PANTHER Gene Information   
Gene Symbol(s): Kat8
Organism: Mus musculus
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Gene Name: Histone acetyltransferase KAT8
Gene ID: MGI:1915023
Protein ID: Q9D1P2
Persistent Id: PTN000065160
Alternate Ids:
MGI:1915023(MGI) MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1(Synonym)
Q8BJ76(AltAccession) KAT8_MOUSE(UniProtKB-ID)
23271123(GI) 2.3.1.48 {ECO:0000269|PubMed:31794431}(EC)
BAC26411(EMBL-CDS) ENSMUSG00000030801(Ensembl)
AK018002(EMBL) 67773(GeneID)
Kat8(Symbol)
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PANTHER Classification
PANTHER Family: HISTONE ACETYLTRANSFERASE (PTHR10615)
PANTHER Subfamily: HISTONE ACETYLTRANSFERASE KAT8 (PTHR10615:SF82)  
PANTHER GO-slim Molecular Function: histone acetyltransferase activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component: NuA4 histone acetyltransferase complex
PANTHER protein class: histone modifying enzyme
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: acetyltransferase activity, histone H2BK5 acetyltransferase activity, histone H3K4 acetyltransferase activity, histone H4K16 acetyltransferase activity, histone H2BK12 acetyltransferase activity, histone H3K36 acetyltransferase activity, histone H3K27 acetyltransferase activity, protein-lysine-acetyltransferase activity, promoter-specific chromatin binding, histone H3K14 acetyltransferase activity, histone H2AK5 acetyltransferase activity, zinc ion binding, histone H3K9 acetyltransferase activity, histone H3K23 acetyltransferase activity, histone H3K18 acetyltransferase activity, histone H4K8 acetyltransferase activity, histone H4K5 acetyltransferase activity, protein propionyltransferase activity, histone H3K122 acetyltransferase activity, histone H4K12 acetyltransferase activity, protein binding, transcription coactivator activity, RNA polymerase II-specific DNA-binding transcription factor binding, histone H2AK9 acetyltransferase activity, histone H3K56 acetyltransferase activity, histone H4 acetyltransferase activity, enzyme binding
GO BP Complete: negative regulation of type I interferon production, post-embryonic hemopoiesis, transcription initiation-coupled chromatin remodeling, positive regulation of transcription initiation by RNA polymerase II, dosage compensation by inactivation of X chromosome, neurogenesis, positive regulation of skeletal muscle satellite cell differentiation, regulation of mitochondrial transcription, negative regulation of epithelial to mesenchymal transition, regulation of mRNA processing, negative regulation of DNA-templated transcription, positive regulation of DNA-templated transcription, oogenesis, regulation of autophagy, myeloid cell differentiation
GO CC Complete: nucleus, NuA4 histone acetyltransferase complex, MSL complex, mitochondrion, nuclear matrix, kinetochore, chromosome, NSL complex, histone acetyltransferase complex, nucleoplasm, MLL1 complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Chromatin organization, Formation of WDR5-containing histone-modifying complexes, HATs acetylate histones, Chromatin modifying enzymes, Gene expression (Transcription), Epigenetic regulation of gene expression

Orthologs