PANTHER Gene Information

Gene Symbol(s):

Alpi

Organism:

Mus musculus

View Gene in Tree


Tree	Reduced Tree

Gene Name:

Alkaline phosphatase

Gene ID:

MGI:1924018

Protein ID:

F8VPQ6

Persistent Id:

PTN000174573

Alternate Ids:

124487323(GI)	ENSMUST00000113270(Ensembl_TRS)
NP_001074551(refSeq)	ENSMUSP00000108895(Ensembl_PRO)
76768(GeneID)	MGI:1924018(MGI)
ENSMUSG00000079440(Ensembl)	F8VPQ6(Synonym)
F8VPQ6_MOUSE(UniProtKB-ID)
Show All

PANTHER Classification

PANTHER Family:	ALKALINE PHOSPHATASE (PTHR11596)
PANTHER Subfamily:	INTESTINAL-TYPE ALKALINE PHOSPHATASE (PTHR11596:SF30)
PANTHER GO-slim Molecular Function:	phosphatase activity
PANTHER GO-slim Biological Process:	dephosphorylation
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	phosphatase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	magnesium ion binding, zinc ion binding, protein homodimerization activity, phosphatase activity, protease binding, alkaline phosphatase activity
GO BP Complete:	cellular response to BMP stimulus, coenzyme A catabolic process
GO CC Complete:	extracellular space, external side of plasma membrane, plasma membrane, cell surface

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Post-translational modification: synthesis of GPI-anchored proteins, Metabolism of lipids, Membrane Trafficking, Intra-Golgi traffic, Vesicle-mediated transport, Intra-Golgi and retrograde Golgi-to-ER traffic, Digestion and absorption, Phospholipid metabolism, Metabolism, Synthesis of PA, Glycerophospholipid biosynthesis, Metabolism of proteins, Digestion, Post-translational protein modification

Orthologs

ID	Organism	Type
HUMAN\|HGNC=439\|UniProtKB=P05187	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000013034.6\|UniProtKB=H2QJL7	Pan troglodytes	O
HUMAN\|HGNC=441\|UniProtKB=P10696	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000013036.4\|UniProtKB=H2QJL9	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000038451.1\|UniProtKB=G3QVI4	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000016871.4\|UniProtKB=F7DQL5	Macaca mulatta	O
HUMAN\|HGNC=437\|UniProtKB=P09923	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000013035.4\|UniProtKB=H2QJL8	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000005653.3\|UniProtKB=G3RWG5	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000006985.4\|UniProtKB=F6T9Y1	Macaca mulatta	LDO
RAT\|RGD=2099\|UniProtKB=P15693	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000051665.1\|UniProtKB=A0A3Q1LIH7	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000053448.1\|UniProtKB=A0A3Q1MCB1	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000004519.6\|UniProtKB=F1N2M5	Bos taurus	O
BOVIN\|Gene=ALPI\|UniProtKB=P19111	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000012363.6\|UniProtKB=F1N6T5	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000039346.3\|UniProtKB=F1MPH8	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000016748.6\|UniProtKB=E1BJE3	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000016284.5\|UniProtKB=A0A287AF84	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000053339.1\|UniProtKB=A0A287A6H7	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000057909.1\|UniProtKB=A0A5G2QTH8	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000030540.3\|UniProtKB=A0A9L0TI55	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000015350.4\|UniProtKB=F6V551	Equus caballus	LDO
HORSE\|Ensembl=ENSECAG00000041300.2\|UniProtKB=A0A9L0TL44	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000026278.4\|UniProtKB=A0A337SRA7	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845025234.1\|UniProtKB=A0A8I3PK10	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000002592.3\|UniProtKB=F7G4Y2	Monodelphis domestica	LDO
CHICK\|Ensembl=ENSGALG00010017681.1\|UniProtKB=A0A8V0Z2E4	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000011629.3\|UniProtKB=A0A803TJP0	Anolis carolinensis	LDO
XENLA\|Gene=alpi.1.L\|UniProtKB=A1L2L6	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-854726\|UniProtKB=F7E932	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000006998.2\|UniProtKB=H2LRU1	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-050626-142\|UniProtKB=Q4QRJ9	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000004769.1\|UniProtKB=W5MBG9	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000025647.1\|UniProtKB=H2LRU2	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-050327-78\|UniProtKB=Q58EF1	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000004789.1\|UniProtKB=W5MBJ6	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000007082.3\|UniProtKB=F6W9Y0	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000006637.3\|UniProtKB=F6U0P5	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000021280.1\|UniProtKB=H2XPZ6	Ciona intestinalis	O
BRAFL\|Gene=LOC118430446\|UniProtKB=A0A9J7M9Q4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118420006\|UniProtKB=A0A9J7LHK8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118419277\|UniProtKB=A0A9J7LEX6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118430189\|UniProtKB=A0A9J7M8L5	Branchiostoma floridae	O
BRAFL\|Gene=LOC118410997\|UniProtKB=A0A9J7MIS3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118418799\|UniProtKB=A0A9J7MVT5	Branchiostoma floridae	O
BRAFL\|Gene=LOC118418802\|UniProtKB=A0A9J7LER5	Branchiostoma floridae	O
BRAFL\|Gene=LOC118418801\|UniProtKB=A0A9J7LD89	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC590138\|UniProtKB=A0A7M7NYW4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC589365\|UniProtKB=A0A7M7NZ72	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC578161\|UniProtKB=A0A7M7RFN6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC580300\|UniProtKB=A0A7M7SVQ6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC584498\|UniProtKB=A0A7M7SZG0	Strongylocentrotus purpuratus	O
PRIPA\|EnsemblGenome=WBGene00101800\|UniProtKB=A0A2A6CBC7	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00106338\|UniProtKB=A0A2A6BWW4	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0016123\|UniProtKB=Q24238	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP010596\|UniProtKB=Q7Q8R8	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC007539\|UniProtKB=D2A3C2	Tribolium castaneum	O
IXOSC\|EnsemblGenome=ISCW023785\|UniProtKB=B7QGN3	Ixodes scapularis	O
DROME\|FlyBase=FBgn0037786\|UniProtKB=Q9VH28	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0032779\|UniProtKB=Q9VIW9	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP011202\|UniProtKB=A0A1S4H720	Anopheles gambiae	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_194087\|UniProtKB=E9G5V0	Daphnia pulex	O
DROME\|FlyBase=FBgn0283479\|UniProtKB=M9PD70	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0043791\|UniProtKB=Q9VHD0	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP007300\|UniProtKB=Q7QJ58	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP004578\|UniProtKB=Q5TSZ8	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP012634\|UniProtKB=Q7PD92	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP001684\|UniProtKB=Q7PY02	Anopheles gambiae	O
DROME\|FlyBase=FBgn0038845\|UniProtKB=Q9VDG4	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0035620\|UniProtKB=Q9VRM9	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP011303\|UniProtKB=A0A1S4H697	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP028096\|UniProtKB=A0A1S4HCW1	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP011305\|UniProtKB=A7US49	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP006400\|UniProtKB=Q7PPB6	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP011302\|UniProtKB=A0A1S4H681	Anopheles gambiae	O
DROME\|FlyBase=FBgn0034712\|UniProtKB=Q9W273	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0035619\|UniProtKB=Q9VRM8	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0283480\|UniProtKB=Q9W274	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0034710\|UniProtKB=Q9W275	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0030661\|UniProtKB=Q9VXS8	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0033423\|UniProtKB=Q7K3X8	Drosophila melanogaster	O
TRICA\|EnsemblGenome=TC032020\|UniProtKB=A0A139WNY2	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC034155\|UniProtKB=A0A139WCZ9	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_319945\|UniProtKB=E9GNC2	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_269431\|UniProtKB=E9HZC0	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_228306\|UniProtKB=E9HCS7	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_328304\|UniProtKB=E9HCS6	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW000162\|UniProtKB=B7P0L3	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG185068\|UniProtKB=T1FMC8	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG67985\|UniProtKB=T1FZ90	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g162264\|UniProtKB=A7RSL3	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG54134\|UniProtKB=B3RR74	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG54135\|UniProtKB=B3RR75	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG22012\|UniProtKB=B3RR73	Trichoplax adhaerens	O
YEAST\|SGD=S000002889\|UniProtKB=P11491	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AGL260W\|UniProtKB=Q751G6	Eremothecium gossypii	O
CANAL\|CGD=CAL0000181464\|UniProtKB=A0A1D8PEV2	Candida albicans	O
CANAL\|CGD=CAL0000197686\|UniProtKB=Q5APN0	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_F16709g\|UniProtKB=Q6C1F6	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_10563\|UniProtKB=C8V8B5	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_2G03110\|UniProtKB=Q4WI47	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU08997\|UniProtKB=U9W3G5	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_03210\|UniProtKB=A7ED21	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_00453\|UniProtKB=Q0V6B1	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPBC14F5.13c\|UniProtKB=O60109	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_02853\|UniProtKB=B6K1C8	Schizosaccharomyces japonicus	O
USTMA\|EnsemblGenome=UMAG_10574\|UniProtKB=A0A0D1CPG7	Ustilago maydis	O
USTMA\|EnsemblGenome=UMAG_04114\|UniProtKB=A0A0D1C194	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_09482\|UniProtKB=E3KHJ4	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_15519\|UniProtKB=F4NRH6	Batrachochytrium dendrobatidis	O
DICDI\|dictyBase=DDB_G0278495\|UniProtKB=Q54Y02	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_42309\|UniProtKB=F1A1T9	Dictyostelium purpureum	O
THAPS\|EnsemblGenome=THAPSDRAFT_261067\|UniProtKB=B8BRL5	Thalassiosira pseudonana	O
PHYRM\|Gene=H3GMT2_PHYRM\|UniProtKB=H3GMT2	Phytophthora ramorum	O
METAC\|EnsemblGenome=MA_4354\|UniProtKB=Q8TI04	Methanosarcina acetivorans	O
HALSA\|EnsemblGenome=VNG_6301G\|UniProtKB=Q9HHP0	Halobacterium salinarum	O
CHLAA\|EnsemblGenome=Caur_2536\|UniProtKB=A9WI51	Chloroflexus aurantiacus	O
STAA8\|EnsemblGenome=SAOUHSC_02958\|UniProtKB=Q2FUY6	Staphylococcus aureus	O
BACSU\|EnsemblGenome=BSU_09410\|UniProtKB=P19406	Bacillus subtilis	O
BACSU\|EnsemblGenome=BSU_05740\|UniProtKB=P19405	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_4343\|UniProtKB=Q818C1	Bacillus cereus	O
THEMA\|EnsemblGenome=TM_0156\|UniProtKB=Q9WY03	Thermotoga maritima	O
GLOVI\|Gene=Q7NN47_GLOVI\|UniProtKB=Q7NN47	Gloeobacter violaceus	O
BACTN\|EnsemblGenome=BT_3708\|UniProtKB=Q8A1F8	Bacteroides thetaiotaomicron	O
RHOBA\|EnsemblGenome=RB5778\|UniProtKB=Q7URB0	Rhodopirellula baltica	O
THEYD\|EnsemblGenome=THEYE_A1782\|UniProtKB=B5YH83	Thermodesulfovibrio yellowstonii	O
DICTD\|EnsemblGenome=Dtur_0524\|UniProtKB=B8DZ84	Dictyoglomus turgidum	O
PSEAE\|EnsemblGenome=PA3296\|UniProtKB=P35483	Pseudomonas aeruginosa	O
YERPE\|Gene_OrderedLocusName=YPO2298\|UniProtKB=A0A5P8YG06	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAE76164\|UniProtKB=P00634	Escherichia coli	O