PANTHER Gene Information

Gene Symbol(s):

Micu3

Organism:

Mus musculus

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Gene Name:

Calcium uptake protein 3, mitochondrial

Gene ID:

MGI:1925756

Protein ID:

Q9CTY5

Persistent Id:

PTN000265531

Alternate Ids:

MICU3(Synonym)	ENSMUSP00000070241(Ensembl_PRO)
NP_084386(refSeq)	ENSMUSG00000039478(Ensembl)
AK019353(EMBL)	78506(GeneID)
MICU3_MOUSE(UniProtKB-ID)	BAB31674(EMBL-CDS)
Micu3(Symbol)	81903900(GI)
ENSMUST00000068999(Ensembl_TRS)	MGI:1925756(MGI)
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PANTHER Classification

PANTHER Family:	EF HAND DOMAIN FAMILY A1,A2-RELATED (PTHR12294)
PANTHER Subfamily:	CALCIUM UPTAKE PROTEIN 3, MITOCHONDRIAL (PTHR12294:SF10)
PANTHER GO-slim Molecular Function:	calcium ion binding
PANTHER GO-slim Biological Process:	mitochondrial calcium ion homeostasis calcium ion transmembrane transport mitochondrial transmembrane transport
PANTHER GO-slim Cellular Component:	calcium channel complex inner mitochondrial membrane protein complex
PANTHER protein class:	calmodulin-related

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	protein heterodimerization activity, calcium ion binding, calcium ion sensor activity, calcium channel regulator activity
GO BP Complete:	calcium import into the mitochondrion, cellular response to calcium ion, positive regulation of neurotransmitter secretion, mitochondrial calcium ion homeostasis
GO CC Complete:	mitochondrial intermembrane space, uniplex complex, mitochondrion, mitochondrial inner membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Transport of small molecules, Processing of SMDT1, Mitochondrial calcium ion transport

Orthologs

ID	Organism	Type
HUMAN\|HGNC=27820\|UniProtKB=Q86XE3	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000020015.4\|UniProtKB=A0A2I3TPM8	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000004599.3\|UniProtKB=G3QPL1	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000017992.4\|UniProtKB=A0A5F8AIU4	Macaca mulatta	LDO
RAT\|RGD=1563411\|UniProtKB=A0A8I6A2H6	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000020468.6\|UniProtKB=F1MHU1	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000006981.5\|UniProtKB=F1SET8	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000012782.4\|UniProtKB=A0A5F5PKX1	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000018279.5\|UniProtKB=M3WNP3	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845014448.1\|UniProtKB=A0A8I3RY43	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000019058.4\|UniProtKB=A0A5F8GVT6	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000042609.1\|UniProtKB=A0A6I8P9Y7	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010016200.1\|UniProtKB=A0A1D5PEC4	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000006154.4\|UniProtKB=G1KF30	Anolis carolinensis	LDO
XENLA\|Gene=micu3.L\|UniProtKB=A0A8J0THP3	Xenopus laevis	LDO
XENTR\|Gene=micu3\|UniProtKB=A0A8J0QVT3	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000029285.1\|UniProtKB=H2M2E2	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000029556.1\|UniProtKB=A0A3B3I966	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-120813-5\|UniProtKB=E7FF65	Danio rerio	O
DANRE\|Gene=micu3a\|UniProtKB=A0A8M9Q0E9	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000013949.1\|UniProtKB=W5N991	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000004427.3\|UniProtKB=F6Y437	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118419842\|UniProtKB=A0A9J7LGE8	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC100889505\|UniProtKB=A0A7M7NGV1	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00008345\|UniProtKB=Q18874	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG06677\|UniProtKB=A8X2U3	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00118080\|UniProtKB=A0A2A6CH14	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0038735\|UniProtKB=A0A0B4KHF1	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP004179\|UniProtKB=Q7PQK6	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC009934\|UniProtKB=D6WQH5	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC001761\|UniProtKB=D6W8C9	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_323714\|UniProtKB=E9GZJ9	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG79826\|UniProtKB=T1G3T9	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g114933\|UniProtKB=A7SE58	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG56755\|UniProtKB=B3RWH9	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_32612\|UniProtKB=A9V0P9	Monosiga brevicollis	O
DICDI\|dictyBase=DDB_G0287825\|UniProtKB=Q54JS1	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_158565\|UniProtKB=F1A1X2	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_22_0920\|UniProtKB=Q4QBQ5	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.7.2960\|UniProtKB=Q57YA6	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_07_0110\|UniProtKB=Q4QIT3	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.8.1850\|UniProtKB=Q581Z7	Trypanosoma brucei	O
PHYRM\|Gene=H3GFW7_PHYRM\|UniProtKB=H3GFW7	Phytophthora ramorum	O
PHYRM\|Gene=H3GLG2_PHYRM\|UniProtKB=H3GLG2	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_12g499350v5\|UniProtKB=A8JGI1	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00033p00176330\|UniProtKB=U5CYR8	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_192G00120\|UniProtKB=A0A0K9PPE9	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_18G00440\|UniProtKB=A0A0K9PPF0	Zostera marina	O
MUSAM\|EnsemblGenome=Ma08_g24950\|UniProtKB=A0A804KAF8	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma06_g23150\|UniProtKB=A0A804JJF8	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_0097791mg\|UniProtKB=A0A0Q3QW48	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3006G138300\|UniProtKB=A0A1B6PLW0	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb426050\|UniProtKB=B8A1T8	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb078110\|UniProtKB=A0A804MDW2	Zea mays	O
ORYSJ\|EnsemblGenome=Os04g0502900\|UniProtKB=Q0JBY6	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_5g14860v3\|UniProtKB=I1IZD0	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0179570\|UniProtKB=A0A8I6XFB8	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS2A02G357500\|UniProtKB=A0A3B6B1B1	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2B02G376700\|UniProtKB=A0A3B6C982	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2D02G356300\|UniProtKB=A0A1D5UIR9	Triticum aestivum	O
SETIT\|EnsemblGenome=SETIT_017085mg\|UniProtKB=K3YS41	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3004G213300\|UniProtKB=C5XXL9	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb247020\|UniProtKB=A0A1D6HD01	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb184570\|UniProtKB=B6SL16	Zea mays	O
ORYSJ\|EnsemblGenome=Os02g0613000\|UniProtKB=Q0DZK7	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_3g48610v3\|UniProtKB=I1IBJ0	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0594010\|UniProtKB=A0A287U9C3	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS6A02G231100\|UniProtKB=A0A3B6NPN2	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6D02G204000\|UniProtKB=A0A3B6QHW7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6B02G250200\|UniProtKB=A0A3B6PNZ5	Triticum aestivum	O
NELNU\|Gene=LOC104592569\|UniProtKB=A0A1U7ZC81	Nelumbo nucifera	O
NELNU\|Gene=LOC104588584\|UniProtKB=A0A1U7YZ47	Nelumbo nucifera	O
SPIOL\|Gene=LOC110801133\|UniProtKB=A0A9R0J921	Spinacia oleracea	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a005202mg\|UniProtKB=A0A022PZB4	Erythranthe guttata	O
SOLLC\|EnsemblGenome=Solyc06g018050.3\|UniProtKB=A0A3Q7GPL6	Solanum lycopersicum	O
TOBAC\|Gene=LOC107768871\|UniProtKB=A0A1S3XU97	Nicotiana tabacum	O
TOBAC\|Gene=LOC107764571\|UniProtKB=A0A1S3XF75	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi04g00559\|UniProtKB=D7SV13	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_C02735\|UniProtKB=A0A059CSA9	Eucalyptus grandis	O
BRACM\|EnsemblGenome=Bra011319\|UniProtKB=M4D4B5	Brassica campestris	O
ARATH\|TAIR=locus=2116662\|UniProtKB=Q9SZ45	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107888403\|UniProtKB=A0A1U8HVL8	Gossypium hirsutum	O
GOSHI\|Gene=LOC107893455\|UniProtKB=A0A1U8I6X5	Gossypium hirsutum	O
GOSHI\|Gene=LOC107962910\|UniProtKB=A0A1U8PX66	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_036957\|UniProtKB=A0A061GJ18	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g010530mg\|UniProtKB=A0A067F6R9	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_018G023400v3\|UniProtKB=B9IL14	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_16G125200\|UniProtKB=A0A2C9UB22	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0922750\|UniProtKB=B9RP01	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_04G064800\|UniProtKB=K7KIG8	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_06G066000\|UniProtKB=K7KTG4	Glycine max	O
MEDTR\|EnsemblGenome=MTR_3g106550\|UniProtKB=G7JAF6	Medicago truncatula	O
SOYBN\|EnsemblGenome=GLYMA_17G213600\|UniProtKB=K7MN50	Glycine max	O
MEDTR\|EnsemblGenome=MTR_1g012850\|UniProtKB=A0A072VEI6	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr11_29790\|UniProtKB=A0A2I4ES53	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_4G652790\|UniProtKB=A0A0A0L4E8	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_1G485000\|UniProtKB=A0A251REU5	Prunus persica	O
HELAN\|EnsemblGenome=HanXRQr2_Chr16g0746121\|UniProtKB=A0A251S2X0	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C600341000\|UniProtKB=A0A9R1V616	Lactuca sativa	O
HELAN\|EnsemblGenome=HanXRQr2_Chr03g0091401\|UniProtKB=A0A251V4Z5	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C700360920\|UniProtKB=A0A9R1X150	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a005763mg\|UniProtKB=A0A022RE43	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_04475\|UniProtKB=A0A1U8FGW7	Capsicum annuum	O
SOLLC\|EnsemblGenome=Solyc02g014560.3\|UniProtKB=A0A3Q7EXD5	Solanum lycopersicum	O
TOBAC\|Gene=LOC107800726\|UniProtKB=A0A1S4AS99	Nicotiana tabacum	O
TOBAC\|Gene=LOC107766845\|UniProtKB=A0A1S3XN10	Nicotiana tabacum	O
TOBAC\|Gene=LOC107800003\|UniProtKB=A0A1S4APM3	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi11g00579\|UniProtKB=D7T4Y9	Vitis vinifera	O
GOSHI\|Gene=LOC107917577\|UniProtKB=A0A1U8KNV2	Gossypium hirsutum	O
GOSHI\|Gene=LOC107897923\|UniProtKB=A0A1U8ISX0	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_038216\|UniProtKB=A0A061GPD2	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g042758mg\|UniProtKB=A0A067EW02	Citrus sinensis	O
POPTR\|Gene_ORFName=POPTR_T109201\|UniProtKB=A0A3N7FH63	Populus trichocarpa	O
POPTR\|Gene_ORFName=POPTR_018G118001\|UniProtKB=A0A3N7HAD7	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_14G121300\|UniProtKB=A0A2C9UKM9	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_1371740\|UniProtKB=B9SZM7	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_17G107000\|UniProtKB=A0A0R0FB11	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_13G163900\|UniProtKB=K7M068	Glycine max	O
MEDTR\|EnsemblGenome=MTR_4g116190\|UniProtKB=G7JGM0	Medicago truncatula	O
CUCSA\|EnsemblGenome=Csa_2G009450\|UniProtKB=A0A0A0LJ54	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_7G257300\|UniProtKB=A0A251NH46	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_108925\|UniProtKB=D8S591	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_231573\|UniProtKB=D8RGN7	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c2_7480\|UniProtKB=A0A2K1L0L1	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c10_7560\|UniProtKB=A0A2K1JY40	Physcomitrella patens	O
KLENI\|Gene_ORFName=KFL_000540150\|UniProtKB=A0A0U9HJ85	Klebsormidium nitens	O