PANTHER Gene Information

Gene Symbol(s):

Coasy

Organism:

Mus musculus

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Gene Name:

Bifunctional coenzyme A synthase

Gene ID:

MGI:1918993

Protein ID:

Q9DBL7

Persistent Id:

PTN000075356

Alternate Ids:

AK004878(EMBL)	AAH20046(EMBL-CDS)
Q8K3Y4(AltAccession)	XP_017170260(refSeq)
85544617(GI)	ENSMUST00000107308(Ensembl_TRS)
CoA synthase(Synonym)	2.7.7.3 {ECO:0000269\|PubMed:11980892}(EC)
COASY_MOUSE(UniProtKB-ID)	MGI:1918993(MGI)
71743(GeneID)	Coasy{ECO:0000312\|MGI:MGI:1918993}(Symbol)
ENSMUSG00000001755(Ensembl)	ENSMUSP00000001806(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	DEPHOSPHO-COA KINASE-RELATED (PTHR10695)
PANTHER Subfamily:	BIFUNCTIONAL COENZYME A SYNTHASE-RELATED (PTHR10695:SF46)
PANTHER GO-slim Molecular Function:	kinase activity phosphotransferase activity, alcohol group as acceptor
PANTHER GO-slim Biological Process:	purine ribonucleotide biosynthetic process
PANTHER GO-slim Cellular Component:
PANTHER protein class:	kinase

Pathway Categories:

Coenzyme A biosynthesis

Pantetheine-phosphate adenyltransferase

Coenzyme A biosynthesis

Dephospho-CoA kinase

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ATP binding, dephospho-CoA kinase activity, pantetheine-phosphate adenylyltransferase activity
GO BP Complete:	coenzyme A biosynthetic process
GO CC Complete:	mitochondrial matrix, mitochondrial outer membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Metabolism of vitamins and cofactors, Metabolism, Coenzyme A biosynthesis, Vitamin B5 (pantothenate) metabolism, Metabolism of water-soluble vitamins and cofactors

Orthologs

ID	Organism	Type
HUMAN\|HGNC=29932\|UniProtKB=Q13057	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000009207.6\|UniProtKB=H2QD24	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000010858.3\|UniProtKB=G3R5K8	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000009886.4\|UniProtKB=F6YL76	Macaca mulatta	LDO
RAT\|RGD=1549767\|UniProtKB=Q5XIA5	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000046746.2\|UniProtKB=E1BEL9	Bos taurus	LDO
HORSE\|Ensembl=ENSECAG00000008468.4\|UniProtKB=F6VW73	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000033182.3\|UniProtKB=A0A2I2V4V8	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845008704.1\|UniProtKB=A0A8I3N964	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000043140.1\|UniProtKB=A0A5F8G850	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000042429.1\|UniProtKB=A0A6I8N321	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010021233.1\|UniProtKB=A0A8V0ZIN8	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000017967.4\|UniProtKB=A0A803SRM6	Anolis carolinensis	LDO
XENLA\|Gene=coasy.L\|UniProtKB=Q6DKD0	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-996485\|UniProtKB=F6U2L2	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000008430.2\|UniProtKB=A0A3B3H391	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040912-137\|UniProtKB=Q66HW0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000012461.1\|UniProtKB=W5N3Y4	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000001847.3\|UniProtKB=F6T7H6	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118424050\|UniProtKB=A0A9J7N0P0	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC115923837\|UniProtKB=A0A7M7SYR0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC579804\|UniProtKB=A0A7M7P7V6	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00022031\|UniProtKB=Q9BL56	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00040778\|UniProtKB=A8Y1N8	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG18542\|UniProtKB=A8XTJ2	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00273303\|UniProtKB=A0A2A6C727	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00097009\|UniProtKB=A0A8R1YC72	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00097027\|UniProtKB=A0A2A6BNP1	Pristionchus pacificus	LDO
ANOGA\|EnsemblGenome=AGAP005460\|UniProtKB=Q7Q774	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC005305\|UniProtKB=D6WVB0	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_52530\|UniProtKB=E9GMG2	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW001227\|UniProtKB=B7P746	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG82715\|UniProtKB=T1G4V7	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g246895\|UniProtKB=A7SR85	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG55032\|UniProtKB=B3RQL6	Trichoplax adhaerens	LDO
YEAST\|SGD=S000003509\|UniProtKB=P53332	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AGL356C\|UniProtKB=Q751P5	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000187822\|UniProtKB=A0A1D8PII4	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_D19426g\|UniProtKB=Q6C8I1	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_01694\|UniProtKB=Q5BCN6	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_4G08550\|UniProtKB=Q4WPA0	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU06029\|UniProtKB=Q7S4F6	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_04571\|UniProtKB=A7EGX9	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_00078\|UniProtKB=Q0V7D6	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC1F12.08\|UniProtKB=Q10350	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_05277\|UniProtKB=B6K169	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNB02350\|UniProtKB=Q5KMA7	Cryptococcus neoformans	LDO
PUCGT\|EnsemblGenome=PGTG_19438\|UniProtKB=E3L9H4	Puccinia graminis	LDO
PUCGT\|EnsemblGenome=PGTG_17702\|UniProtKB=E3L4H7	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_15838\|UniProtKB=E3L001	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_17522\|UniProtKB=F4P8R2	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_006770\|UniProtKB=C4M0F0	Entamoeba histolytica	LDO
ENTH1\|EnsemblGenome=CL6EHI_006680\|UniProtKB=B1N386	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0288465\|UniProtKB=Q54IX0	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_155029\|UniProtKB=F0ZSW3	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_32_2070\|UniProtKB=Q4Q569	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb11.01.6920\|UniProtKB=Q381Q8	Trypanosoma brucei	LDO
GIAIC\|EnsemblGenome=GL50803_7139\|UniProtKB=A8BTC2	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_463570\|UniProtKB=A2EH29	Trichomonas vaginalis	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_6416\|UniProtKB=B8C492	Thalassiosira pseudonana	LDO
CHLRE\|EnsemblGenome=CHLRE_13g590550v5\|UniProtKB=A0A2K3D148	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00045p00037700\|UniProtKB=W1P2W6	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_122G00560\|UniProtKB=A0A0K9Q0F7	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_5G02110\|UniProtKB=A0A0K9NU80	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma01_g05650\|UniProtKB=A0A804HQP0	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_031206mg\|UniProtKB=K3ZX74	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3002G052900\|UniProtKB=A0A1W0W2D1	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb301320\|UniProtKB=B6T8W5	Zea mays	O
ORYSJ\|EnsemblGenome=Os07g0179400\|UniProtKB=Q6ZLC4	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_1g55520v3\|UniProtKB=I1H341	Brachypodium distachyon	O
WHEAT\|EnsemblGenome=TraesCS6D02G219600\|UniProtKB=A0A3B6QIJ5	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6A02G237000\|UniProtKB=A0A3B6NPU8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6B02G265500\|UniProtKB=A0A3B6PPI4	Triticum aestivum	O
SETIT\|EnsemblGenome=SETIT_018301mg\|UniProtKB=K3YVK5	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3004G032200\|UniProtKB=C5XTW9	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb231510\|UniProtKB=A0A1D6GZS6	Zea mays	LDO
ORYSJ\|Gene_OrderedLocusName=LOC_Os02g04120\|UniProtKB=B9F2L1	Oryza sativa	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0554840\|UniProtKB=A0A8I6YQ96	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS6A02G098300\|UniProtKB=A0A3B6NM61	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6D02G084500\|UniProtKB=A0A3B6QDH3	Triticum aestivum	LDO
NELNU\|Gene=LOC104610970\|UniProtKB=A0A1U8B5C4	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110776852\|UniProtKB=A0A9R0HU60	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr09g0393651\|UniProtKB=A0A251TWL5	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C200078530\|UniProtKB=A0A9R1WC82	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a015030mg\|UniProtKB=A0A022RKC1	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_04181\|UniProtKB=A0A2G3A4C2	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_16149\|UniProtKB=A0A2G2Z7W4	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_34424\|UniProtKB=A0A2G2XWQ6	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400015508\|UniProtKB=M1B9A2	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc02g062640.3\|UniProtKB=A0A3Q7FJM3	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107808996\|UniProtKB=A0A1S4BJH5	Nicotiana tabacum	O
TOBAC\|Gene=LOC107785577\|UniProtKB=A0A1S3ZDB1	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi04g01320\|UniProtKB=D7SPB8	Vitis vinifera	O
VITVI\|EnsemblGenome=Vitvi18g02132\|UniProtKB=F6I458	Vitis vinifera	LDO
BRANA\|Gene_ORFName=GSBRNA2T00044992001\|UniProtKB=A0A078GYT8	Brassica napus	O
BRACM\|EnsemblGenome=Bra037227\|UniProtKB=M4F816	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_C07P04600.1\|UniProtKB=A0A078GFA0	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_C09P13900.1\|UniProtKB=A0A078JD42	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A07P02450.1\|UniProtKB=A0A078IAQ1	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra039623\|UniProtKB=M4FEV1	Brassica campestris	LDO
ARATH\|TAIR=locus=2062165\|UniProtKB=Q9ZPV8	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107889776\|UniProtKB=A0A1U8I2C0	Gossypium hirsutum	O
GOSHI\|Gene=LOC107890538\|UniProtKB=A0A1U8HWX3	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_000353\|UniProtKB=A0A061DH18	Theobroma cacao	O
GOSHI\|Gene=LOC107890899\|UniProtKB=A0A1U8HY93	Gossypium hirsutum	LDO
GOSHI\|Gene=LOC107933660\|UniProtKB=A0A1U8M7A3	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_012043\|UniProtKB=A0A061FU38	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g030486mg\|UniProtKB=A0A067FU79	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_005G121200v3\|UniProtKB=B9MXM7	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_02G095600\|UniProtKB=A0A2C9WCC9	Manihot esculenta	LDO
SOYBN\|EnsemblGenome=GLYMA_02G276900\|UniProtKB=C6THB5	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_5g020680\|UniProtKB=G7KEY2	Medicago truncatula	LDO
MEDTR\|EnsemblGenome=MTR_8g073890\|UniProtKB=G7L9G0	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr07_04480\|UniProtKB=A0A2I4ENM1	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_3G153200\|UniProtKB=A0A0A0L574	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_7G156900\|UniProtKB=M5W3M4	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_131418\|UniProtKB=D8T458	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_432221\|UniProtKB=D8TFC4	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c18_18790\|UniProtKB=A0A2K1J1K3	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c18_16890\|UniProtKB=A0A2K1J1E3	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0065s0018\|UniProtKB=A0A2R6WQR4	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_004520060\|UniProtKB=A0A1Y1IGS1	Klebsormidium nitens	LDO
KORCO\|EnsemblGenome=Kcr_1261\|UniProtKB=B1L6C8	Korarchaeum cryptofilum	LDO
PYRAE\|EnsemblGenome=PAE0887\|UniProtKB=Q8ZY96	Pyrobaculum aerophilum	LDO
METAC\|EnsemblGenome=MA_3546\|UniProtKB=Q8TK70	Methanosarcina acetivorans	LDO
METJA\|EnsemblGenome=MJ_1030\|UniProtKB=Q58436	Methanocaldococcus jannaschii	LDO
THEKO\|EnsemblGenome=TK2128\|UniProtKB=Q5JHE8	Thermococcus kodakaraensis	LDO
CHLAA\|EnsemblGenome=Caur_1902\|UniProtKB=A9WDV8	Chloroflexus aurantiacus	LDO
STRCO\|Gene_OrderedLocusName=SCO1996\|UniProtKB=Q9S2K7	Streptomyces coelicolor	LDO
MYCTU\|Gene_OrderedLocusName=Rv1631\|UniProtKB=P9WPA3	Mycobacterium tuberculosis	LDO
MYCGE\|EnsemblGenome=MG_264\|UniProtKB=P47506	mycoplasma genitalium	LDO
CLOBH\|Gene_OrderedLocusName=CBO3013\|UniProtKB=A5I692	Clostridium botulinum	LDO
STRR6\|EnsemblGenome=spr0873\|UniProtKB=Q8DQ32	Streptococcus pneumoniae	LDO
STAA8\|EnsemblGenome=SAOUHSC_01795\|UniProtKB=Q2FXP1	Staphylococcus aureus	LDO
LISMO\|EnsemblGenome=CAC99641\|UniProtKB=Q8Y6W8	Listeria monocytogenes	LDO
THEMA\|EnsemblGenome=TM_1387\|UniProtKB=Q9X1A7	Thermotoga maritima	LDO
DEIRA\|EnsemblGenome=DR_1892\|UniProtKB=Q9RT73	Deinococcus radiodurans	LDO
GLOVI\|EnsemblGenome=BAC90075\|UniProtKB=Q7NIP9	Gloeobacter violaceus	LDO
SYNY3\|EnsemblGenome=BAA10873\|UniProtKB=Q55515	Synechocystis	LDO
LEPIN\|EnsemblGenome=LA_3863\|UniProtKB=Q8EZJ0	Leptospira interrogans	LDO
BACTN\|EnsemblGenome=BT_4594\|UniProtKB=Q89YY6	Bacteroides thetaiotaomicron	LDO
CHLTR\|EnsemblGenome=CT_492\|UniProtKB=O84499	Chlamydia trachomatis	LDO
RHOBA\|EnsemblGenome=RB6607\|UniProtKB=Q7UQ02	Rhodopirellula baltica	LDO
AQUAE\|EnsemblGenome=aq_1985\|UniProtKB=O67792	Aquifex aeolicus	LDO
THEYD\|EnsemblGenome=THEYE_A0705\|UniProtKB=B5YJY2	Thermodesulfovibrio yellowstonii	LDO
DICTD\|EnsemblGenome=Dtur_0883\|UniProtKB=B8E081	Dictyoglomus turgidum	LDO
FUSNN\|EnsemblGenome=FN1932\|UniProtKB=Q8RHR7	Fusobacterium nucleatum	LDO
HELPY\|EnsemblGenome=HP_0831\|UniProtKB=O25502	Helicobacter pylori	LDO
NEIMB\|EnsemblGenome=NMB0331\|UniProtKB=Q4W580	Neisseria meningitidis serogroup b	LDO
GEOSL\|EnsemblGenome=GSU0513\|UniProtKB=Q74FU2	Geobacter sulfurreducens	LDO
BRADU\|EnsemblGenome=BAC45904\|UniProtKB=Q89WN9	Bradyrhizobium diazoefficiens	LDO
COXBU\|EnsemblGenome=CBU_0152\|UniProtKB=Q83F01	Coxiella burnetii	LDO
HAEIN\|EnsemblGenome=HI_0890\|UniProtKB=P44920	Haemophilus influenzae	LDO
SHEON\|Gene_OrderedLocusName=SO_0413\|UniProtKB=Q8EJP9	Shewanella oneidensis	LDO
VIBCH\|EnsemblGenome=VC_2427\|UniProtKB=Q9KPE3	Vibrio cholerae	LDO
XANCP\|EnsemblGenome=XCC3102\|UniProtKB=Q56764	Xanthomonas campestris	LDO
PSEAE\|EnsemblGenome=PA4529\|UniProtKB=Q9HVP8	Pseudomonas aeruginosa	LDO
SALTY\|EnsemblGenome=STM0140\|UniProtKB=P63828	Salmonella typhimurium	LDO
YERPE\|EnsemblGenome=YP_0254\|UniProtKB=Q8ZBI0	Yersinia pestis	LDO
ECOLI\|EnsemblGenome=BAE76040\|UniProtKB=P0A6I9	Escherichia coli	LDO