PANTHER Gene Information

Gene Symbol(s):

Kdsr

Organism:

Mus musculus

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Gene Name:

3-ketodihydrosphingosine reductase

Gene ID:

MGI:1918000

Protein ID:

Q6GV12

Persistent Id:

PTN000673050

Alternate Ids:

MGI:1918000(MGI)	1.1.1.102(EC)
NP_081810(refSeq)	KDSR_MOUSE(UniProtKB-ID)
ENSMUSG00000009905(Ensembl)	110625780(GI)
AY634684(EMBL)	AAT57900(EMBL-CDS)
Kdsr(Symbol)	ENSMUST00000010049(Ensembl_TRS)
70750(GeneID)	Fvt1(Synonym)
ENSMUSP00000010049(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	3-KETODIHYDROSPHINGOSINE REDUCTASE (PTHR43550)
PANTHER Subfamily:	3-KETODIHYDROSPHINGOSINE REDUCTASE (PTHR43550:SF3)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	reductase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	3-dehydrosphinganine reductase activity, NADPH binding
GO BP Complete:	3-keto-sphinganine metabolic process, sphingolipid biosynthetic process
GO CC Complete:	endoplasmic reticulum membrane, endoplasmic reticulum

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Sphingolipid metabolism, Sphingolipid de novo biosynthesis, Metabolism, Metabolism of lipids

Orthologs

ID	Organism	Type
HUMAN\|HGNC=4021\|UniProtKB=Q06136	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000010080.4\|UniProtKB=H2QEM9	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000013317.3\|UniProtKB=G3RBX4	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000006578.4\|UniProtKB=F7HPT5	Macaca mulatta	LDO
RAT\|RGD=1307775\|UniProtKB=A0A8I6AMK1	Rattus norvegicus	LDO
BOVIN\|Gene=KDSR\|UniProtKB=Q2KIJ5	Bos taurus	LDO
BOVIN\|Ensembl=ENSBTAG00000007723.5\|UniProtKB=F1MLE5	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000025744.4\|UniProtKB=F1SMW5	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000020472.4\|UniProtKB=A0A9L0S2B1	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000028024.4\|UniProtKB=A0A5F5XMX2	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845002496.1\|UniProtKB=A0A8I3MTG4	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000005258.4\|UniProtKB=F7GGW4	Monodelphis domestica	LDO
CHICK\|Ensembl=ENSGALG00010011817.1\|UniProtKB=A0A8V0YJG4	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000017590.4\|UniProtKB=H9GPF1	Anolis carolinensis	LDO
XENLA\|Gene=kdsr.L\|UniProtKB=A0A8J0VMQ0	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-985089\|UniProtKB=A0JM07	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000016803.2\|UniProtKB=H2MQK7	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-853\|UniProtKB=F1QWW8	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000012611.1\|UniProtKB=W5N4G9	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000003162.3\|UniProtKB=F6QEE3	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118418111\|UniProtKB=A0A9J7MV44	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC586074\|UniProtKB=A0A7M7N4R3	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00021367\|UniProtKB=U4PBL3	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG08294\|UniProtKB=A8X685	Caenorhabditis briggsae	LDO
DROME\|FlyBase=FBgn0039304\|UniProtKB=Q9VBU5	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP003984\|UniProtKB=Q7Q282	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC013591\|UniProtKB=D6W737	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_310703\|UniProtKB=E9FV83	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW009465\|UniProtKB=B7Q3N1	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW005309\|UniProtKB=B7PLM8	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG104089\|UniProtKB=T1EDJ6	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g213557\|UniProtKB=A7SK77	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG52550\|UniProtKB=B3RJ30	Trichoplax adhaerens	LDO
EMENI\|EnsemblGenome=ANIA_03249\|UniProtKB=Q5B881	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_08896\|UniProtKB=Q5AS34	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_8G02600\|UniProtKB=Q4WBK3	Neosartorya fumigata	O
SCLS1\|Gene_ORFName=SS1G_06864\|UniProtKB=A7ENG5	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_14287\|UniProtKB=Q0U1A7	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_07623\|UniProtKB=Q0UKU1	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_01230\|UniProtKB=Q0V434	Phaeosphaeria nodorum	O
USTMA\|EnsemblGenome=UMAG_05936\|UniProtKB=A0A0D1DQE2	Ustilago maydis	O
YARLI\|EnsemblGenome=YALI0_A19536g\|UniProtKB=Q6CGG6	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_B03190g\|UniProtKB=Q6CFW0	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_05850\|UniProtKB=Q5B0T0	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_2G08050\|UniProtKB=Q4X213	Neosartorya fumigata	O
SCLS1\|Gene_ORFName=SS1G_09883\|UniProtKB=A7EX24	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_02681\|UniProtKB=Q0UZY3	Phaeosphaeria nodorum	O
USTMA\|EnsemblGenome=UMAG_05069\|UniProtKB=A0A0D1E283	Ustilago maydis	O
USTMA\|EnsemblGenome=UMAG_03126\|UniProtKB=A0A0D1C4K5	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_18599\|UniProtKB=E3L7S5	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_18271\|UniProtKB=E3L7C1	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_87318\|UniProtKB=F4NY65	Batrachochytrium dendrobatidis	O
YEAST\|SGD=S000000469\|UniProtKB=P38342	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AEL164C\|UniProtKB=Q758B6	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000189000\|UniProtKB=Q59RQ2	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_B17688g\|UniProtKB=Q6CE86	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_01165\|UniProtKB=Q5BE65	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_1G11150\|UniProtKB=Q4WSZ0	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU00302\|UniProtKB=Q7RZR2	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_13203\|UniProtKB=A7F6H4	Sclerotinia sclerotiorum	LDO
SCLS1\|Gene_ORFName=SS1G_12770\|UniProtKB=A7F595	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_06762\|UniProtKB=Q0UNA2	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPCC1450.15\|UniProtKB=Q9Y7P2	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_02488\|UniProtKB=B6K2M1	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNG00270\|UniProtKB=P0CR36	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_10497\|UniProtKB=A0A0D1DX32	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_00181\|UniProtKB=E3JQE6	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_21723\|UniProtKB=F4NUX1	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_36291\|UniProtKB=F4PEJ6	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_200770\|UniProtKB=C4M3Y2	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0289057\|UniProtKB=Q54I23	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0289061\|UniProtKB=Q54I21	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_153204\|UniProtKB=F0ZNB1	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0272883\|UniProtKB=Q556J2	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_43831\|UniProtKB=F1A4W5	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_35_0330\|UniProtKB=E9AEL0	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb10.70.3240\|UniProtKB=Q38BJ6	Trypanosoma brucei	LDO
TRIV3\|Gene_ORFName=TVAG_468060\|UniProtKB=A2E0P5	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_0409500\|UniProtKB=C0H4A1	Plasmodium falciparum	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_3928\|UniProtKB=B8BWC8	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GM42_PHYRM\|UniProtKB=H3GM42	Phytophthora ramorum	O
PHYRM\|Gene=H3GGY9_PHYRM\|UniProtKB=H3GGY9	Phytophthora ramorum	O
PHYRM\|Gene=H3GMA7_PHYRM\|UniProtKB=H3GMA7	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_17g702750v5\|UniProtKB=A0A2K3CP34	Chlamydomonas reinhardtii	LDO
PHYPA\|EnsemblGenome=Pp3c22_10520\|UniProtKB=A0A2K1IN09	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0079s0060\|UniProtKB=A0A2R6WL16	Marchantia polymorpha	O
AMBTC\|EnsemblGenome=AMTR_s00025p00047220\|UniProtKB=W1PXX2	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_2G01050\|UniProtKB=A0A0K9PAI2	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_123G00630\|UniProtKB=A0A0K9Q2P9	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_67G00550\|UniProtKB=A0A0K9NU23	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma01_g01390\|UniProtKB=A0A804HP44	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma00_g01820\|UniProtKB=A0A804HME2	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma02_g06590\|UniProtKB=A0A804HZY2	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma11_g06140\|UniProtKB=A0A804L4S8	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma08_g15830\|UniProtKB=A0A804K726	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_017776mg\|UniProtKB=K3YU30	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3004G337066\|UniProtKB=A0A1Z5RQP3	Sorghum bicolor	O
SORBI\|EnsemblGenome=SORBI_3004G269700\|UniProtKB=C5Y0D5	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb188220\|UniProtKB=K7U3E5	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb251870\|UniProtKB=B4FEQ6	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os02g0701900\|UniProtKB=Q6ZHJ6	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g52570v3\|UniProtKB=I1ICY0	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0606930\|UniProtKB=A0A8I6Y3P3	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS6D02G245000\|UniProtKB=A0A3B6QJK4	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS6A02G270000\|UniProtKB=A0A3B6NT81	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6B02G297300\|UniProtKB=A0A3B6PQM5	Triticum aestivum	LDO
NELNU\|Gene=LOC104612425\|UniProtKB=A0A1U8BDX0	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110787450\|UniProtKB=A0A9R0JUN5	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr11g0516271\|UniProtKB=A0A251TFB9	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr10g0427291\|UniProtKB=A0A251THT9	Helianthus annuus	O
HELAN\|Gene_ORFName=HannXRQ_Chr11g0351371\|UniProtKB=A0A251TEI6	Helianthus annuus	O
HELAN\|Gene_ORFName=HanXRQr2_Chr01g0041501\|UniProtKB=A0A9K3JZ62	Helianthus annuus	O
HELAN\|Gene_ORFName=HannXRQ_Chr01g0028881\|UniProtKB=A0A251VTG0	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C400169600\|UniProtKB=A0A9R1VMG5	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C100020650\|UniProtKB=A0A9R1WLC7	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a009962mg\|UniProtKB=A0A022RM22	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a009921mg\|UniProtKB=A0A022RYM7	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_13334\|UniProtKB=A0A1U8GAS4	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG401011813\|UniProtKB=M1AUV1	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc06g054330.3\|UniProtKB=A0A3Q7GWR9	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107782703\|UniProtKB=A0A1S3Z3W7	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107785912\|UniProtKB=A0A1S3ZEB5	Nicotiana tabacum	O
TOBAC\|Gene=LOC107825367\|UniProtKB=A0A1S4D2Q6	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107790734\|UniProtKB=A0A1S3ZV33	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi05g01878\|UniProtKB=F6HDM3	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_B01115\|UniProtKB=A0A059D0J2	Eucalyptus grandis	O
EUCGR\|EnsemblGenome=EUGRSUZ_B01113\|UniProtKB=A0A059D1F0	Eucalyptus grandis	O
EUCGR\|EnsemblGenome=EUGRSUZ_B01114\|UniProtKB=A0A059D0X0	Eucalyptus grandis	LDO
BRANA\|EnsemblGenome=GSBRNA2T00072015001\|UniProtKB=A0A078JP15	Brassica napus	LDO
ARATH\|TAIR=locus=2182192\|UniProtKB=F4JZN6	Arabidopsis thaliana	LDO
BRANA\|Gene_ORFName=DARMORV10_A05P41940.1\|UniProtKB=A0A078GSY0	Brassica napus	O
BRACM\|EnsemblGenome=Bra020781\|UniProtKB=M4DW87	Brassica campestris	O
ARATH\|TAIR=locus=2080379\|UniProtKB=Q0WRJ2	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107899707\|UniProtKB=A0A1U8ISC8	Gossypium hirsutum	LDO
GOSHI\|Gene=LOC107957006\|UniProtKB=A0A1U8PC93	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_020543\|UniProtKB=A0A061ETE4	Theobroma cacao	O
THECC\|EnsemblGenome=TCM_020544\|UniProtKB=A0A061EKL2	Theobroma cacao	O
THECC\|EnsemblGenome=TCM_017113\|UniProtKB=A0A061ECT9	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g0177571mg\|UniProtKB=A0A067GH66	Citrus sinensis	LDO
CITSI\|Gene_ORFName=CISIN_1g030328mg\|UniProtKB=A0A067D151	Citrus sinensis	O
POPTR\|Gene_ORFName=POPTR_010G191800\|UniProtKB=A0A3N7FNN6	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_08G075500\|UniProtKB=A0A251KBP6	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0913540\|UniProtKB=B9RTW7	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_13G207200\|UniProtKB=I1M130	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_15G105400\|UniProtKB=K7MAQ6	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_3g098750\|UniProtKB=G7J3B1	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_2g022600\|UniProtKB=A0A072V634	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr12_12480\|UniProtKB=A0A2I4G9D0	Juglans regia	O
JUGRE\|EnsemblGenome=Jr07_20340\|UniProtKB=A0A6P9EVN2	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_3G149900\|UniProtKB=A0A0A0L506	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_6G171900\|UniProtKB=M5W7V2	Prunus persica	O
PRUPE\|EnsemblGenome=PRUPE_6G197600\|UniProtKB=A0A251NSY5	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_78109\|UniProtKB=D8QV40	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_79314\|UniProtKB=D8QU45	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c22_14290\|UniProtKB=A0A2K1ING5	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0005s0172\|UniProtKB=A0A2R6XR68	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000040370\|UniProtKB=A0A1Y1HMR4	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_000290410\|UniProtKB=A0A1Y1HQX6	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_004050110\|UniProtKB=A0A1Y1IHF7	Klebsormidium nitens	LDO
METAC\|EnsemblGenome=MA_2091\|UniProtKB=Q8TP33	Methanosarcina acetivorans	LDO