PANTHER Gene Information   
Gene Symbol(s): Terf2ip
Organism: Mus musculus
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Gene Name: Telomeric repeat-binding factor 2-interacting protein 1
Gene ID: MGI:1929871
Protein ID: Q91VL8
Persistent Id: PTN000420220
Alternate Ids:
ENSMUSP00000052170(Ensembl_PRO) 57321(GeneID)
Terf2ip(Symbol) Rap1(Synonym)
AK148508(EMBL) ENSMUST00000052138(Ensembl_TRS)
26349237(GI) BAC38258(EMBL-CDS)
MGI:1929871(MGI) ENSMUSG00000033430(Ensembl)
Q8C2Y1(AltAccession) TE2IP_MOUSE(UniProtKB-ID)
NP_065609(refSeq)
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PANTHER Classification
PANTHER Family: TELOMERE REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1 (PTHR16466)
PANTHER Subfamily: TELOMERIC REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1 (PTHR16466:SF6)  
PANTHER GO-slim Molecular Function: telomeric DNA binding
PANTHER GO-slim Biological Process: telomere capping
telomere maintenance via telomere lengthening
DNA damage response
PANTHER GO-slim Cellular Component: nuclear telomere cap complex
PANTHER protein class: homeodomain transcription factor
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: phosphatase binding, protein binding, telomeric DNA binding, G-rich strand telomeric DNA binding
GO BP Complete: positive regulation of canonical NF-kappaB signal transduction, positive regulation of non-canonical NF-kappaB signal transduction, telomere maintenance, regulation of DNA-templated transcription, negative regulation of DNA recombination at telomere, positive regulation of NF-kappaB transcription factor activity, negative regulation of protein phosphorylation, protection from non-homologous end joining at telomere, protein localization to chromosome, telomeric region, regulation of double-strand break repair via homologous recombination, telomere maintenance via telomere lengthening, telomere capping, negative regulation of telomere maintenance, positive regulation of telomere maintenance, intracellular signal transduction, regulation of telomere maintenance
GO CC Complete: chromosome, telomeric region, nucleus, nuclear body, cytoplasm, shelterin complex, nuclear telomere cap complex, male germ cell nucleus, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Cellular responses to stimuli, Inhibition of DNA recombination at telomere, Base-Excision Repair, AP Site Formation, DNA Repair, Base Excision Repair, Telomere Maintenance, Chromosome Maintenance, Extension of Telomeres, Telomere C-strand synthesis initiation, DNA Damage/Telomere Stress Induced Senescence, Cellular Senescence, Polymerase switching on the C-strand of the telomere, Recognition and association of DNA glycosylase with site containing an affected purine, Depurination, Processive synthesis on the C-strand of the telomere, Telomere Extension By Telomerase, Removal of the Flap Intermediate from the C-strand, Cleavage of the damaged purine, Cell Cycle, Cellular responses to stress, Telomere C-strand (Lagging Strand) Synthesis

Orthologs