PANTHER Gene Information

Gene Symbol(s):

Rnaseh2a

Organism:

Mus musculus

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Gene Name:

Ribonuclease H2 subunit A

Gene ID:

MGI:1916974

Protein ID:

Q9CWY8

Persistent Id:

PTN000102693

Alternate Ids:

755527232(GI)	XM_011248498(refSeq)
BC038158(EMBL)	Ribonuclease HI large subunit(Synonym)
MGI:1916974(MGI)	ENSMUST00000109738(Ensembl_TRS)
ENSMUSG00000052926(Ensembl)	RNH2A_MOUSE(UniProtKB-ID)
ENSMUSP00000105360(Ensembl_PRO)	Q8CHY8(AltAccession)
69724(GeneID)	AAH38158(EMBL-CDS)
3.1.26.4(EC)	Rnaseh2a(Symbol)
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PANTHER Classification

PANTHER Family:	RIBONUCLEASE H2 SUBUNIT A (PTHR10954)
PANTHER Subfamily:	RIBONUCLEASE H2 SUBUNIT A (PTHR10954:SF7)
PANTHER GO-slim Molecular Function:	RNA endonuclease activity
PANTHER GO-slim Biological Process:	mismatch repair RNA catabolic process DNA replication
PANTHER GO-slim Cellular Component:	catalytic complex intracellular protein-containing complex
PANTHER protein class:	endoribonuclease

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	RNA-DNA hybrid ribonuclease activity, RNA binding, metal ion binding
GO BP Complete:	mismatch repair, DNA replication, removal of RNA primer, RNA catabolic process
GO CC Complete:	cytosol, ribonuclease H2 complex, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=18518\|UniProtKB=O75792	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000010542.4\|UniProtKB=H2QFH0	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000005846.3\|UniProtKB=G3QSS9	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000045010.2\|UniProtKB=F6U5A6	Macaca mulatta	LDO
RAT\|RGD=1307248\|UniProtKB=Q5U209	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000009661\|UniProtKB=Q2TBT5	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00005032933.1\|UniProtKB=F1SDX8	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000007013.3\|UniProtKB=A0A9L0RYB3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000000474.5\|UniProtKB=M3VUU3	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845015846.1\|UniProtKB=A0A8I3P1A1	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000006997.4\|UniProtKB=F6XVJ9	Monodelphis domestica	LDO
ANOCA\|Ensembl=ENSACAG00000003338.4\|UniProtKB=H9G7E1	Anolis carolinensis	LDO
XENLA\|Gene=rnaseh2a.L\|UniProtKB=Q4FZN2	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-945840\|UniProtKB=Q6P7L6	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000004042.2\|UniProtKB=H2LGF8	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-976\|UniProtKB=Q6IQM9	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000007890.1\|UniProtKB=W5MMH3	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000006190.3\|UniProtKB=F7B1W3	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118414461\|UniProtKB=A0A9J7L1F4	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC763203\|UniProtKB=A0A7M7G456	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00004383\|UniProtKB=Q9U6P6	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00027367\|UniProtKB=A8WYE0	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00304301\|UniProtKB=A0A8R1Z2J5	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0031252\|UniProtKB=Q9VPP5	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP007741\|UniProtKB=A0A1S4GW38	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC011359\|UniProtKB=D6X470	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_230884\|UniProtKB=E9GHZ3	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW001993\|UniProtKB=B7PAV9	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG73260\|UniProtKB=T1G1C2	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g210941\|UniProtKB=A7SEB2	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG51212\|UniProtKB=B3SDM2	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_25972\|UniProtKB=A9V104	Monosiga brevicollis	LDO
YEAST\|SGD=S000005016\|UniProtKB=P53942	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AER363W\|UniProtKB=Q756A4	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000175451\|UniProtKB=Q5AGX6	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_D23661g\|UniProtKB=Q6C813	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_05114\|UniProtKB=Q5B2W6	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_1G07600\|UniProtKB=Q4WJ14	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU09608\|UniProtKB=Q9P5X8	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_01636\|UniProtKB=A7E8K8	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_01231\|UniProtKB=Q0V433	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC4G9.02\|UniProtKB=Q10236	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_02039\|UniProtKB=B6JZJ9	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNI02520\|UniProtKB=Q5KBH4	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_06131\|UniProtKB=A0A0D1DQ00	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_16050\|UniProtKB=E3L1N8	Puccinia graminis	LDO
PUCGT\|EnsemblGenome=PGTG_10935\|UniProtKB=E3KMX0	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_8789\|UniProtKB=F4NV99	Batrachochytrium dendrobatidis	LDO
ENTH1\|Gene_ORFName=EHI_134360\|UniProtKB=B1N370	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_084700\|UniProtKB=C4M1K1	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0292584\|UniProtKB=Q54D13	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_26608\|UniProtKB=F0Z8W3	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_36_0640\|UniProtKB=Q8ISS8	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb10.70.2140\|UniProtKB=Q38B94	Trypanosoma brucei	LDO
GIAIC\|EnsemblGenome=GL50803_6483\|UniProtKB=A8B5I7	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_262310\|UniProtKB=A2DUE3	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_0623900\|UniProtKB=C6KT75	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00029875001\|UniProtKB=A0BL27	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00029234001\|UniProtKB=A0BI31	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_17008\|UniProtKB=B8C1R2	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GW85_PHYRM\|UniProtKB=H3GW85	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_17g701350v5\|UniProtKB=A0A2K3CNY2	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00040p00093940\|UniProtKB=W1PSK0	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_89G00230\|UniProtKB=A0A0K9NKD4	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma02_g02890\|UniProtKB=A0A804HYN3	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_010697mg\|UniProtKB=K3Y905	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3008G040300\|UniProtKB=C5YS45	Sorghum bicolor	O
SETIT\|EnsemblGenome=SETIT_012525mg\|UniProtKB=K3YE64	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3010G241600\|UniProtKB=C5Z8P5	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb406890\|UniProtKB=K7UBU5	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os11g0153900\|UniProtKB=Q53QG3	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_4g42210v3\|UniProtKB=I1IU91	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0460390\|UniProtKB=A0A8I6YQF0	Hordeum vulgare subsp. vulgare	LDO
NELNU\|Gene=LOC104589003\|UniProtKB=A0A1U7YY08	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110790891\|UniProtKB=A0A9R0IL43	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr14g0660611\|UniProtKB=A0A251TBD0	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C200088800\|UniProtKB=A0A9R1WFI8	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a010913mg\|UniProtKB=A0A022RE79	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_29720\|UniProtKB=A0A2G2Y6A8	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400023970\|UniProtKB=M1C7Q6	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc11g006860.2\|UniProtKB=A0A3Q7IPB9	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107791603\|UniProtKB=A0A1S3ZXU9	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107771872\|UniProtKB=A0A1S3Y3T9	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi13g00975\|UniProtKB=F6HPY3	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_G02689\|UniProtKB=A0A059BHP0	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_C04P55060.1\|UniProtKB=A0A078J1G4	Brassica napus	O
BRANA\|EnsemblGenome=GSBRNA2T00080473001\|UniProtKB=A0A078JTV6	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra032040\|UniProtKB=M4ETB0	Brassica campestris	LDO
ARATH\|TAIR=locus=2040189\|UniProtKB=Q9SEZ6	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107904365\|UniProtKB=A0A1U8J799	Gossypium hirsutum	O
GOSHI\|Gene=LOC107904187\|UniProtKB=A0A1U8J6K6	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_044005\|UniProtKB=A0A061FQ66	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g022427mg\|UniProtKB=A0A067DS68	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_010G239600v3\|UniProtKB=A0A2K1YZD8	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_008G019800v3\|UniProtKB=B9HKP4	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_10G062100\|UniProtKB=A0A2C9V3M9	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1539780\|UniProtKB=B9RPT7	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_20G111500\|UniProtKB=I1NFE4	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_10G278500\|UniProtKB=I1LF08	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g111980\|UniProtKB=A0A072W210	Medicago truncatula	LDO
JUGRE\|Gene=LOC109002154\|UniProtKB=A0A6P9EFB5	Juglans regia	O
JUGRE\|EnsemblGenome=Jr14_04870\|UniProtKB=A0A2I4E2R8	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_4G015800\|UniProtKB=A0A0A0KTZ4	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_2G069600\|UniProtKB=M5X1Z0	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_233940\|UniProtKB=D8SFY2	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_439531\|UniProtKB=D8R5Q9	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c13_7860\|UniProtKB=A0A2K1JL69	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0006s0052\|UniProtKB=A0A2R6XPH6	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_003340010\|UniProtKB=A0A1Y1IEK7	Klebsormidium nitens	LDO
NITMS\|EnsemblGenome=Nmar_1393\|UniProtKB=A9A3M7	Nitrosopumilus maritimus	O
KORCO\|EnsemblGenome=Kcr_1147\|UniProtKB=B1L614	Korarchaeum cryptofilum	O
KORCO\|EnsemblGenome=Kcr_0703\|UniProtKB=B1L4S5	Korarchaeum cryptofilum	O
KORCO\|EnsemblGenome=Kcr_0350\|UniProtKB=B1L3S7	Korarchaeum cryptofilum	O
SACS2\|EnsemblGenome=SSO2384\|UniProtKB=Q97W56	Sulfolobus solfataricus	O
PYRAE\|EnsemblGenome=PAE1216\|UniProtKB=Q8ZXL6	Pyrobaculum aerophilum	O
METAC\|EnsemblGenome=MA_1959\|UniProtKB=Q8TPF4	Methanosarcina acetivorans	O
METJA\|EnsemblGenome=MJ_0135\|UniProtKB=Q57599	Methanocaldococcus jannaschii	O
HALSA\|EnsemblGenome=VNG_1984G\|UniProtKB=Q9HNR3	Halobacterium salinarum	O
THEKO\|EnsemblGenome=TK0805\|UniProtKB=O74035	Thermococcus kodakaraensis	O
MYCGE\|Gene_OrderedLocusName=MG199\|UniProtKB=P47441	mycoplasma genitalium	O
STRR6\|EnsemblGenome=spr0365\|UniProtKB=P59660	Streptococcus pneumoniae	O
STAA8\|EnsemblGenome=SAOUHSC_01095\|UniProtKB=Q2FZD7	Staphylococcus aureus	O
LISMO\|EnsemblGenome=CAC99306\|UniProtKB=Q8Y7P5	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_28620\|UniProtKB=P94541	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_4556\|UniProtKB=Q817J0	Bacillus cereus	O
CHLTR\|EnsemblGenome=CT_008\|UniProtKB=O84011	Chlamydia trachomatis	O
CHLAA\|EnsemblGenome=Caur_1039\|UniProtKB=A9WIH1	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO5812\|UniProtKB=O69989	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=Rv2902c\|UniProtKB=P9WH01	Mycobacterium tuberculosis	O
CLOBH\|Gene_OrderedLocusName=CBO2441\|UniProtKB=A5I4L9	Clostridium botulinum	O
STRR6\|EnsemblGenome=spr1044\|UniProtKB=Q8DPR3	Streptococcus pneumoniae	O
STAA8\|EnsemblGenome=SAOUHSC_01215\|UniProtKB=Q2FZ38	Staphylococcus aureus	O
LISMO\|EnsemblGenome=CAC99351\|UniProtKB=Q8Y7K4	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_16060\|UniProtKB=O31744	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_3835\|UniProtKB=Q819W9	Bacillus cereus	O
THEMA\|EnsemblGenome=TM_0915\|UniProtKB=Q9X017	Thermotoga maritima	O
DEIRA\|EnsemblGenome=DR_1949\|UniProtKB=Q9RT20	Deinococcus radiodurans	O
GLOVI\|Gene=rnhA\|UniProtKB=Q7NKH1	Gloeobacter violaceus	O
SYNY3\|EnsemblGenome=BAA16659\|UniProtKB=P72657	Synechocystis	O
LEPIN\|EnsemblGenome=LA_2386\|UniProtKB=Q8F3L5	Leptospira interrogans	O
BACTN\|EnsemblGenome=BT_3412\|UniProtKB=Q8A293	Bacteroides thetaiotaomicron	O
CHLTR\|EnsemblGenome=CT_029\|UniProtKB=O84032	Chlamydia trachomatis	O
AQUAE\|EnsemblGenome=aq_1768\|UniProtKB=O67644	Aquifex aeolicus	O
AQUAE\|EnsemblGenome=aq_1955\|UniProtKB=O67768	Aquifex aeolicus	O
THEYD\|EnsemblGenome=THEYE_A0822\|UniProtKB=B5YK98	Thermodesulfovibrio yellowstonii	O
DICTD\|EnsemblGenome=Dtur_0708\|UniProtKB=B8DZR0	Dictyoglomus turgidum	O
DICTD\|EnsemblGenome=Dtur_1531\|UniProtKB=B8E2G1	Dictyoglomus turgidum	O
FUSNN\|EnsemblGenome=FN1371\|UniProtKB=Q8RDX3	Fusobacterium nucleatum	O
HELPY\|EnsemblGenome=HP_1323\|UniProtKB=P56121	Helicobacter pylori	O
NEIMB\|EnsemblGenome=NMB0192\|UniProtKB=Q9K1G1	Neisseria meningitidis serogroup b	O
GEOSL\|EnsemblGenome=GSU0649\|UniProtKB=Q74FG0	Geobacter sulfurreducens	O
BRADU\|EnsemblGenome=BAC47786\|UniProtKB=Q89S84	Bradyrhizobium diazoefficiens	O
COXBU\|EnsemblGenome=CBU_1339\|UniProtKB=Q83BZ8	Coxiella burnetii	O
HAEIN\|EnsemblGenome=HI_1059\|UniProtKB=P43808	Haemophilus influenzae	O
SHEON\|Gene_OrderedLocusName=SO_1643\|UniProtKB=Q8EGG1	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_2246\|UniProtKB=P52021	Vibrio cholerae	O
XANCP\|EnsemblGenome=XCC1359\|UniProtKB=Q8PAW7	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA3642\|UniProtKB=Q9HXY9	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM0230\|UniProtKB=P0A2C1	Salmonella typhimurium	O
YERPE\|EnsemblGenome=YP_2792\|UniProtKB=Q8ZH54	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAA77858\|UniProtKB=P10442	Escherichia coli	O