001325.5\|UniProtKB=A7MBE8	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000010060.5\|UniProtKB=A0A5G2R361	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000017804.4\|UniProtKB=F6SNP9	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000001510.6\|UniProtKB=M3VWS5	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845022513.1\|UniProtKB=A0A8I3S5R8	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000004002.4\|UniProtKB=A0A5F8H3Z3	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000015173.2\|UniProtKB=F6V4N0	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010026443.1\|UniProtKB=E1BU99	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000003242.4\|UniProtKB=H9G7A1	Anolis carolinensis	LDO
XENLA\|Gene=upb1.S\|UniProtKB=Q68F26	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-976127\|UniProtKB=B1H183	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000015770.2\|UniProtKB=H2MM12	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-1380\|UniProtKB=Q7T395	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000007024.1\|UniProtKB=W5MJG7	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000010868.3\|UniProtKB=F6WQG9	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118425999\|UniProtKB=A0A9J7N2Y2	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC585985\|UniProtKB=A0A7M7PC59	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00017440\|UniProtKB=Q19437	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG02618\|UniProtKB=A8WTW8	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00273798\|UniProtKB=A0A2A6B5N9	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0037513\|UniProtKB=Q9VI04	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP010229\|UniProtKB=Q7Q0P4	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC015857\|UniProtKB=D2A4C0	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_306977\|UniProtKB=E9H0A1	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW011368\|UniProtKB=B7Q5H6	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG110857\|UniProtKB=T1EF57	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g211696\|UniProtKB=A7SG03	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG26813\|UniProtKB=B3RYX4	Trichoplax adhaerens	LDO
DICDI\|dictyBase=DDB_G0274123\|UniProtKB=Q964D8	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_156598\|UniProtKB=F0ZWZ7	Dictyostelium purpureum	LDO
CHLRE\|EnsemblGenome=CHLRE_01g022650v5\|UniProtKB=A8HPY4	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00033p00236370\|UniProtKB=U5CWR7	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_33G00540\|UniProtKB=A0A0K9P7P9	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma05_g22240\|UniProtKB=A0A804J796	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma11_g20250\|UniProtKB=A0A804L9V2	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_029993mg\|UniProtKB=K3ZTR3	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3002G304000\|UniProtKB=C5X8L4	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb321550\|UniProtKB=B4FSZ8	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os07g0485100\|UniProtKB=Q8H530	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_1g27460v3\|UniProtKB=I1GUE5	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0493890\|UniProtKB=F2DDZ1	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS5D02G292000\|UniProtKB=A0A3B6MT04	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5B02G283800\|UniProtKB=A0A3B6LN86	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5A02G284600\|UniProtKB=A0A3B6KL37	Triticum aestivum	LDO
NELNU\|Gene=LOC104595495\|UniProtKB=A0A1U7ZZ71	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110801430\|UniProtKB=A0A9R0J773	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HanXRQr2_Chr04g0174131\|UniProtKB=A0A9K3J8K3	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr10g0444561\|UniProtKB=A0A251TKS2	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C500268200\|UniProtKB=A0A9R1VI88	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a007327mg\|UniProtKB=A0A022PRK4	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_25226\|UniProtKB=A0A1U8F8Y2	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400029019\|UniProtKB=M1CTZ5	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc10g047630.2\|UniProtKB=A0A3Q7IF15	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107801282\|UniProtKB=A0A1S4ATQ9	Nicotiana tabacum	O
TOBAC\|Gene=LOC107771508\|UniProtKB=A0A1S3Y2K8	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi03g01080\|UniProtKB=D7TU47	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_G00867\|UniProtKB=A0A059BAU5	Eucalyptus grandis	O
EUCGR\|EnsemblGenome=EUGRSUZ_G00862\|UniProtKB=A0A059BC33	Eucalyptus grandis	O
EUCGR\|EnsemblGenome=EUGRSUZ_G00868\|UniProtKB=A0A059BB30	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_A06P31050.1\|UniProtKB=A0A078J5Y0	Brassica napus	O
BRACM\|EnsemblGenome=Bra024290\|UniProtKB=M4E686	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_A09P08650.1\|UniProtKB=A0A078G238	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra037776\|UniProtKB=M4F9L3	Brassica campestris	LDO
ARATH\|TAIR=locus=2173348\|UniProtKB=Q8H183	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107947379\|UniProtKB=A0A1U8NEU9	Gossypium hirsutum	O
GOSHI\|Gene=LOC107928954\|UniProtKB=A0A1U8LMH0	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_007373\|UniProtKB=A0A061E2Y9	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g041243mg\|UniProtKB=A0A067ESV0	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_007G115900v3\|UniProtKB=B9HEB2	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_07G041800\|UniProtKB=A0A2C9VK01	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0449350\|UniProtKB=B9T3E5	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_07G182100\|UniProtKB=I1KL55	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_4g093580\|UniProtKB=G7JV38	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_4g093570\|UniProtKB=G7JV36	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr16_20700\|UniProtKB=A0A2I4F5F9	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_7G065130\|UniProtKB=A0A0A0K439	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_8G070200\|UniProtKB=M5VJY5	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_142105\|UniProtKB=D8QYN2	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_88684\|UniProtKB=D8R905	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c3_36650\|UniProtKB=A0A2K1KXJ9	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0006s0006\|UniProtKB=A0A2R6XPB7	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000760300\|UniProtKB=A0A1Y1HWE1	Klebsormidium nitens	LDO
KORCO\|EnsemblGenome=Kcr_0957\|UniProtKB=B1L5H4	Korarchaeum cryptofilum	LDO
SACS2\|EnsemblGenome=SSO2174\|UniProtKB=Q97WN8	Sulfolobus solfataricus	LDO
PYRAE\|EnsemblGenome=PAE3023\|UniProtKB=Q8ZTZ2	Pyrobaculum aerophilum	LDO
THEKO\|EnsemblGenome=TK0238\|UniProtKB=Q5JFS2	Thermococcus kodakaraensis	O
THEKO\|EnsemblGenome=TK1916\|UniProtKB=Q5JEU9	Thermococcus kodakaraensis	LDO
DEIRA\|EnsemblGenome=DR_2184\|UniProtKB=Q9RSE0	Deinococcus radiodurans	O
PSEAE\|EnsemblGenome=PA3093\|UniProtKB=Q9HZB5	Pseudomonas aeruginosa	O
CHLAA\|EnsemblGenome=Caur_3304\|UniProtKB=A9WJ33	Chloroflexus aurantiacus	LDO
CLOBH\|Gene_OrderedLocusName=CBO1821\|UniProtKB=A5I2U3	Clostridium botulinum	LDO
STRR6\|EnsemblGenome=spr0823\|UniProtKB=Q8DQ67	Streptococcus pneumoniae	LDO
DEIRA\|EnsemblGenome=DR_2535\|UniProtKB=Q9RRF7	Deinococcus radiodurans	LDO
GLOVI\|Gene=Q7NJZ9_GLOVI\|UniProtKB=Q7NJZ9	Gloeobacter violaceus	LDO
SYNY3\|Gene=P73046_SYNY3\|UniProtKB=P73046	Synechocystis	O
SYNY3\|EnsemblGenome=BAA10370\|UniProtKB=P55175	Synechocystis	LDO
BACTN\|EnsemblGenome=BT_0875\|UniProtKB=Q8A9E0	Bacteroides thetaiotaomicron	LDO
CHLTR\|EnsemblGenome=CT_534\|UniProtKB=O84539	Chlamydia trachomatis	LDO
RHOBA\|EnsemblGenome=RB1732\|UniProtKB=Q7UWX1	Rhodopirellula baltica	O
RHOBA\|EnsemblGenome=RB5695\|UniProtKB=Q7URF9	Rhodopirellula baltica	LDO
AQUAE\|EnsemblGenome=aq_103\|UniProtKB=O66508	Aquifex aeolicus	LDO
HELPY\|EnsemblGenome=HP_1238\|UniProtKB=O25836	Helicobacter pylori	O
BRADU\|EnsemblGenome=BAC51409\|UniProtKB=Q89H51	Bradyrhizobium diazoefficiens	O
HELPY\|EnsemblGenome=HP_1481\|UniProtKB=O26015	Helicobacter pylori	O
HELPY\|EnsemblGenome=HP_0757\|UniProtKB=O25452	Helicobacter pylori	LDO
GEOSL\|EnsemblGenome=GSU0651\|UniProtKB=Q74FF8	Geobacter sulfurreducens	O
GEOSL\|EnsemblGenome=GSU1027\|UniProtKB=Q74ED5	Geobacter sulfurreducens	LDO
XANCP\|EnsemblGenome=XCC2199\|UniProtKB=Q8P8P1	Xanthomonas campestris	LDO
PSEAE\|EnsemblGenome=PA2074\|UniProtKB=Q9I241	Pseudomonas aeruginosa	O
PSEAE\|EnsemblGenome=PA4802\|UniProtKB=Q9HV07	Pseudomonas aeruginosa	O
PSEAE\|EnsemblGenome=PA0293\|UniProtKB=Q9I6J8	Pseudomonas aeruginosa	LDO
YERPE\|Gene_OrderedLocusName=YPO0938\|UniProtKB=A0A2S9PFM0	Yersinia pestis	LDO