PANTHER Gene Information

Gene Symbol(s):

Smdt1

Organism:

Mus musculus

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Gene Name:

Essential MCU regulator, mitochondrial

Gene ID:

MGI:1916279

Protein ID:

Q9DB10

Persistent Id:

PTN002141665

Alternate Ids:

69029(GeneID)	ENSMUSP00000023086(Ensembl_PRO)
Smdt1{ECO:0000312\|MGI:MGI:1916279}(Symbol)	EMRE(Synonym)
BC028457(EMBL)	ENSMUST00000023086(Ensembl_TRS)
ENSMUSG00000022452(Ensembl)	AAH92006(EMBL-CDS)
NP_081190(refSeq)	20306591(GI)
EMRE_MOUSE(UniProtKB-ID)	Q58EA5(AltAccession)
MGI:1916279(MGI)
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PANTHER Classification

PANTHER Family:	ESSENTIAL MCU REGULATOR, MITOCHONDRIAL (PTHR33904)
PANTHER Subfamily:	ESSENTIAL MCU REGULATOR, MITOCHONDRIAL (PTHR33904:SF1)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	mitochondrial calcium ion homeostasis calcium ion transmembrane transport mitochondrial transmembrane transport
PANTHER GO-slim Cellular Component:	calcium channel complex inner mitochondrial membrane protein complex
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	channel activator activity, protein-macromolecule adaptor activity, molecular_function
GO BP Complete:	calcium import into the mitochondrion, mitochondrial calcium ion homeostasis, cellular response to calcium ion starvation, mitochondrial calcium ion transmembrane transport
GO CC Complete:	uniplex complex, mitochondrion, mitochondrial inner membrane, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Transport of small molecules, Processing of SMDT1, Mitochondrial calcium ion transport, Mitochondrial protein degradation, Metabolism of proteins

Orthologs

ID	Organism	Type
HUMAN\|HGNC=25055\|UniProtKB=Q9H4I9	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000014448.4\|UniProtKB=K7AKX1	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000007903.3\|UniProtKB=G3QY06	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000013061.4\|UniProtKB=F7H5N7	Macaca mulatta	LDO
RAT\|RGD=1311310\|UniProtKB=A0A8I6ASM9	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000051189.1\|UniProtKB=A0A3Q1M209	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000009508\|UniProtKB=Q2M2S2	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000020945.4\|UniProtKB=F1SJP7	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000049904.1\|UniProtKB=A0A9L0SUH0	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000000892.5\|UniProtKB=M3VVL5	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845015069.1\|UniProtKB=A0A8I3NVN5	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000025054.2\|UniProtKB=F6PLZ3	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000007037.1\|UniProtKB=F6UFP3	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000002673.2\|UniProtKB=F7ADM1	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010009809.1\|UniProtKB=F1NJF9	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000003926.2\|UniProtKB=G1KCC5	Anolis carolinensis	LDO
XENLA\|Gene=smdt1.L\|UniProtKB=A0A1L8GNG8	Xenopus laevis	LDO
XENLA\|Gene=smdt1\|UniProtKB=Q5XG64	Xenopus laevis	LDO
ORYLA\|Ensembl=ENSORLG00000028765.1\|UniProtKB=A0A3B3IED3	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000014736.2\|UniProtKB=H2MII7	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000004088.2\|UniProtKB=H2LGM2	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-141212-9\|UniProtKB=A0A0J9YJ98	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000011934.1\|UniProtKB=W5N217	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118429260\|UniProtKB=A0A9J7N717	Branchiostoma floridae	LDO
CAEEL\|WormBase=WBGene00008980\|UniProtKB=Q9U3I4	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00029628\|UniProtKB=A8X4D2	Caenorhabditis briggsae	LDO
DROME\|FlyBase=FBgn0263026\|UniProtKB=M9NEV9	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0062440\|UniProtKB=Q7JX57	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP011291\|UniProtKB=Q7QHP6	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC012057\|UniProtKB=D6X268	Tribolium castaneum	LDO
IXOSC\|EnsemblGenome=ISCW012881\|UniProtKB=B7QFA1	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG96981\|UniProtKB=T1G9E8	helobdella robusta	LDO