PANTHER Gene Information

Gene Symbol(s):

Neu2

Organism:

Mus musculus

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Gene Name:

Sialidase-2

Gene ID:

MGI:1344417

Protein ID:

Q9JMH3

Persistent Id:

PTN000066670

Alternate Ids:

NP_001153637(refSeq)	Neu2(Symbol)
ENSMUST00000165109(Ensembl_TRS)	237512989(GI)
ENSMUSP00000065439(Ensembl_PRO)	23956(GeneID)
AB028023(EMBL)	CHEMBL4296071(ChEMBL)
3.2.1.18 {ECO:0000269\|PubMed:10329453, ECO:0000269\|PubMed:10713120}(EC)	MSS(Synonym)
NEUR2_MOUSE(UniProtKB-ID)	MGI:1344417(MGI)
ENSMUSG00000079434(Ensembl)	Q99NA3(AltAccession)
BAB39152(EMBL-CDS)
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PANTHER Classification

PANTHER Family:	SIALIDASE (PTHR10628)
PANTHER Subfamily:	SIALIDASE-2 (PTHR10628:SF6)
PANTHER GO-slim Molecular Function:	hydrolase activity, hydrolyzing O-glycosyl compounds
PANTHER GO-slim Biological Process:	carbohydrate catabolic process ceramide metabolic process glycolipid metabolic process carbohydrate derivative catabolic process sphingolipid catabolic process
PANTHER GO-slim Cellular Component:	intracellular membrane-bounded organelle cytoplasm membrane
PANTHER protein class:	hydrolase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	exo-alpha-sialidase activity
GO BP Complete:	glycoprotein catabolic process, positive regulation of myotube differentiation, oligosaccharide catabolic process, positive regulation of myoblast differentiation, ganglioside catabolic process
GO CC Complete:	catalytic complex, cytoplasm, membrane, cytosol, lysosome

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Synthesis of substrates in N-glycan biosythesis, Glycosphingolipid catabolism, Sphingolipid metabolism, Asparagine N-linked glycosylation, Glycosphingolipid metabolism, Metabolism, Metabolism of lipids, Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein, Metabolism of proteins, Sialic acid metabolism, Post-translational protein modification

Orthologs

ID	Organism	Type
HUMAN\|HGNC=7759\|UniProtKB=Q9Y3R4	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000013049.3\|UniProtKB=H2QJM5	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000005494.3\|UniProtKB=G3QRW5	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000001651.3\|UniProtKB=F7G6S2	Macaca mulatta	LDO
RAT\|RGD=3164\|UniProtKB=Q64627	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000020672.6\|UniProtKB=G5E5Q1	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000016297.3\|UniProtKB=F1SM45	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000030943.3\|UniProtKB=A0A9L0TJJ4	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000038619.3\|UniProtKB=A0A2I2V0G9	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845020896.1\|UniProtKB=A0A8I3PBB8	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000010460.3\|UniProtKB=F7F7Q7	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000007781.4\|UniProtKB=A0A6I8NMD8	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010022942.1\|UniProtKB=A0A8V0ZQN0	Gallus gallus	LDO
XENLA\|Gene=neu4.S\|UniProtKB=A0A8J0VAY4	Xenopus laevis	O
XENLA\|Gene=neu4.L\|UniProtKB=A0A1L8GBQ4	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-959717\|UniProtKB=K0PUT3	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000006455.2\|UniProtKB=H2LPW5	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-050522-125\|UniProtKB=Q503Z4	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000009785.1\|UniProtKB=W5MU88	lepisosteus oculatus	O
BRAFL\|Gene=LOC118406890\|UniProtKB=A0A9J7HP14	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC583431\|UniProtKB=A0A7M7P356	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100890472\|UniProtKB=A0A7M7P461	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115924908\|UniProtKB=A0A7M7NZ87	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC764416\|UniProtKB=A0A7M7NZA6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC755390\|UniProtKB=A0A7M7NZP4	Strongylocentrotus purpuratus	O
MONBE\|EnsemblGenome=MONBRDRAFT_28738\|UniProtKB=A9V918	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_34360\|UniProtKB=A9VB55	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_28502\|UniProtKB=A9V8C6	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_28715\|UniProtKB=A9V8Z4	Monosiga brevicollis	O
ASPFU\|EnsemblGenome=AFUA_4G13800\|UniProtKB=Q4WQS0	Neosartorya fumigata	O
TRYB2\|Gene_ORFName=Tb927.7.6830\|UniProtKB=Q57Y46	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb11.01.3240\|UniProtKB=Q383D7	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb927.8.7340\|UniProtKB=Q57YT6	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb927.7.6850\|UniProtKB=Q57XJ2	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb927.7.7480\|UniProtKB=Q57TY5	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb927.8.7350\|UniProtKB=Q57YT7	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb927.2.5280\|UniProtKB=Q585U3	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb927.5.640\|UniProtKB=Q57VF2	Trypanosoma brucei	O
TRIV3\|Gene_ORFName=TVAG_301370\|UniProtKB=A2E5F9	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_499550\|UniProtKB=A2EIP2	Trichomonas vaginalis	O
BACTN\|EnsemblGenome=BT_3608\|UniProtKB=Q8A1Q1	Bacteroides thetaiotaomicron	O
RHOBA\|EnsemblGenome=RB3006\|UniProtKB=Q7UUX1	Rhodopirellula baltica	O
STRR6\|EnsemblGenome=spr1531\|UniProtKB=Q8CWP8	Streptococcus pneumoniae	O
STRR6\|EnsemblGenome=spr1536\|UniProtKB=P62576	Streptococcus pneumoniae	O
BACTN\|EnsemblGenome=BT_0455\|UniProtKB=Q8AAK9	Bacteroides thetaiotaomicron	O
RHOBA\|EnsemblGenome=RB8895\|UniProtKB=Q7UMD4	Rhodopirellula baltica	O
VIBCH\|EnsemblGenome=VC_1784\|UniProtKB=P0C6E9	Vibrio cholerae	O
PSEAE\|EnsemblGenome=PA2794\|UniProtKB=G3XCV3	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM0928\|UniProtKB=P29768	Salmonella typhimurium	O