PANTHER Gene Information

Gene Symbol(s):

Sorbs2

Organism:

Mus musculus

View Gene in Tree


Tree	Reduced Tree

Gene Name:

Sorbin and SH3 domain-containing protein 2

Gene ID:

MGI:1924574

Protein ID:

Q3UTJ2

Persistent Id:

PTN000070035

Alternate Ids:

BAC33518(EMBL-CDS)	568954755(GI)
SRBS2_MOUSE(UniProtKB-ID)	Q3USC6(AltAccession)
ENSMUSG00000031626(Ensembl)	MGI:1924574(MGI)
AK122369(EMBL)	NP_001297636(refSeq)
234214(GeneID)	Arg/Abl-interacting protein 2(Synonym)
Sorbs2(Symbol)
Show All

PANTHER Classification

PANTHER Family:	SH3 DOMAIN-CONTAINING (PTHR14167)
PANTHER Subfamily:	SORBIN AND SH3 DOMAIN-CONTAINING PROTEIN 2 (PTHR14167:SF56)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	scaffold/adaptor protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	protein domain specific binding, identical protein binding, protein binding
GO BP Complete:	Notch signaling pathway, acetylcholine receptor signaling pathway, cell growth involved in cardiac muscle cell development, regulation of skeletal muscle acetylcholine-gated channel clustering
GO CC Complete:	Z disc, dendrite, cytoskeleton, perinuclear region of cytoplasm, focal adhesion, neuronal cell body, synapse, plasma membrane, apical plasma membrane, lamellipodium

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Immune System, Programmed Cell Death, Caspase-mediated cleavage of cytoskeletal proteins, Neuronal System, Innate Immune System, Neutrophil degranulation, Protein-protein interactions at synapses, Apoptosis, Neurexins and neuroligins, Apoptotic execution phase, Apoptotic cleavage of cellular proteins

Orthologs

ID	Organism	Type
HUMAN\|HGNC=24098\|UniProtKB=O94875	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000016657.6\|UniProtKB=H2QQJ1	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000013830.3\|UniProtKB=A0A2I2YV32	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000015733.4\|UniProtKB=F6S7N6	Macaca mulatta	LDO
RAT\|RGD=620061\|UniProtKB=O35413	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000016486.6\|UniProtKB=A0A3Q1MUK3	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000036679.3\|UniProtKB=A0A287A9Z6	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000007734.4\|UniProtKB=A0A3Q2H6X9	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000006911.6\|UniProtKB=A0A2I2V0K0	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845020043.1\|UniProtKB=A0A8I3P9G9	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000004845.4\|UniProtKB=A0A5F8H9P9	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000046049.1\|UniProtKB=A0A6I8NQY0	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010017094.1\|UniProtKB=A0A8V0Z6P7	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000001791.4\|UniProtKB=A0A803T1C9	Anolis carolinensis	LDO
XENLA\|Gene=LOC108706615\|UniProtKB=A0A8J1M152	Xenopus laevis	O
XENLA\|Gene=LOC108698663\|UniProtKB=A0A8J1MVB7	Xenopus laevis	LDO
XENTR\|Gene=sorbs2\|UniProtKB=A0A8J1J4M5	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000008216.3\|UniProtKB=H2LW34	Oryzias latipes	LDO
DANRE\|Gene=sorbs2b\|UniProtKB=A0A8M9PN75	Danio rerio	O
DANRE\|Gene=sorbs2a\|UniProtKB=A0A8M6YY36	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000013818.1\|UniProtKB=W5N8T4	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000000424.3\|UniProtKB=F7BKQ3	Ciona intestinalis	O
BRAFL\|Gene=LOC118412142\|UniProtKB=A0A9J7MKK3	Branchiostoma floridae	O
CAEEL\|WormBase=WBGene00007983\|UniProtKB=Q18501	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00026451\|UniProtKB=A8WVH1	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00012891\|UniProtKB=G5EC32	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG22368\|UniProtKB=A8Y232	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00113724\|UniProtKB=A0A2A6C3S5	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0010877\|UniProtKB=Q9VE96	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP001148\|UniProtKB=Q7PX05	Anopheles gambiae	O
DROME\|FlyBase=FBgn0033504\|UniProtKB=A0A6M3QH40	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP007717\|UniProtKB=A7UR66	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC031397\|UniProtKB=A0A139WAB9	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_197424\|UniProtKB=E9GLU7	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW008643\|UniProtKB=B7PZM2	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG167642\|UniProtKB=T1EZL7	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG167717\|UniProtKB=T1EZQ1	helobdella robusta	O
TRIAD\|EnsemblGenome=TriadG25635\|UniProtKB=B3RY92	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_10841\|UniProtKB=A9V7E3	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_34742\|UniProtKB=A9VDQ3	Monosiga brevicollis	O
CANAL\|CGD=CAL0000197718\|UniProtKB=Q5AGV0	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_F25443g\|UniProtKB=Q6C0E5	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_03819\|UniProtKB=Q5B6L1	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_2G03680\|UniProtKB=Q4WHZ3	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU03113\|UniProtKB=Q7SFY1	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_05310\|UniProtKB=A7EJ17	Sclerotinia sclerotiorum	O
SCLS1\|EnsemblGenome=SS1G_06016\|UniProtKB=A7EL19	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_00548\|UniProtKB=Q0V616	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPBC19C2.10\|UniProtKB=Q9UUD0	Schizosaccharomyces pombe	O
BATDJ\|Gene_ORFName=BATDEDRAFT_35211\|UniProtKB=F4P4A2	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_026470\|UniProtKB=C4M5W7	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=EHI_187770\|UniProtKB=C4M9I2	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_091530\|UniProtKB=C4M9E1	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_159850\|UniProtKB=C4LX60	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_105240\|UniProtKB=C4M128	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_010600\|UniProtKB=C4LYU7	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0291984\|UniProtKB=Q54DN5	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_86165\|UniProtKB=F0Z9Y7	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0291131\|UniProtKB=Q54F41	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_84454\|UniProtKB=F1A2P8	Dictyostelium purpureum	O