PANTHER Gene Information

Gene Symbol(s):

Ube2w

Organism:

Mus musculus

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Gene Name:

Ubiquitin-conjugating enzyme E2 W

Gene ID:

MGI:1914049

Protein ID:

Q8VDW4

Persistent Id:

PTN000630475

Alternate Ids:

26346891(GI)	2.3.2.23(EC)
Q8BVJ8(AltAccession)	NP_080049(refSeq)
MGI:1914049(MGI)	UBE2W_MOUSE(UniProtKB-ID)
BAC34377(EMBL-CDS)	ENSMUSG00000025939(Ensembl)
ENSMUST00000117146(Ensembl_TRS)	AK050679(EMBL)
Ubiquitin carrier protein W(Synonym)	Ube2w(Symbol)
66799(GeneID)	ENSMUSP00000112741(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	UBIQUITIN-CONJUGATING ENZYME E2 (PTHR24068)
PANTHER Subfamily:	UBIQUITIN-CONJUGATING ENZYME E2 W (PTHR24068:SF153)
PANTHER GO-slim Molecular Function:	ubiquitin conjugating enzyme activity
PANTHER GO-slim Biological Process:	proteasome-mediated ubiquitin-dependent protein catabolic process protein polyubiquitination
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:	ubiquitin-protein ligase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ubiquitin-protein transferase activity, ATP binding, protein binding, ubiquitin protein ligase binding, ubiquitin conjugating enzyme activity
GO BP Complete:	DNA repair, proteasome-mediated ubiquitin-dependent protein catabolic process, protein K11-linked ubiquitination, protein quality control for misfolded or incompletely synthesized proteins, negative regulation of TORC1 signaling, protein polyubiquitination, protein monoubiquitination, antiviral innate immune response, cellular response to misfolded protein
GO CC Complete:	nucleus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Immune System, Antigen processing: Ubiquitination & Proteasome degradation, Class I MHC mediated antigen processing & presentation, Protein ubiquitination, Adaptive Immune System, Metabolism of proteins, Post-translational protein modification, Synthesis of active ubiquitin: roles of E1 and E2 enzymes

Orthologs

ID	Organism	Type
HUMAN\|HGNC=25616\|UniProtKB=Q96B02	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000020348.6\|UniProtKB=H2R378	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000007459.3\|UniProtKB=A0A2I2Z7B4	Gorilla gorilla gorilla	LDO
RAT\|RGD=6503620\|UniProtKB=B5DEI4	Rattus norvegicus	LDO
RAT\|RGD=15005970\|UniProtKB=M0R6B6	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000048843\|UniProtKB=A6H795	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000006177.5\|UniProtKB=A0A287BC59	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000027854.4\|UniProtKB=M3WYV9	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845028719.1\|UniProtKB=A0A8I3QHD3	Canis lupus familiaris	LDO
ORNAN\|Ensembl=ENSOANG00000008597.4\|UniProtKB=A0A6I8NRU2	Ornithorhynchus anatinus	LDO
ORYLA\|Ensembl=ENSORLG00000025733.1\|UniProtKB=A0A3B3HVW3	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-050506-94\|UniProtKB=Q4VBH4	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-050113-1\|UniProtKB=Q1JPX4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000003697.1\|UniProtKB=W5M7P1	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000002766.3\|UniProtKB=F7AH68	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_115629\|UniProtKB=C3ZNC4	Branchiostoma floridae	LDO
CAEEL\|WormBase=WBGene00006711\|UniProtKB=Q9XWF6	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG19703\|UniProtKB=A8XWI7	Caenorhabditis briggsae	LDO
DROME\|FlyBase=FBgn0033544\|UniProtKB=A1Z8B5	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP005324\|UniProtKB=Q7PIU2	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC002937\|UniProtKB=D6WH24	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_211776\|UniProtKB=E9GIF0	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW019323\|UniProtKB=B7PTB2	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG185420\|UniProtKB=T1FMS9	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g174994\|UniProtKB=A7SW95	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG50463\|UniProtKB=B3S1U8	Trichoplax adhaerens	LDO
CANAL\|CGD=CAL0000192881\|UniProtKB=Q5A5R2	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_F31955g\|UniProtKB=Q6BZP7	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_02413\|UniProtKB=C8VNX4	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_2G13690\|UniProtKB=Q4X0F1	Neosartorya fumigata	LDO
SCLS1\|Gene_ORFName=SS1G_10020\|UniProtKB=A7EXF9	Sclerotinia sclerotiorum	LDO
CRYNJ\|EnsemblGenome=CNE04250\|UniProtKB=Q5KGB0	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_03443\|UniProtKB=A0A0D1C3P4	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_00822\|UniProtKB=E3JTS4	Puccinia graminis	LDO
DICDI\|dictyBase=DDB_G0268938\|UniProtKB=Q55EY8	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_157952\|UniProtKB=F1A0F8	Dictyostelium purpureum	LDO
TRIV3\|Gene_ORFName=TVAG_130740\|UniProtKB=A2FTA9	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_476010\|UniProtKB=A2DA24	Trichomonas vaginalis	O
PLAF7\|EnsemblGenome=PF3D7_1243700\|UniProtKB=Q8I4Z3	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_1345500\|UniProtKB=Q8IDP1	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_1412900.1\|UniProtKB=Q8ILW5	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00034321001\|UniProtKB=A0C227	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00032900001\|UniProtKB=A0BWY1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00030369001\|UniProtKB=A0BMG6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00016175001\|UniProtKB=A0DE66	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_36045\|UniProtKB=B8C7B4	Thalassiosira pseudonana	LDO
CHLRE\|EnsemblGenome=CHLRE_02g141450v5\|UniProtKB=A0A2K3E455	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00002p00234950\|UniProtKB=W1NUB1	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_218G00070\|UniProtKB=A0A0K9PJQ8	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_392G00010\|UniProtKB=A0A0K9P4E5	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_4G00430\|UniProtKB=A0A0K9NYI4	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma09_g25940\|UniProtKB=A0A804KNS2	Musa acuminata subsp. malaccensis	LDO
MUSAM\|EnsemblGenome=Ma06_g31510\|UniProtKB=A0A804JMI6	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma09_g10400\|UniProtKB=A0A804KI34	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma04_g27600\|UniProtKB=A0A804IUL1	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_023498mg\|UniProtKB=K3ZAC7	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3008G189300\|UniProtKB=C5YT12	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb134110\|UniProtKB=B4FMX0	Zea mays	O
ORYSJ\|EnsemblGenome=Os12g0636800\|UniProtKB=Q2QLM1	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_4g00660v3\|UniProtKB=A0A0Q3HBZ6	Brachypodium distachyon	O
WHEAT\|EnsemblGenome=TraesCS5A02G006200\|UniProtKB=W5G1C0	Triticum aestivum	O
SETIT\|EnsemblGenome=SETIT_040733mg\|UniProtKB=K4AP85	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3001G136900\|UniProtKB=C5WPM7	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb217340\|UniProtKB=A0A804P934	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os03g0681400\|UniProtKB=Q9AYE3	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_1g12480v3\|UniProtKB=I1GPK6	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.4HG0334410\|UniProtKB=F2DS45	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS4A02G288800\|UniProtKB=A0A3B6HXE4	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS4B02G026000\|UniProtKB=A0A3B6IN27	Triticum aestivum	LDO
NELNU\|Gene=LOC104595596\|UniProtKB=A0A1U8A0V0	Nelumbo nucifera	LDO
POPTR\|EnsemblGenome=POPTR_002G030800v3\|UniProtKB=A9PC20	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_005G232100v3\|UniProtKB=A9PH82	Populus trichocarpa	LDO
NELNU\|Gene=LOC104610559\|UniProtKB=A0A1U8B3W1	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110798889\|UniProtKB=A0A9R0K6R4	Spinacia oleracea	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a015306mg\|UniProtKB=A0A022QZ73	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_13305\|UniProtKB=A0A1U8GBI5	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400003753\|UniProtKB=M0ZWM9	Solanum tuberosum	O
TOBAC\|Gene=LOC107776491\|UniProtKB=A0A1S3YHZ6	Nicotiana tabacum	O
TOBAC\|Gene=LOC107769767\|UniProtKB=A0A1S3XX43	Nicotiana tabacum	O
CAPAN\|EnsemblGenome=T459_06395\|UniProtKB=A0A1U8FW96	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400003613\|UniProtKB=M0ZVZ8	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc02g084760.3\|UniProtKB=K4BAZ1	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107824880\|UniProtKB=A0A1S4D1H7	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107824081\|UniProtKB=A0A1S4CYR5	Nicotiana tabacum	O
TOBAC\|Gene=LOC107759180\|UniProtKB=A0A1S3WXX8	Nicotiana tabacum	LDO
VITVI\|Gene_OrderedLocusName=VIT_18s0001g13180\|UniProtKB=A5AEM8	Vitis vinifera	LDO
BRANA\|Gene_ORFName=GSBRNA2T00027606001\|UniProtKB=A0A078J250	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00043866001\|UniProtKB=A0A078JE31	Brassica napus	O
BRACM\|EnsemblGenome=Bra017759\|UniProtKB=M4DMM4	Brassica campestris	O
BRACM\|EnsemblGenome=Bra011680\|UniProtKB=A0A398AHL5	Brassica campestris	O
ARATH\|TAIR=locus=2115425\|UniProtKB=O23239	Arabidopsis thaliana	O
BRANA\|Gene_ORFName=DARMORV10_A07P41000.1\|UniProtKB=A0A078IBN6	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra015843\|UniProtKB=M4DH66	Brassica campestris	LDO
ARATH\|TAIR=locus=2018447\|UniProtKB=Q9FWT2	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107957952\|UniProtKB=A6MUS6	Gossypium hirsutum	O
GOSHI\|Gene=LOC107905467\|UniProtKB=A0A1U8JBD2	Gossypium hirsutum	LDO
GOSHI\|Gene=LOC107918005\|UniProtKB=A0A1U8KKB9	Gossypium hirsutum	O
GOSHI\|Gene=LOC107934253\|UniProtKB=A0A1U8M5M3	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_034118\|UniProtKB=A0A061FDS1	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g031319mg\|UniProtKB=A0A067H1C2	Citrus sinensis	LDO
RICCO\|Gene_ORFName=RCOM_1595790\|UniProtKB=B9R805	Ricinus communis	LDO
PRUPE\|EnsemblGenome=PRUPE_1G373500\|UniProtKB=M5XFV3	Prunus persica	LDO
PRUPE\|EnsemblGenome=PRUPE_7G162600\|UniProtKB=M5VX01	Prunus persica	LDO
SPIOL\|Gene=LOC110790575\|UniProtKB=A0A9R0IKQ5	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr09g0406941\|UniProtKB=A0A251TZN8	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C400202900\|UniProtKB=A0A9R1VT81	Lactuca sativa	O
HELAN\|Gene_ORFName=HanXRQr2_Chr14g0642941\|UniProtKB=A0A9K3H8E2	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr11g0471341\|UniProtKB=A0A251T8A8	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C200078200\|UniProtKB=A0A9R1W7V7	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a015314mg\|UniProtKB=A0A022R8Q4	Erythranthe guttata	O
TOBAC\|Gene=LOC107796639\|UniProtKB=A0A1S4AE14	Nicotiana tabacum	O
TOBAC\|Gene=LOC107799066\|UniProtKB=A0A1S4AMG6	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi04g02133\|UniProtKB=D7SP59	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_I02390\|UniProtKB=A0A059ARU5	Eucalyptus grandis	O
BRANA\|Gene_ORFName=DARMORV10_C06P01140.1\|UniProtKB=A0A078FHZ3	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00088571001\|UniProtKB=A0A078IDG6	Brassica napus	O
BRACM\|EnsemblGenome=Bra036332\|UniProtKB=M4F5H6	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00032965001\|UniProtKB=A0A078GM22	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00077380001\|UniProtKB=A0A078HZ19	Brassica napus	O
BRACM\|EnsemblGenome=Bra032210\|UniProtKB=M4ETS8	Brassica campestris	O
ARATH\|TAIR=locus=2028255\|UniProtKB=P42743	Arabidopsis thaliana	O
BRANA\|Gene_ORFName=GSBRNA2T00076903001\|UniProtKB=A0A078I3B7	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00053183001\|UniProtKB=A0A078H642	Brassica napus	O
BRACM\|EnsemblGenome=Bra027470\|UniProtKB=M4EFA8	Brassica campestris	O
ARATH\|TAIR=locus=2159981\|UniProtKB=Q9FMM0	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107935354\|UniProtKB=A0A1U8MCZ3	Gossypium hirsutum	O
GOSHI\|Gene=LOC107936522\|UniProtKB=A0A1U8MD24	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_000290\|UniProtKB=A0A061DLV4	Theobroma cacao	O
POPTR\|EnsemblGenome=POPTR_007G018700v3\|UniProtKB=B9HFA8	Populus trichocarpa	O
MEDTR\|EnsemblGenome=MTR_8g076490\|UniProtKB=G7LD21	Medicago truncatula	O
POPTR\|EnsemblGenome=POPTR_005G118600v3\|UniProtKB=B9MXK5	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_02G098800\|UniProtKB=A0A2C9WCG4	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_05G154600\|UniProtKB=A0A2C9VWJ2	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_01G140800\|UniProtKB=A0A2C9WM49	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0533330\|UniProtKB=B9S688	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_01G169700\|UniProtKB=C6SVP6	Glycine max	O
MEDTR\|EnsemblGenome=MTR_5g021260\|UniProtKB=G7KGB6	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr11_20730\|UniProtKB=A0A2I4EP61	Juglans regia	O
JUGRE\|EnsemblGenome=Jr11_07280\|UniProtKB=A0A6P9DTF3	Juglans regia	O
JUGRE\|EnsemblGenome=Jr11_07270\|UniProtKB=A0A2I4ERM3	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_4G045000\|UniProtKB=A0A0A0KUH0	Cucumis sativus	O
SELML\|EnsemblGenome=SELMODRAFT_159187\|UniProtKB=D8SXP0	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_270987\|UniProtKB=D8RNN4	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_172555\|UniProtKB=D8RL54	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c17_2700\|UniProtKB=A0A2K1J2J6	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c15_170\|UniProtKB=A0A7I4AXQ4	Physcomitrella patens	LDO