PANTHER Gene Information

Gene Symbol(s):

Lonp2

Organism:

Mus musculus

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Gene Name:

Lon protease homolog 2, peroxisomal

Gene ID:

MGI:1914137

Protein ID:

Q9DBN5

Persistent Id:

PTN000005577

Alternate Ids:

BAE30373(EMBL-CDS)	74143958(GI)
MGI:1914137(MGI)	ENSMUSG00000047866(Ensembl)
Q3TGR0(AltAccession)	LONP2_MOUSE(UniProtKB-ID)
3.4.21.53 {ECO:0000255\|HAMAP-Rule:MF_03121}(EC)	NM_001168591(refSeq)
Lonp2(Symbol)	AK004843(EMBL)
66887(GeneID)	LONP2(Synonym)
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PANTHER Classification

PANTHER Family:	ATP DEPENDENT LON PROTEASE FAMILY MEMBER (PTHR10046)
PANTHER Subfamily:	LON PROTEASE HOMOLOG 2, PEROXISOMAL (PTHR10046:SF24)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	serine protease

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	ATP hydrolysis activity, ATP binding, protein binding, serine-type endopeptidase activity, protease binding, ATP-dependent peptidase activity, peptidase activity, enzyme binding
GO BP Complete:	protein import into peroxisome matrix, regulation of fatty acid beta-oxidation, protein quality control for misfolded or incompletely synthesized proteins, protein targeting to peroxisome, protein processing
GO CC Complete:	nucleus, peroxisome, cytoplasm, peroxisomal matrix

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Peroxisomal protein import, Protein localization

Orthologs

ID	Organism	Type
HUMAN\|HGNC=20598\|UniProtKB=Q86WA8	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000008093.3\|UniProtKB=H2QB22	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000006559.3\|UniProtKB=G3QUL8	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000007397.4\|UniProtKB=H9ELZ6	Macaca mulatta	LDO
RAT\|RGD=1305466\|UniProtKB=Q3MIB4	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000010867\|UniProtKB=Q3SX23	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000023391.4\|UniProtKB=F1REY1	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000022436.4\|UniProtKB=A0A3Q2HES2	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000005281.6\|UniProtKB=A0A5F5XL09	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845004588.1\|UniProtKB=A0A8I3MTD9	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000012957.4\|UniProtKB=F7DC85	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000014848.4\|UniProtKB=F7BY25	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010024230.1\|UniProtKB=A0A8V0ZRI7	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000014302.3\|UniProtKB=H9GL04	Anolis carolinensis	LDO
XENLA\|Gene=lonp2\|UniProtKB=Q2TAF8	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-948726\|UniProtKB=F7A0I5	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000013529.2\|UniProtKB=H2MEF8	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-041212-1\|UniProtKB=Q5PQY6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000007553.1\|UniProtKB=W5MLA6	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118409527\|UniProtKB=A0A9J7HVQ4	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC585210\|UniProtKB=A0A7M7N6R7	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00013541\|UniProtKB=Q9XW87	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG23035\|UniProtKB=A8Y3E2	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00091885\|UniProtKB=A0A2A6BP92	Pristionchus pacificus	LDO
IXOSC\|EnsemblGenome=ISCW008144\|UniProtKB=B7PSX0	Ixodes scapularis	LDO
TRIAD\|EnsemblGenome=TriadG50226\|UniProtKB=B3RVV2	Trichoplax adhaerens	LDO
EREGS\|EnsemblGenome=AGOS_AFL121W\|UniProtKB=Q755E4	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000175783\|UniProtKB=Q59YV0	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_F23595g\|UniProtKB=Q6C0L7	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_00122\|UniProtKB=Q5BH58	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_5G11750\|UniProtKB=Q4WVD9	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU08303\|UniProtKB=Q7SA85	Neurospora crassa	LDO
PHANO\|EnsemblGenome=SNOG_13933\|UniProtKB=Q0U2R2	Phaeosphaeria nodorum	LDO
USTMA\|EnsemblGenome=UMAG_05558\|UniProtKB=A0A0D1DQA9	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_07428\|UniProtKB=E3K9Z7	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_12969\|UniProtKB=F4P833	Batrachochytrium dendrobatidis	LDO
PLAF7\|EnsemblGenome=PF3D7_1414900\|UniProtKB=Q8ILU7	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00036859001\|UniProtKB=A0CBA9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00015847001\|UniProtKB=A0DD71	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00034120001\|UniProtKB=A0C1H7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00027868001\|UniProtKB=A0BE69	Paramecium tetraurelia	LDO
PHYRM\|Gene=H3GFZ4_PHYRM\|UniProtKB=H3GFZ4	Phytophthora ramorum	LDO
AMBTC\|EnsemblGenome=AMTR_s00048p00009570\|UniProtKB=U5D258	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_106G00130\|UniProtKB=A0A0K9Q4C3	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma02_g05340\|UniProtKB=A0A804HZI3	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma01_g02990\|UniProtKB=A0A804HPP5	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_000256mg\|UniProtKB=K3XED9	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3002G276100\|UniProtKB=C5X686	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb103510\|UniProtKB=A0A804MQ83	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb319680\|UniProtKB=P93647	Zea mays	LDO
ORYSJ\|Gene_OrderedLocusName=LOC_Os09g36300\|UniProtKB=Q0J032	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_4g36160v3\|UniProtKB=I1IS64	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0499120\|UniProtKB=A0A8I6Y500	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS5D02G328300\|UniProtKB=A0A3B6MWZ6	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5A02G321500\|UniProtKB=A0A3B6KJS4	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5B02G322000\|UniProtKB=A0A3B6LPQ3	Triticum aestivum	LDO
NELNU\|Gene=LOC104609856\|UniProtKB=A0A1U8B560	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110781714\|UniProtKB=A0A9R0I4P4	Spinacia oleracea	LDO
SPIOL\|Gene=LONP2_SPIOL\|UniProtKB=O04979	Spinacia oleracea	LDO
SPIOL\|Gene=LONP2_SPIOL\|UniProtKB=O04979	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HanXRQr2_Chr08g0359821\|UniProtKB=A0A9K3NE02	Helianthus annuus	O
HELAN\|Gene_ORFName=HannXRQ_Chr15g0475561\|UniProtKB=A0A251S838	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C600324090\|UniProtKB=A0A9R1VAJ0	Lactuca sativa	O
HELAN\|EnsemblGenome=HanXRQr2_Chr03g0131321\|UniProtKB=A0A251VCT1	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C600332070\|UniProtKB=A0A9R1V5W9	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a001102mg\|UniProtKB=A0A022R2J5	Erythranthe guttata	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a0010891mg\|UniProtKB=A0A022PNH0	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_00780\|UniProtKB=A0A1U8GIA3	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400001842\|UniProtKB=M0ZNR5	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc08g077440.3\|UniProtKB=A0A3Q7HU70	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107799448\|UniProtKB=A0A1S4AN57	Nicotiana tabacum	O
TOBAC\|Gene=LOC107787424\|UniProtKB=A0A1S3ZJA1	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi02g00617\|UniProtKB=D7TTJ0	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_E00326\|UniProtKB=A0A059C1R0	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_A06P45340.1\|UniProtKB=A0A078H4G6	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra024968\|UniProtKB=M4E862	Brassica campestris	LDO
ARATH\|TAIR=locus=2171037\|UniProtKB=O64948	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107924027\|UniProtKB=A0A1U8L8R0	Gossypium hirsutum	O
GOSHI\|Gene=LOC107886394\|UniProtKB=A0A1U8HPC7	Gossypium hirsutum	O
GOSHI\|Gene=LOC107912194\|UniProtKB=A0A1U8JZQ2	Gossypium hirsutum	O
GOSHI\|Gene=LOC107920092\|UniProtKB=A0A1U8KVQ1	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_015805\|UniProtKB=A0A061G2P0	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g003349mg\|UniProtKB=A0A067EC00	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_001G148400v3\|UniProtKB=B9MTW6	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_003G086000v3\|UniProtKB=A0A2K2B3R5	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_17G020300\|UniProtKB=A0A2C9U458	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0520240\|UniProtKB=B9SS30	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_17G151100\|UniProtKB=I1MVB0	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_05G068600\|UniProtKB=I1K0Z2	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_4g099020\|UniProtKB=A0A072UQE3	Medicago truncatula	LDO
SOYBN\|EnsemblGenome=GLYMA_01G203100\|UniProtKB=I1J9N9	Glycine max	O
MEDTR\|EnsemblGenome=MTR_5g013790\|UniProtKB=G7JYP5	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr02_12160\|UniProtKB=A0A6P9E1X8	Juglans regia	O
JUGRE\|EnsemblGenome=Jr01_24720\|UniProtKB=A0A6P9EHT5	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_3G016960\|UniProtKB=A0A0A0L5B9	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_5G050100\|UniProtKB=M5WS05	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_444435\|UniProtKB=D8SAJ0	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_141788\|UniProtKB=D8QWE3	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_150045\|UniProtKB=D8RU73	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c14_7840\|UniProtKB=A0A2K1JGT1	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c10_9020\|UniProtKB=A0A2K1JYA8	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c9_13420\|UniProtKB=A0A2K1K325	Physcomitrella patens	LDO
KLENI\|Gene_ORFName=KFL_000640310\|UniProtKB=A0A1Y1HQE9	Klebsormidium nitens	LDO
KORCO\|EnsemblGenome=Kcr_0252\|UniProtKB=B1L3I3	Korarchaeum cryptofilum	LDO
PYRAE\|EnsemblGenome=PAE3507\|UniProtKB=Q8ZSZ4	Pyrobaculum aerophilum	LDO
METAC\|EnsemblGenome=MA_3289\|UniProtKB=Q8TKV5	Methanosarcina acetivorans	O
METJA\|EnsemblGenome=MJ_1417\|UniProtKB=Q58812	Methanocaldococcus jannaschii	O
HALSA\|EnsemblGenome=VNG_0303G\|UniProtKB=Q9HSC3	Halobacterium salinarum	O
THEKO\|EnsemblGenome=TK1264\|UniProtKB=Q8NKS6	Thermococcus kodakaraensis	O
METAC\|EnsemblGenome=MA_1862\|UniProtKB=Q8TPP4	Methanosarcina acetivorans	LDO
METJA\|EnsemblGenome=MJ_1318\|UniProtKB=Q58714	Methanocaldococcus jannaschii	LDO
THEKO\|EnsemblGenome=TK2168\|UniProtKB=Q5JHI9	Thermococcus kodakaraensis	LDO
MYCGE\|EnsemblGenome=MG_239\|UniProtKB=P47481	mycoplasma genitalium	O
CLOBH\|Gene_OrderedLocusName=CBO3228\|UniProtKB=A5I6V8	Clostridium botulinum	O
BACSU\|EnsemblGenome=BSU_28200\|UniProtKB=P37945	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_4477\|UniProtKB=Q817Q4	Bacillus cereus	O
DEIRA\|EnsemblGenome=DR_1974\|UniProtKB=Q9RSZ5	Deinococcus radiodurans	O
FUSNN\|EnsemblGenome=FN2014\|UniProtKB=Q8RHK0	Fusobacterium nucleatum	O
NEIMB\|EnsemblGenome=NMB1231\|UniProtKB=Q9JZ95	Neisseria meningitidis serogroup b	O
GEOSL\|EnsemblGenome=GSU1790\|UniProtKB=Q74C84	Geobacter sulfurreducens	O
BRADU\|Gene=lon\|UniProtKB=Q89KG3	Bradyrhizobium diazoefficiens	O
COXBU\|EnsemblGenome=CBU_0740\|UniProtKB=Q83DJ0	Coxiella burnetii	O
HAEIN\|EnsemblGenome=HI_0462\|UniProtKB=P43864	Haemophilus influenzae	O
SHEON\|Gene_OrderedLocusName=SO_1796\|UniProtKB=Q8EG17	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_1920\|UniProtKB=Q9KQS8	Vibrio cholerae	O
XANCP\|EnsemblGenome=XCC0977\|UniProtKB=Q8PBY4	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA1803\|UniProtKB=Q9I2T9	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM0450\|UniProtKB=Q8ZRB9	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO3155\|UniProtKB=A0A5P8YJ65	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAE76219\|UniProtKB=P0A9M0	Escherichia coli	O
CLOBH\|Gene_OrderedLocusName=CBO1439\|UniProtKB=A5I1R9	Clostridium botulinum	O
THEMA\|EnsemblGenome=TM_1869\|UniProtKB=Q9X2I2	Thermotoga maritima	O
LEPIN\|EnsemblGenome=LB_201\|UniProtKB=Q8EXK7	Leptospira interrogans	O
THEYD\|EnsemblGenome=THEYE_A1753\|UniProtKB=B5YH54	Thermodesulfovibrio yellowstonii	O
GEOSL\|EnsemblGenome=GSU2433\|UniProtKB=Q74AE3	Geobacter sulfurreducens	O
HAEIN\|EnsemblGenome=HI_1324\|UniProtKB=P43865	Haemophilus influenzae	O
SHEON\|Gene_OrderedLocusName=SO_1857\|UniProtKB=Q8EFV8	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_1482\|UniProtKB=Q9KS01	Vibrio cholerae	O
SALTY\|EnsemblGenome=STM1068\|UniProtKB=Q8ZQ69	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO1431\|UniProtKB=A0A5P8YGH0	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAA35713\|UniProtKB=P75867	Escherichia coli	O
SHEON\|Gene_OrderedLocusName=SO_3391\|UniProtKB=Q8EBV4	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_A0975\|UniProtKB=Q9KKX5	Vibrio cholerae	O
PSEAE\|EnsemblGenome=PA4576\|UniProtKB=Q9HVK8	Pseudomonas aeruginosa	O
THEYD\|EnsemblGenome=THEYE_A0758\|UniProtKB=B5YK35	Thermodesulfovibrio yellowstonii	LDO
GEOSL\|EnsemblGenome=GSU0923\|UniProtKB=Q74EN9	Geobacter sulfurreducens	LDO
STRCO\|Gene_OrderedLocusName=SCO5202\|UniProtKB=Q9FCI6	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=Rv3194c\|UniProtKB=O53340	Mycobacterium tuberculosis	O
STRR6\|EnsemblGenome=spr1782\|UniProtKB=Q8DNE7	Streptococcus pneumoniae	O
LISMO\|Gene=Q8Y5K8_LISMO\|UniProtKB=Q8Y5K8	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_15050\|UniProtKB=O34470	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_3926\|UniProtKB=Q819P3	Bacillus cereus	O
CHLAA\|EnsemblGenome=Caur_0798\|UniProtKB=A9WGB5	Chloroflexus aurantiacus	O
CHLAA\|EnsemblGenome=Caur_0086\|UniProtKB=A9WBD3	Chloroflexus aurantiacus	O
CHLAA\|EnsemblGenome=Caur_0303\|UniProtKB=A9WCY5	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO5285\|UniProtKB=Q9EVK2	Streptomyces coelicolor	O
CLOBH\|Gene_OrderedLocusName=CBO3621\|UniProtKB=A5I7Z4	Clostridium botulinum	O
CLOBH\|Gene_OrderedLocusName=CBO3229\|UniProtKB=A5I6V9	Clostridium botulinum	O
BACSU\|EnsemblGenome=BSU_28210\|UniProtKB=P42425	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_4478\|UniProtKB=Q817Q3	Bacillus cereus	O
THEMA\|EnsemblGenome=TM_1633\|UniProtKB=Q9X1W8	Thermotoga maritima	O
DEIRA\|EnsemblGenome=DR_0349\|UniProtKB=Q9RXG4	Deinococcus radiodurans	O
BACTN\|EnsemblGenome=BT_0837\|UniProtKB=Q8A9H8	Bacteroides thetaiotaomicron	O
AQUAE\|EnsemblGenome=aq_242\|UniProtKB=O66605	Aquifex aeolicus	O
THEYD\|EnsemblGenome=THEYE_A0859\|UniProtKB=B5YKD3	Thermodesulfovibrio yellowstonii	O
DICTD\|EnsemblGenome=Dtur_1560\|UniProtKB=B8E2J0	Dictyoglomus turgidum	O
GEOSL\|EnsemblGenome=GSU2105\|UniProtKB=Q74BD6	Geobacter sulfurreducens	O
SALTY\|EnsemblGenome=STM4491\|UniProtKB=Q8ZK16	Salmonella typhimurium	O
GEOSL\|EnsemblGenome=GSU3193\|UniProtKB=Q747S2	Geobacter sulfurreducens	O