PANTHER Gene Information   
Gene Symbol(s): Keap1
Organism: Mus musculus
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Gene Name: Kelch-like ECH-associated protein 1
Gene ID: MGI:1858732
Protein ID: Q9Z2X8
Persistent Id: PTN000697173
Alternate Ids:
AK152142(EMBL) INrf2 {ECO:0000303|Ref.2}(Synonym)
74219668(GI) ENSMUST00000194542(Ensembl_TRS)
CHEMBL3562164(ChEMBL) Keap1{ECO:0000303|PubMed:9887101,ECO:0000312|MGI:MGI:1858732}(Symbol)
NP_001103776(refSeq) ENSMUSP00000062467(Ensembl_PRO)
KEAP1_MOUSE(UniProtKB-ID) Q3U243(AltAccession)
50868(GeneID) MGI:1858732(MGI)
ENSMUSG00000003308(Ensembl) BAE35433(EMBL-CDS)
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PANTHER Classification
PANTHER Family: KELCH PROTEIN (PTHR24412)
PANTHER Subfamily: KELCH-LIKE ECH-ASSOCIATED PROTEIN 1 (PTHR24412:SF162)  
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class: scaffold/adaptor protein
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: identical protein binding, protein binding, RNA polymerase II-specific DNA-binding transcription factor binding, transcription regulator inhibitor activity, ubiquitin-like ligase-substrate adaptor activity, disordered domain specific binding
GO BP Complete: negative regulation of response to oxidative stress, regulation of DNA-templated transcription, regulation of epidermal cell differentiation, ubiquitin-dependent protein catabolic process, negative regulation of transcription by RNA polymerase II, negative regulation of gene expression, proteasome-mediated ubiquitin-dependent protein catabolic process, in utero embryonic development, cellular response to carbohydrate stimulus, regulation of autophagy, cellular response to interleukin-4, cellular response to oxidative stress, protein ubiquitination
GO CC Complete: adherens junction, focal adhesion, cytoplasm, centriolar satellite, cytosol, endoplasmic reticulum, protein-containing complex, midbody, Cul3-RING ubiquitin ligase complex, actin filament, inclusion body, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Cellular responses to stimuli, Immune System, Deubiquitination, Cellular response to chemical stress, KEAP1-NFE2L2 pathway, Antigen processing: Ubiquitination & Proteasome degradation, Neddylation, Class I MHC mediated antigen processing & presentation, Ub-specific processing proteases, Adaptive Immune System, Metabolism of proteins, Cellular responses to stress, Post-translational protein modification

Orthologs