PANTHER Gene Information

Gene Symbol(s):

Usp13

Organism:

Mus musculus

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Gene Name:

Ubiquitin carboxyl-terminal hydrolase 13

Gene ID:

MGI:1919857

Protein ID:

Q5BKP2

Persistent Id:

PTN002363956

Alternate Ids:

3.4.19.12(EC)	ENSMUSG00000056900(Ensembl)
AC111140(EMBL)	60551238(GI)
Usp13(Symbol)	ENSMUST00000072312(Ensembl_TRS)
ENSMUSP00000072155(Ensembl_PRO)	UBP13(Synonym)
AAH90999(EMBL-CDS)	72607(GeneID)
D3YYG7(AltAccession)	NP_001013042(refSeq)
MGI:1919857(MGI)	UBP13_MOUSE(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE (PTHR24006)
PANTHER Subfamily:	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 13 (PTHR24006:SF682)
PANTHER GO-slim Molecular Function:	cysteine-type deubiquitinase activity
PANTHER GO-slim Biological Process:	protein deubiquitination
PANTHER GO-slim Cellular Component:	cytosol nucleus
PANTHER protein class:	cysteine protease

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	cysteine-type deubiquitinase activity, zinc ion binding, ubiquitin protein ligase binding, proteasome binding, ubiquitin binding, protein-folding chaperone binding, BAT3 complex binding, cysteine-type endopeptidase activity, K48-linked deubiquitinase activity, ubiquitin-like protein ligase binding
GO BP Complete:	cell population proliferation, regulation of protein stability, autophagy, proteolysis, regulation of autophagy, regulation of DNA-templated transcription, maintenance of unfolded protein, protein K6-linked deubiquitination, protein stabilization, positive regulation of ERAD pathway, protein K29-linked deubiquitination, protein K63-linked deubiquitination
GO CC Complete:	nucleus, cytoplasm, cytosol

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

PTEN Regulation, Regulation of PTEN stability and activity, Deubiquitination, Signal Transduction, Intracellular signaling by second messengers, Ub-specific processing proteases, PIP3 activates AKT signaling, Metabolism of proteins, Post-translational protein modification

Orthologs

ID	Organism	Type
HUMAN\|HGNC=12611\|UniProtKB=Q92995	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000015650.2\|UniProtKB=A0A2I3TG67	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000034809.2\|UniProtKB=A0A2I2Y8U6	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000003594.4\|UniProtKB=F7EMP5	Macaca mulatta	LDO
RAT\|RGD=1306044\|UniProtKB=D3ZDI9	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000005946\|UniProtKB=E1BMF7	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000011765.5\|UniProtKB=F1SGC5	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000004152.4\|UniProtKB=F7AWD8	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000025086.4\|UniProtKB=M3XC12	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845016860.1\|UniProtKB=A0A8I3NY77	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000021299.4\|UniProtKB=F7G3T7	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000050467.1\|UniProtKB=A0A6I8NWB7	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010018123\|UniProtKB=E1BY77	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000004318.4\|UniProtKB=G1KCT7	Anolis carolinensis	LDO
ORYLA\|Ensembl=ENSORLG00000005687.2\|UniProtKB=A0A3B3I0J6	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-080724-7\|UniProtKB=F1QFS9	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000001321.1\|UniProtKB=W5LZG4	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000006975.3\|UniProtKB=F6SBG8	Ciona intestinalis	O
CAEEL\|EnsemblGenome=WBGene00020839\|UniProtKB=A0A8D9I6U5	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG20283\|UniProtKB=A8XXG5	Caenorhabditis briggsae	O
DROME\|FlyBase=FBgn0035402\|UniProtKB=Q9VZU7	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP012248\|UniProtKB=Q7Q039	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC003401\|UniProtKB=D6WG65	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_215987\|UniProtKB=E9H6T7	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG105332\|UniProtKB=T1EDT8	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g78936\|UniProtKB=A7REZ3	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG50430\|UniProtKB=B3S034	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_27958\|UniProtKB=A9V6I6	Monosiga brevicollis	O
YEAST\|SGD=S000000262\|UniProtKB=P38237	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AGR023C\|UniProtKB=Q750D2	Eremothecium gossypii	O
YARLI\|EnsemblGenome=YALI0_B17072g\|UniProtKB=Q6CEB0	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_07422\|UniProtKB=Q5AWA8	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_2G06330\|UniProtKB=Q4WH81	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU05777\|UniProtKB=Q7S5R6	Neurospora crassa	O
SCLS1\|Gene_ORFName=SS1G_10528\|UniProtKB=A7EYW2	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_02884\|UniProtKB=Q0UZD0	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPBC6B1.06c\|UniProtKB=Q11119	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_00644\|UniProtKB=B6JW74	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNF02660\|UniProtKB=Q5KF83	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_00298\|UniProtKB=A0A0D1EBZ2	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_16962\|UniProtKB=E3L3H5	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_16102\|UniProtKB=F4NXU7	Batrachochytrium dendrobatidis	O
DICDI\|dictyBase=DDB_G0291239\|UniProtKB=P54201	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_57131\|UniProtKB=F0ZUI0	Dictyostelium purpureum	O
TRIV3\|Gene_ORFName=TVAG_204420\|UniProtKB=A2FJ36	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_219230\|UniProtKB=A2FKQ5	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_450920\|UniProtKB=A2EYP5	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_056730\|UniProtKB=A2ECN2	Trichomonas vaginalis	O
PHYRM\|Gene=H3GM71_PHYRM\|UniProtKB=H3GM71	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_02g080350v5\|UniProtKB=A0A2K3E0J5	Chlamydomonas reinhardtii	O