PANTHER Gene Information

Gene Symbol(s):

Prkab1

Organism:

Mus musculus

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Gene Name:

5'-AMP-activated protein kinase subunit beta-1

Gene ID:

MGI:1336167

Protein ID:

Q9R078

Persistent Id:

PTN000038877

Alternate Ids:

19079(GeneID)	ENSMUSP00000107630(Ensembl_PRO)
MGI:1336167(MGI)	AMPK subunit beta-1(Synonym)
AAF14222(EMBL-CDS)	AAKB1_MOUSE(UniProtKB-ID)
ENSMUSG00000029513(Ensembl)	BC016398(EMBL)
XM_006530201(refSeq)	23956234(GI)
Prkab1(Symbol)	Q91YN6(AltAccession)
CHEMBL4524004(ChEMBL)	ENSMUST00000111999(Ensembl_TRS)
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PANTHER Classification

PANTHER Family:	5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT (PTHR10343)
PANTHER Subfamily:	5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1 (PTHR10343:SF84)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	kinase modulator

Pathway Categories:

Gonadotropin-releasing hormone receptor pathway

AMPK

p53 pathway by glucose deprivation

AMP-activated protein kinase

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	protein kinase binding, AMP-activated protein kinase activity, protein binding, protein kinase activity
GO BP Complete:	cellular response to nutrient levels, signal transduction, positive regulation of gene expression, nail development, protein phosphorylation, fatty acid biosynthetic process, positive regulation of cold-induced thermogenesis
GO CC Complete:	nucleus, cytoplasm, cytosol, protein-containing complex, nucleotide-activated protein kinase complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Regulation of TP53 Activity through Phosphorylation, Macroautophagy, Regulation of TP53 Activity, Signal Transduction, Autophagy, Transcriptional Regulation by TP53, TP53 Regulates Metabolic Genes, Generic Transcription Pathway, Energy dependent regulation of mTOR by LKB1-AMPK, MTOR signalling, Gene expression (Transcription), RNA Polymerase II Transcription

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9378\|UniProtKB=Q9Y478	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000005520.4\|UniProtKB=G2HGR1	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000013047.3\|UniProtKB=G3RB90	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000019860.4\|UniProtKB=H9EPL6	Macaca mulatta	LDO
RAT\|RGD=71057\|UniProtKB=P80386	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000005940\|UniProtKB=Q5BIS9	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000009840.5\|UniProtKB=A0A8W4FFS0	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000011947.4\|UniProtKB=A0A3Q2LL18	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000000923.5\|UniProtKB=M3VVN1	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845028956.1\|UniProtKB=A0A8I3PY75	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000015269.4\|UniProtKB=F6TML6	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000009517.4\|UniProtKB=A0A6I8N1M4	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010023322.1\|UniProtKB=A0A8V1A092	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000003403.4\|UniProtKB=H9G7H2	Anolis carolinensis	LDO
XENLA\|Gene=prkab1.S\|UniProtKB=Q6GPZ3	Xenopus laevis	O
XENLA\|Gene=prkab1.L\|UniProtKB=A0A1L8I0A7	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-970882\|UniProtKB=F6T9F9	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000014704.2\|UniProtKB=H2MIF3	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030131-7172\|UniProtKB=Q6NY31	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000018371.2\|UniProtKB=H2MVZ1	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040718-377\|UniProtKB=Q6DHM2	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000001533.1\|UniProtKB=W5M045	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000004973.3\|UniProtKB=F6X915	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118404356\|UniProtKB=A0A9J7HGP3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118404355\|UniProtKB=A0A9J7KHT3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118404357\|UniProtKB=A0A9J7HGP4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118412602\|UniProtKB=A0A9J7KXN8	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC115919071\|UniProtKB=A0A7M7PTD9	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00012928\|UniProtKB=Q9NAH7	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00034008\|UniProtKB=A8XHB4	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00010115\|UniProtKB=Q9XUY2	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00029442\|UniProtKB=A8X4W7	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00089615\|UniProtKB=A0A2A6BFY1	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0260972\|UniProtKB=A1Z7Q8	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP008195\|UniProtKB=Q7Q442	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC007626\|UniProtKB=D2A2M0	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_203508\|UniProtKB=E9HJY8	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG63549\|UniProtKB=T1FXH3	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG86841\|UniProtKB=T1G6I0	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g192874\|UniProtKB=A7SRX9	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG16636\|UniProtKB=B3RKF7	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_25195\|UniProtKB=A9UYP2	Monosiga brevicollis	LDO
CANAL\|CGD=CAL0000181056\|UniProtKB=A0A1D8PFV7	Candida albicans	O
CRYNJ\|EnsemblGenome=CNC06020\|UniProtKB=Q5KJM3	Cryptococcus neoformans	O
PUCGT\|EnsemblGenome=PGTG_13375\|UniProtKB=E3KS81	Puccinia graminis	O
YEAST\|SGD=S000005117\|UniProtKB=P53885	Saccharomyces cerevisiae	O
YEAST\|SGD=S000001189\|UniProtKB=P38845	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ABL133C\|UniProtKB=Q75E06	Eremothecium gossypii	O
YARLI\|EnsemblGenome=YALI0_F04268g\|UniProtKB=Q6C2X7	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_F05852g\|UniProtKB=Q6C2R0	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_04988\|UniProtKB=Q5B392	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_3G09990\|UniProtKB=Q4WXM1	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU03870\|UniProtKB=V5IM39	Neurospora crassa	O
SCLS1\|Gene_ORFName=SS1G_10535\|UniProtKB=A7EYW9	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_01494\|UniProtKB=Q0V3C0	Phaeosphaeria nodorum	O
YEAST\|SGD=S000002830\|UniProtKB=P32578	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ADR194C\|UniProtKB=Q759S9	Eremothecium gossypii	O
YEAST\|SGD=S000003176\|UniProtKB=P34164	Saccharomyces cerevisiae	O
YEAST\|SGD=S000000829\|UniProtKB=Q04739	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AER361C\|UniProtKB=Q756A6	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000193576\|UniProtKB=A0A1D8PCL8	Candida albicans	O
CANAL\|CGD=CAL0000197988\|UniProtKB=Q5AKY0	Candida albicans	O
CANAL\|CGD=CAL0000178270\|UniProtKB=Q59X47	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_C00429g\|UniProtKB=Q6CDH7	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_E13926g\|UniProtKB=Q6C5Z1	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_06570\|UniProtKB=C8V0V3	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_6G04500\|UniProtKB=Q4WDE8	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU03837\|UniProtKB=Q7S744	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_00210\|UniProtKB=A7E4I8	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_09178\|UniProtKB=Q0UGD6	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPCC1919.03c\|UniProtKB=P78789	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_03802\|UniProtKB=B6K536	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNF04640\|UniProtKB=Q5KEQ5	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_00668\|UniProtKB=A0A0D1EAH3	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_03656\|UniProtKB=E3K075	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_22846\|UniProtKB=F4NVY8	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_4916\|UniProtKB=F4NXI0	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0281089\|UniProtKB=Q54UG7	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_153082\|UniProtKB=F0ZN05	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_23_0490\|UniProtKB=Q4QBC5	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb927.8.2450\|UniProtKB=Q57XE4	Trypanosoma brucei	LDO
GIAIC\|EnsemblGenome=GL50803_101919\|UniProtKB=A8BQL1	Giardia intestinalis	LDO
PARTE\|EnsemblGenome=GSPATT00037748001\|UniProtKB=A0CEU2	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_22399\|UniProtKB=B8C041	Thalassiosira pseudonana	LDO
CHLRE\|EnsemblGenome=CHLRE_06g283800v5\|UniProtKB=A0A2K3DPU1	Chlamydomonas reinhardtii	LDO
HELAN\|Gene_ORFName=HannXRQ_Chr03g0090621\|UniProtKB=A0A251VB08	Helianthus annuus	LDO
TOBAC\|Gene=LOC107821256\|UniProtKB=A0A1S4CQ35	Nicotiana tabacum	LDO