PANTHER Gene Information   
Gene Symbol(s): Icmt
Organism: Mus musculus
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Gene Name: Protein-S-isoprenylcysteine O-methyltransferase
Gene ID: MGI:1888594
Protein ID: Q9EQK7
Persistent Id: PTN000295619
Alternate Ids:
Prenylcysteine carboxyl methyltransferase(Synonym) 12082483(GI)
Icmt(Symbol) 57295(GeneID)
AAG48552(EMBL-CDS) AA022288(EMBL)
NP_598549(refSeq) 2.1.1.100 {ECO:0000250|UniProtKB:O60725}(EC)
MGI:1888594(MGI) ICMT_MOUSE(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: PROTEIN-S ISOPRENYLCYSTEINE O-METHYLTRANSFERASE (PTHR12714)
PANTHER Subfamily: PROTEIN-S-ISOPRENYLCYSTEINE O-METHYLTRANSFERASE (PTHR12714:SF9)  
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class: protein modifying enzyme
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: cAMP response element binding protein binding, protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
GO BP Complete: multicellular organism growth, bone mineralization, regulation of protein localization, CAAX-box protein maturation, determination of adult lifespan, C-terminal protein methylation, neuromuscular process, protein localization, regulation of Ras protein signal transduction, TOR signaling, S-adenosylmethioninamine metabolic process, protein methylation, fibroblast proliferation, in utero embryonic development, S-adenosylhomocysteine metabolic process, liver development, positive regulation of fibroblast proliferation, regulation of cellular senescence, methylation
GO CC Complete: endoplasmic reticulum membrane, endoplasmic reticulum
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Signal Transduction, MAPK1/MAPK3 signaling, Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation, Metabolism of proteins, MAPK family signaling cascades, RAF/MAP kinase cascade, RAS processing, Post-translational protein modification

Orthologs